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Substance use disorders (SUDs) are a serious public health concern in the United States. Alcohol and cannabis are two of the most widely used substances. For adolescent/youth users of alcohol or cannabis, we propose a joint Bayesian…

Opioid Use Disorder (OUD) is a public health crisis costing the US billions of dollars annually in healthcare, lost workplace productivity, and crime. Analyzing longitudinal healthcare data is critical in addressing many real-world problems…

In the last decade, the United States has lost more than 500,000 people from an overdose involving prescription and illicit opioids making it a national public health emergency (USDHHS, 2017). Medical practitioners require robust and timely…

Computation and Language · Computer Science 2024-06-17 Chenghao Yang , Tuhin Chakrabarty , Karli R Hochstatter , Melissa N Slavin , Nabila El-Bassel , Smaranda Muresan

Introduction: Substance use disorders (SUDs) have emerged as a pressing public health concern in the United States, with adolescent substance use often leading to SUDs in adulthood. Effective strategies are needed to stem this progression.…

Applications · Statistics 2025-05-29 Tingfang Wang , Joseph M. Boden , Swati Biswas , Pankaj K. Choudhary

Despite the massive costs and widespread harms of substance use, most individuals with substance use disorders (SUDs) receive no treatment at all. Digital therapeutics platforms are an emerging low-cost and low-barrier means of extending…

Systems and Control · Electrical Eng. & Systems 2025-04-03 Eric Pulick , Yonatan Mintz

Overdose related to prescription opioids have reached an epidemic level in the US, creating an unprecedented national crisis. This has been exacerbated partly due to the lack of tools for physicians to help predict the risk of whether a…

Substance use disorders (SUDs) are a growing concern globally, necessitating enhanced understanding of the problem and its trends through data-driven research. Social media are unique and important sources of information about SUDs,…

Computation and Language · Computer Science 2024-05-13 Yao Ge , Sudeshna Das , Karen O'Connor , Mohammed Ali Al-Garadi , Graciela Gonzalez-Hernandez , Abeed Sarker

The United States is experiencing an opioid epidemic, and there were more than 10 million opioid misusers aged 12 or older each year. Identifying patients at high risk of Opioid Use Disorder (OUD) can help to make early clinical…

Opioid use disorder (OUD) is a leading health problem that affects individual well-being as well as general public health. Due to a variety of reasons, including the stigma faced by people using opioids, online communities for recovery and…

Social and Information Networks · Computer Science 2025-04-14 Tanmay Laud , Akadia Kacha-Ochana , Steven A. Sumner , Vikram Krishnasamy , Royal Law , Lyna Schieber , Munmun De Choudhury , Mai ElSherief

The United States (US) opioid crisis contributed to 81,806 fatalities in 2022. It has strained hospitals, treatment facilities, and law enforcement agencies due to the enormous resources and procedures needed to respond to the crisis. As a…

Computational Engineering, Finance, and Science · Computer Science 2025-07-14 Veronica M. White , Laura A. Albert

The United States is currently experiencing an unprecedented opioid crisis, and opioid overdose has become a leading cause of injury and death. Effective opioid addiction recovery calls for not only medical treatments, but also behavioral…

Social and Information Networks · Computer Science 2019-12-04 Zhou Yang , Spencer Bradshaw , Rattikorn Hewett , Fang Jin

Opioid overdose has emerged as a full blown epidemic in the United States. In the last few years, there has been an alarming increase in Opioid related deaths, resulting in the loss of 63,600 lives in 2016 alone. The epidemic which is…

Computers and Society · Computer Science 2018-05-16 Kaustav Basu , Sandipan Choudhuri , Arunabha Sen , Aniket Majumdar

The opioid epidemic is a crisis that has plagued the United States (US) for decades. One central issue is inequitable access to treatment for opioid use disorder (OUD), which puts certain populations at a higher risk of opioid overdose. We…

Physics and Society · Physics 2024-03-14 Joyce Luo , Bartolomeo Stellato

Predictive machine learning (ML) models are computational innovations that can enhance medical decision-making, including aiding in determining optimal timing for discharging patients. However, societal biases can be encoded into such…

Computers and Society · Computer Science 2024-12-10 Ugur Kursuncu , Aaron Baird , Yusen Xia

Stigma is a barrier to treatment for individuals struggling with substance use disorders (SUD), which leads to significantly lower treatment engagement rates. With only 7% of those affected receiving any form of help, societal stigma not…

Computation and Language · Computer Science 2025-01-28 Layla Bouzoubaa , Elham Aghakhani , Rezvaneh Rezapour

Online communities such as drug-related subreddits serve as safe spaces for people who use drugs (PWUD), fostering discussions on substance use experiences, harm reduction, and addiction recovery. Users' shared narratives on these forums…

Computation and Language · Computer Science 2024-06-19 Layla Bouzoubaa , Elham Aghakhani , Max Song , Minh Trinh , Rezvaneh Rezapour

In the last decade drug overdose deaths reached staggering proportions in the US. Besides the raw yearly deaths count that is worrisome per se, an alarming picture comes from the steep acceleration of such rate that increased by 21% from…

Computers and Society · Computer Science 2019-04-02 Duilio Balsamo , Paolo Bajardi , André Panisson

Online communities serve as essential support channels for People Who Use Drugs (PWUD), providing access to peer support and harm reduction information. The moderation of these communities involves consequential decisions affecting member…

Human-Computer Interaction · Computer Science 2026-01-06 Kaixuan Wang , Loraine Clarke , Carl-Cyril J Dreue , Guancheng Zhou , Jason T. Jacques

The opioid epidemic remains a major public health challenge in the United States, requiring a multi-pronged intervention approach to mitigate harms to communities. Given the heterogeneity of the epidemic across the country, it is crucial…

Applications · Statistics 2026-04-13 Abdulrahman A. Ahmed , M. Amin Rahimian , Qiushi Chen , Praveen Kumar

Opioid use disorder (OUD) is a chronic and relapsing condition that involves the continued and compulsive use of opioids despite harmful consequences. The development of medications with improved efficacy and safety profiles for OUD…

Biomolecules · Quantitative Biology 2023-03-02 Hongsong Feng , Jian Jiang , Guo-Wei Wei
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