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Computational experiments have become essential for scientific discovery, allowing researchers to test hypotheses, analyze complex datasets, and validate findings. However, as computational experiments grow in scale and complexity, ensuring…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-03 Eleni Adamidi , Panayiotis Deligiannis , Nikos Foutris , Thanasis Vergoulis

Many scientific disciplines have traditionally advanced by iterating over hypotheses using labor-intensive trial-and-error, which is a slow and expensive process. Recent advances in computing, digitalization, and machine learning have…

Other Computer Science · Computer Science 2025-07-10 Carlos Sevilla-Salcedo , Armi Tiihonen , Mahsa Asadi , Kevin Sebastian Luck , Aras Umut Erarslan , Arto Klami , Samuel Kaski

Space-filling designs are crucial for efficient computer experiments, enabling accurate surrogate modeling and uncertainty quantification in many scientific and engineering applications, such as digital twin systems and cyber-physical…

Methodology · Statistics 2025-08-06 Xinwei Deng , Lulu Kang , C. Devon Lin

The ability to repeat the experiments from a research study and obtain similar results is a corner stone in experiment-based scientific discovery. This essential feature has been often ignored by the distributed computing and networking…

Networking and Internet Architecture · Computer Science 2014-10-08 Thierry Rakotoarivelo , Guillaume Jourjon , Olivier Mehani , Maximilian Ott , Mike Zink

Modern intelligent systems researchers form hypotheses about system behavior and then run experiments using one or more independent variables to test their hypotheses. We present SIERRA, a novel framework structured around that idea for…

Artificial Intelligence · Computer Science 2022-08-17 John Harwell , Maria Gini

We are developing the Virtual Experiences (Vx)Lab, a research and research training infrastructure and capability platform for global collaboration. VxLab comprises labs with visualisation capabilities, including underpinning networking to…

Other Computer Science · Computer Science 2015-11-02 Ian D. Peake , Jan Olaf Blech , Ian Thomas , Nicholas May , Heinz W. Schmidt , Lasith Fernando , Ravi Sreenivasamurthy

The complex and often safety-critical nature of cyber-physical energy systems makes validation a key challenge in facilitating the energy transition, especially when it comes to the testing on system level. Reliable and reproducible…

Living labs have been established across different countries to evaluate how the interaction between humans and buildings can be optimized to improve comfort, health, and energy savings. However, existing living labs can be too…

Human-Computer Interaction · Computer Science 2022-12-02 Alan Wang , Feng Yi Chang , Siavash Yousefi , Beatrice Li , Brad Campbell , Arsalan Heydarian

In recent years, the research community has raised serious questions about the reproducibility of scientific work. In particular, since many studies include some kind of computing work, reproducibility is also a technological challenge, not…

Software Engineering · Computer Science 2023-08-03 Lázaro Costa , Susana Barbosa , Jácome Cunha

Modern intelligent systems researchers employ the scientific method: they form hypotheses about system behavior, and then run experiments using one or more independent variables to test their hypotheses. We present SIERRA, a novel framework…

Robotics · Computer Science 2022-03-10 John Harwell , London Lowmanstone , Maria Gini

The Virtual Research Environment is an analysis platform developed at CERN serving the needs of scientific communities involved in European Projects. Its scope is to facilitate the development of end-to-end physics workflows, providing…

The enabling of scientific experiments that are embarrassingly parallel, long running and data-intensive into a cloud-based execution environment is a desirable, though complex undertaking for many researchers. The management of such…

Simulations with high accuracy are an essential part of scientific research to accelerate the innovation process. They are especially useful for finding novel approaches or optimizing existing methods. Today, powerful software tools are…

Medical Physics · Physics 2022-08-31 Patrick Vogel , Martin A. Rückert , Thomas Kampf , Volker C. Behr

At the frontier of most areas in science, computer simulations play a central role. The traditional division of natural science into experimental and theoretical investigations is now completely outdated. Instead, theory, simulation, and…

Astrophysics · Physics 2008-11-26 Piet Hut

The COVID-19 pandemic highlighted the challenges of maintaining hands-on laboratory instruction in undergraduate physics education. In response, we developed and deployed an interactive online physics laboratory platform designed to closely…

Physics Education · Physics 2026-03-02 Ashadul Halder , Shibaji Banerjee

Cloud computing provides a great opportunity for scientists, as it enables large-scale experiments that cannot are too long to run on local desktop machines. Cloud-based computations can be highly parallel, long running and data-intensive,…

Software Engineering · Computer Science 2016-12-07 Maria Spichkova , Heinz W. Schmidt , Ian E. Thomas , Iman I. Yusuf , Steve Androulakis , Grischa R. Meyer

Personalized medicine remains a major challenge for scientists. The rapid growth of Machine learning and Deep learning has made them a feasible al- ternative for predicting the most appropriate therapy for individual patients. However, the…

Machine Learning · Computer Science 2025-06-10 Antonio Jesús Banegas-Luna , Horacio Pérez-Sánchez

Social and behavioral scientists increasingly aim to study how humans interact, collaborate, and make decisions alongside artificial intelligence. However, the experimental infrastructure for such work remains underdeveloped: (1) few…

Human-Computer Interaction · Computer Science 2025-10-16 Crystal Qian , Vivian Tsai , Michael Behr , Nada Hussein , Léo Laugier , Nithum Thain , Lucas Dixon

We present a computer framework to store and evaluate likelihoods coming from High Energy Physics experiments. Due to its flexibility it can be interfaced with existing fitting codes and allows to uniform the interpretation of the…

Data Analysis, Statistics and Probability · Physics 2020-07-15 Jihyun Bhom , Marcin Chrzaszcz

To unleash the full potential of AI for Science, we must untether the agents from a purely digital environment. The agent's ability to control and explore in real-world labs is essential because the physical lab remains foundational to…

Systems and Control · Electrical Eng. & Systems 2026-05-19 Zhenning Yang , Yuhan Chen , Patrick Tser Jern Kon , Tongyuan Miao , Hongyi Lin , Venkat Viswanathan , Danai Koutra , Ang Chen
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