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Prostate cancer is the most dangerous cancer diagnosed in men worldwide. Prostate diagnosis has been affected by many factors, such as lesion complexity, observer visibility, and variability. Many techniques based on Magnetic Resonance…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Hussein Hashem , Yasmin Alsakar , Ahmed Elgarayhi , Mohammed Elmogy , Mohammed Sallah

Automating the radiotherapy treatment planning process is a technically challenging problem. The majority of automated approaches have focused on customizing and inferring dose volume objectives to used in plan optimization. In this work we…

Medical Physics · Physics 2017-01-04 Chris McIntosh , Thomas G. Purdie

An individualized dose rule recommends a dose level within a continuous safe dose range based on patient level information such as physical conditions, genetic factors and medication histories. Traditionally, personalized dose finding…

Methodology · Statistics 2020-07-21 Liangyu Zhu , Wenbin Lu , Michael R. Kosorok , Rui Song

Modern deep learning systems successfully solve many perception tasks such as object pose estimation when the input image is of high quality. However, in challenging imaging conditions such as on low-resolution images or when the image is…

Computer Vision and Pattern Recognition · Computer Science 2018-05-10 Sergey Prokudin , Peter Gehler , Sebastian Nowozin

Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging. One of the obstacles hindering such an integration are…

Hierarchical beam search in mmWave communications incurs substantial training overhead, necessitating deep learning-enabled beam predictions to effectively leverage channel priors and mitigate this overhead. In this study, we introduce a…

Information Theory · Computer Science 2024-01-04 Fan Meng , Cheng Zhang , Yongming Huang , Zhilei Zhang , Xiaoyu Bai , Zhaohua Lu

Deep learning (DL) models for segmenting various anatomical structures have achieved great success via a static DL model that is trained in a single source domain. Yet, the static DL model is likely to perform poorly in a continually…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Xiaofeng Liu , Helen A. Shih , Fangxu Xing , Emiliano Santarnecchi , Georges El Fakhri , Jonghye Woo

Background and purpose: Radiation-induced erectile dysfunction (RiED) is commonly seen in prostate cancer patients. Clinical trials have been developed in multiple institutions to investigate whether dose-sparing to the…

Image and Video Processing · Electrical Eng. & Systems 2023-02-06 Anjali Balagopal , Michael Dohopolski , Young Suk Kwon , Steven Montalvo , Howard Morgan , Ti Bai , Dan Nguyen , Xiao Liang , Xinran Zhong , Mu-Han Lin , Neil Desai , Steve Jiang

Multi-objective optimization (MOO) is a prevalent challenge for Deep Learning, however, there exists no scalable MOO solution for truly deep neural networks. Prior work either demand optimizing a new network for every point on the Pareto…

Machine Learning · Computer Science 2021-10-15 Michael Ruchte , Josif Grabocka

In radiotherapy for head and neck cancer, the radiation dose delivered to the pharyngeal mucosa (mucosal lining of the throat) is thought to be a major contributing factor to dysphagia (swallowing dysfunction), the most commonly reported…

We determine how prediction methods combine with optimization methods in two-stage knowledge-based planning (KBP) pipelines to produce radiation therapy treatment plans. We trained two dose prediction methods, a generative adversarial…

Medical Physics · Physics 2019-11-01 Aaron Babier , Rafid Mahmood , Andrea L. McNiven , Adam Diamant , Timothy C. Y. Chan

Traditional X-ray computed tomography (CT) scanning strategies typically select projection angles uniformly and allocate dose equally. In practice, however, CT scans often need to be fast, radiation-efficient, and adaptive. Sparse-view…

Medical Physics · Physics 2026-04-24 Tianyuan Wang , Daniël M. Pelt , Felix Lucka , Tristan van Leeuwen , K. Joost Batenburg

The field of Radiation Oncology is uniquely positioned to benefit from the use of artificial intelligence to fully automate the creation of radiation treatment plans for cancer therapy. This time-consuming and specialized task combines…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Kuancheng Wang , Hai Siong Tan , Rafe Mcbeth

The cluster dose concept offers an alternative to the radiobiological effectiveness (RBE)-based model for describing radiation-induced biological effects. This study examines the application of a neural network to predict cluster dose…

Medical Physics · Physics 2025-10-29 Miriam Schwarze , Hui Khee Looe , Björn Poppe , Leo Thomas , Hans Rabus

${\bf Purpose}$: Earlier work showed that IVIM-NET$_{orig}$, an unsupervised physics-informed deep neural network, was more accurate than other state-of-the-art intravoxel-incoherent motion (IVIM) fitting approaches to DWI. This study…

Background: Dose calculation and optimization algorithms in proton therapy treatment planning often have high computational requirements regarding time and memory. This can hinder the implementation of efficient workflows in clinics and…

Medical Physics · Physics 2023-04-18 D. Pross , S. Wuyckens , S. Deffet , E. Sterpin , J. A. Lee , K. Souris

Inverse treatment planning in radiation therapy is formulated as optimization problems. The objective function and constraints consist of multiple terms designed for different clinical and practical considerations. Weighting factors of…

Recently deep learning has been playing a major role in the field of computer vision. One of its applications is the reduction of human judgment in the diagnosis of diseases. Especially, brain tumor diagnosis requires high accuracy, where…

Computer Vision and Pattern Recognition · Computer Science 2018-09-24 Zahra Sobhaninia , Safiyeh Rezaei , Alireza Noroozi , Mehdi Ahmadi , Hamidreza Zarrabi , Nader Karimi , Ali Emami , Shadrokh Samavi

In this paper, we develop a deep learning (DL)-guided hybrid beam and power allocation approach for multiuser millimeter-wave (mmWave) networks, which facilitates swift beamforming at the base station (BS). The following persisting…

Signal Processing · Electrical Eng. & Systems 2023-05-24 Yuwen Cao , Tomoaki Ohtsuki , Setareh Maghsudi , Tony Q. S. Quek

The two-dimensional nature of mammography makes estimation of the overall breast density challenging, and estimation of the true patient-specific radiation dose impossible. Digital breast tomosynthesis (DBT), a pseudo-3D technique, is now…