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The de facto standard of dynamic histogram binning for radiomic feature extraction leads to an elevated sensitivity to fluctuations in annotated regions. This may impact the majority of radiomic studies published recently and contribute to…

Image and Video Processing · Electrical Eng. & Systems 2022-11-11 Darryl E. Wright , Cole Cook , Jason Klug , Panagiotis Korfiatis , Timothy L. Kline

Background. Radiomic features, derived from a region of interest (ROI) in medical images, are valuable as prognostic factors. Selecting an appropriate ROI is critical, and many recent studies have focused on leveraging multiple ROIs by…

Background: The reproducibility of machine-learning models in prostate cancer detection across different MRI vendors remains a significant challenge. Methods: This study investigates Support Vector Machines (SVM) and Random Forest (RF)…

Background: We aim to develop enriched radiomics features that integrate classical structural radiomics with novel functional radiomics derived from liver MRI for diagnosis and risk stratification in liver cancer. The proposed framework…

Federated learning and its application to medical image segmentation have recently become a popular research topic. This training paradigm suffers from statistical heterogeneity between participating institutions' local datasets, incurring…

Image and Video Processing · Electrical Eng. & Systems 2023-10-19 Matthis Manthe , Stefan Duffner , Carole Lartizien

Lung cancer remains the leading cause of cancer-related mortality worldwide, with survival strongly dependent on early detection. Standard-dose computed tomography (CT) screening using the Lung Imaging Reporting and Data System (Lung-RADS)…

Recent advancements in signal processing and machine learning coupled with developments of electronic medical record keeping in hospitals and the availability of extensive set of medical images through internal/external communication…

Computer Vision and Pattern Recognition · Computer Science 2019-07-24 Parnian Afshar , Arash Mohammadi , Konstantinos N. Plataniotis , Anastasia Oikonomou , Habib Benali

In this study, a radiomics approach was extended to optical fluorescence molecular imaging data for tissue classification, termed 'optomics'. Fluorescence molecular imaging is emerging for precise surgical guidance during head and neck…

Microscopy images contain rich information about how cells respond to perturbations, making them essential to applications like drug screening. To quantify images, researchers often use representation extraction methods, and recent years…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Emre Hayir , Lorin Crawford , Alex X. Lu

Radiomic models have been shown to outperform clinical data for outcome prediction in glioblastoma (GBM). However, clinical implementation is limited by lack of parameters standardization. We aimed to compare nine machine learning…

Predicting behavioral variables from neuroimaging modalities such as magnetic resonance imaging (MRI) has the potential to allow the development of neuroimaging biomarkers of mental and neurological disorders. A crucial processing step to…

Neurons and Cognition · Quantitative Biology 2025-07-29 Mikkel Schöttner Sieler , Thomas A. W. Bolton , Jagruti Patel , Patric Hagmann

Image features need to be robust against differences in positioning, acquisition and segmentation to ensure reproducibility. Radiomic models that only include robust features can be used to analyse new images, whereas models with non-robust…

Computer Vision and Pattern Recognition · Computer Science 2019-01-29 Alex Zwanenburg , Stefan Leger , Linda Agolli , Karoline Pilz , Esther G. C. Troost , Christian Richter , Steffen Löck

Neurodegenerative diseases are frequently associated with structural changes in the brain. Magnetic Resonance Imaging (MRI) scans can show these variations and therefore be used as a supportive feature for a number of neurodegenerative…

Feature selection is essential in the analysis of molecular systems and many other fields, but several uncertainties remain: What is the optimal number of features for a simplified, interpretable model that retains essential information?…

Machine Learning · Computer Science 2025-01-22 Romina Wild , Felix Wodaczek , Vittorio Del Tatto , Bingqing Cheng , Alessandro Laio

The development of face recognition algorithms by academic and commercial organizations is growing rapidly due to the onset of deep learning and the widespread availability of training data. Though tests of face recognition algorithm…

Computer Vision and Pattern Recognition · Computer Science 2022-03-11 John J. Howard , Eli J. Laird , Yevgeniy B. Sirotin , Rebecca E. Rubin , Jerry L. Tipton , Arun R. Vemury

Classifier specific (CS) and classifier agnostic (CA) feature importance methods are widely used (often interchangeably) by prior studies to derive feature importance ranks from a defect classifier. However, different feature importance…

Machine Learning · Computer Science 2022-02-08 Gopi Krishnan Rajbahadur , Shaowei Wang , Yasutaka Kamei , Ahmed E. Hassan

Radiomics features extract quantitative information from medical images, towards the derivation of biomarkers for clinical tasks, such as diagnosis, prognosis, or treatment response assessment. Different image discretization parameters…

The importance of radiomics features for predicting patient outcome is now well-established. Early study of prognostic features can lead to a more efficient treatment personalisation. For this reason new radiomics features obtained through…

Image and Video Processing · Electrical Eng. & Systems 2020-12-24 Paul Desbordes , Diksha , Benoit Macq

Radiomics is a relatively new field which utilises automatically identified features from radiological scans. It has found a widespread application, particularly in oncology because many of the important oncological biomarkers are not…

Quantitative Methods · Quantitative Biology 2024-09-26 Stanislav Kozák

Classical radiomic features have been designed to describe image appearance and intensity patterns. These features are directly interpretable and readily understood by radiologists. Compared with end-to-end deep learning (DL) models, lower…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Yaxi Chen , Simin Ni , Aleksandra Ivanova , Shaheer U. Saeed , Rikin Hargunani , Jie Huang , Chaozong Liu , Yipeng Hu