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Quantification of neuronal correlations in neuron populations helps us to understand neural coding rules. Such quantification could also reveal how neurons encode information in normal and disease conditions like Alzheimer's and…

Neurons and Cognition · Quantitative Biology 2021-05-10 Sathish Ande , Srinivas Avasarala , Ajith Karunarathne , Lopamudra Giri , Soumya Jana

Neurons in the brain behave as a network of coupled nonlinear oscillators processing information by rhythmic activity and interaction. Several technological approaches have been proposed that might enable mimicking the complex information…

Applied Physics · Physics 2018-11-07 M. Vogel , B. Zimmermann , J. Wild , F. Schwarzhuber , C. Mewes , T. Mewes , J. Zweck , C. H. Back

The experimental study of neural networks requires simultaneous measurements of a massive number of neurons, while monitoring properties of the connectivity, synaptic strengths and delays. Current technological barriers make such a mission…

Neurons and Cognition · Quantitative Biology 2016-01-12 Amir Goldental , Pinhas Sabo , Shira Sardi , Roni Vardi , Ido Kanter

Biological systems use neural circuits to integrate input information and produce outputs. Synaptic convergence, where multiple neurons converge their inputs onto a single downstream neuron, is common in natural neural circuits. However,…

Mesoscale and Nanoscale Physics · Physics 2026-02-04 Wendy Otieno , Alex Gabbitas , Debi Pattnaik , Pavel Borisov , Sergey Savel'ev , Alexander G. Balanov

Human brain contains about 10 billion neurons, each of which has about 10~10,000 nerve endings from which neurotransmitters are released in response to incoming spikes, and the released neurotransmitters then bind to receptors located in…

Neurons and Cognition · Quantitative Biology 2012-03-06 Xuejuan Zhang , Jianfeng Feng

To thrive in dynamic environments, animals must be capable of rapidly and flexibly adapting behavioral responses to a changing context and internal state. Examples of behavioral flexibility include faster stimulus responses when attentive…

Neurons and Cognition · Quantitative Biology 2021-01-27 David Wyrick , Luca Mazzucato

The highly irregular spiking activity of cortical neurons and behavioral variability suggest that the brain could operate in a fundamentally probabilistic way. Mimicking how the brain implements and learns probabilistic computation could be…

Neural and Evolutionary Computing · Computer Science 2024-04-23 Yang Qi , Zhichao Zhu , Yiming Wei , Lu Cao , Zhigang Wang , Jie Zhang , Wenlian Lu , Jianfeng Feng

Interaction via pulses is common in many natural systems, especially neuronal. In this article we study one of the simplest possible systems with pulse interaction: a phase oscillator with delayed pulsatile feedback. When the oscillator…

Chaotic Dynamics · Physics 2015-12-14 Vladimir Klinshov , Leonhard Luecken , Dmitry Shchapin , Vladimir Nekorkin , Serhiy Yanchuk

Neural encoding is a field in neuroscience that focuses on characterizing how information from stimuli is encoded in the spiking activity of neurons. When more than one stimulus is present, a theory known as multiplexing posits that neurons…

Methodology · Statistics 2025-03-12 Nicholas Marco , Jennifer M. Groh , Surya T. Tokdar

This paper attempts to make feasible the evolutionary emergence of novelty in a supposedly deterministic world which behavior is associated with those of the mathematical dynamical systems. The work was motivated by the observation of…

Adaptation and Self-Organizing Systems · Physics 2024-06-26 R. Herrero , F. Pi , J. Rius , G. Orriols

Mounting evidence shows that oscillatory activity is widespread in cell signaling. Here we review some of this recent evidence, focusing on both the molecular mechanisms that potentially underlie such dynamical behavior, and the potential…

Cell Behavior · Quantitative Biology 2022-04-15 Pablo Casani-Galdon , Jordi Garcia-Ojalvo

Spontaneous cortical population activity exhibits a multitude of oscillatory patterns, which often display synchrony during slow-wave sleep or under certain anesthetics and stay asynchronous during quiet wakefulness. The mechanisms behind…

Neurons and Cognition · Quantitative Biology 2018-06-20 Rodrigo F. O. Pena , Michael A. Zaks , Antonio C. Roque

Presented with sensory challenges, living cells employ extensive noisy, fluctuating signalling and communication among themselves to compute a physiologically proper response which often results in symmetry breaking. We propose, based on…

Biological Physics · Physics 2022-06-17 Dean Korošak , Andraž Stožer , Marjan Slak Rupnik

The co-occurrence of action potentials of pairs of neurons within short time intervals is known since long. Such synchronous events can appear time-locked to the behavior of an animal and also theoretical considerations argue for a…

Neurons and Cognition · Quantitative Biology 2022-05-17 Moritz Helias , Tom Tetzlaff , Markus Diesmann

The neural mechanism of memory has a very close relation with the problem of representation in artificial intelligence. In this paper a computational model was proposed to simulate the network of neurons in brain and how they process…

Neurons and Cognition · Quantitative Biology 2020-12-02 Hui Wei

Complex coherent dynamics is present in a wide variety of neural systems. A typical example is the voltage transitions between up and down states observed in cortical areas in the brain. In this work, we study this phenomenon via a…

Neurons and Cognition · Quantitative Biology 2015-05-19 Jorge F. Mejias , Hilbert J. Kappen , Joaquin J. Torres

Many natural systems including the brain comprise coupled non-uniformly stimulated elements. In this paper we show that heterogeneously driven networks of excitatory-inhibitory units exhibit striking collective phenomena, including…

Adaptation and Self-Organizing Systems · Physics 2016-03-23 Varsha Sreenivasan , Shakti N. Menon , Sitabhra Sinha

In a series of two papers, we investigate the mechanisms by which complex oscillations are generated in a class of nonlinear dynamical systems with resets modeling the voltage and adaptation of neurons. This first paper presents…

Dynamical Systems · Mathematics 2016-11-10 Jonathan E. Rubin , Justyna Signerska-Rynkowska , Jonathan D. Touboul , Alexandre Vidal

In this paper, we investigated the neural spikes synchronisation in a neural network with synaptic plasticity and external perturbation. In the simulations the neural dynamics is described by the Hodgkin Huxley model considering chemical…

At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such…

Neurons and Cognition · Quantitative Biology 2020-11-12 Lia Papadopoulos , Christopher W. Lynn , Demian Battaglia , Danielle S. Bassett