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Andrew J. deMello is professor of Biochemical Engineering in the Department of Chemistry and Applied Biosciences at ETH Z\"urich. In this contribution he describes the efforts that his lab has undertaken in developing novel microfluidic…
Monodisperse lipid-coated microbubbles are a promising route to unlock the full potential of ultrasound contrast agents for medical diagnosis and therapy. Here, we present a stand-alone lab-on-a-chip instrument that allows microbubbles to…
Small volume fluid handling in single and multiphase microfluidics provides a promising strategy for efficient bio-chemical assays, low-cost point-of-care diagnostics and new approaches to scientific discoveries. However multiple barriers…
A low cost fluorescence-based optical system is developed for detecting the presence of certain microorganisms and molecules within a diluted sample. A specifically designed device setup compatible with conventional 96 well plates is chosen…
Effective mixing is essential for biochemical reactions. In droplet-based microfluidics, immediate mixing of substances upon contact in the droplet formation stage can greatly enhance the uniformity of chemical reactions. Furthermore, it…
Conventional electrical circuits are generally rigid in their components and working styles which are not flexible and stretchable. From an alternative, liquid metal based soft electronics is offering important opportunities for innovating…
Microfluidics-based biochips are soon expected to revolutionize clinical diagnosis, DNA sequencing, and other laboratory procedures involving molecular biology. Most microfluidic biochips are based on the principle of continuous fluid flow…
Many species, from single-cell bacteria to advanced animals, use molecular communication (MC) to share information with each other via chemical signals. Although MC is mostly studied in microscale, new practical applications emerge in…
We present DropleX, the first system that enables liquid sensing using the capacitive touchscreen of commodity tablets. DropleX detects microliter-scale liquid samples, and performs non-invasive, through-container measurements for liquid…
Droplets, sub-millilitre liquid volumes with at least one interface, have traditionally served as compartments for storing, transporting, and delivering materials. Beyond familiar applications in food, coatings, and consumer goods, they…
In multi-agent collaborative sensing systems, substantial communication overhead from information exchange significantly limits scalability and real-time performance, especially in bandwidth-constrained environments. This often results in…
While numerous methods achieving remarkable performance exist in the Object Detection literature, addressing data distribution shifts remains challenging. Continual Learning (CL) offers solutions to this issue, enabling models to adapt to…
The optical response of a suspension microdroplet is governed not only by the properties of the dispersed phase, but also by the finite size and optical structure of the droplet itself. As a result, the interpretation of scattered-light…
Biocomputing systems based on engineered bacteria can lead to novel tools for environmental monitoring and detection of metabolic diseases. In this paper, we propose a Bacterial Molecular Computing on a Chip (BMCoC) using microfluidic and…
Vertical optofluidic biosensors based on refractive index sensing promise highest sensitivities at smallest area foot-print. Nevertheless, when it comes to large scale fabrication and application of such sensors, cheap and robust platforms…
Today, pipeline networks serve as critical infrastructure for transporting materials such as water, gas, and oil. Modern technologies such as the Internet of Things (IoT), sensor nodes, and inspection robots enable efficient pipeline…
In this paper, we propose a molecular communication system to localize an abnormality in a diffusion based medium. We consider a general setup to perform joint sensing, communication and localization. This setup consists of three types of…
Tracking droplets in microfluidics is a challenging task. The difficulty arises in choosing a tool to analyze general microfluidic videos to infer physical quantities. The state-of-the-art object detector algorithm You Only Look Once (YOLO)…
Flow-based microfluidic biochips are widely used in lab- on-a-chip experiments. In these chips, devices such as mixers and detectors connected by micro-channels execute specific operations. Intermediate fluid samples are saved in storage…
Droplet-based microfluidics has emerged as a powerful technology for the miniaturization and automation of biochemical assays. The replacement of surfactants by nanoparticles as interfacial stabilizers has gained increasing interest.…