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The efficient and fair allocation of limited resources is a classical problem in economics and computer science. In kidney exchanges, a central market maker allocates living kidney donors to patients in need of an organ. Patients and donors…

Artificial Intelligence · Computer Science 2020-05-21 Rachel Freedman , Jana Schaich Borg , Walter Sinnott-Armstrong , John P. Dickerson , Vincent Conitzer

A growing body of work in Ethical AI attempts to capture human moral judgments through simple computational models. The key question we address in this work is whether such simple AI models capture {the critical} nuances of moral…

Human-Computer Interaction · Computer Science 2025-03-04 Vijay Keswani , Vincent Conitzer , Walter Sinnott-Armstrong , Breanna K. Nguyen , Hoda Heidari , Jana Schaich Borg

In response to the pressing challenge of kidney allocation, characterized by growing demands for organs, this research sets out to develop a data-driven solution to this problem, which also incorporates stakeholder values. The primary…

Kidney transplantation is the preferred treatment for end-stage renal disease, yet the scarcity of donors and inefficiencies in allocation systems create major bottlenecks, resulting in prolonged wait times and alarming mortality rates.…

Computer Science and Game Theory · Computer Science 2024-10-15 Sean Berry , Berk Gorgulu , Sait Tunc , Mucahit Cevik , Matthew J Ellis

Alignment methods in moral domains seek to elicit moral preferences of human stakeholders and incorporate them into AI. This presupposes moral preferences as static targets, but such preferences often evolve over time. Proper alignment of…

Human-Computer Interaction · Computer Science 2025-11-14 Vijay Keswani , Cyrus Cousins , Breanna Nguyen , Vincent Conitzer , Hoda Heidari , Jana Schaich Borg , Walter Sinnott-Armstrong

Kidney transplants are sharply overdemanded in the United States. A recent innovation to address organ shortages is a kidney exchange, in which willing but medically incompatible patient-donor pairs swap donors so that two successful…

Computer Science and Game Theory · Computer Science 2019-12-24 Irena Gao

The kidney paired donation (KPD) program provides an innovative solution to overcome incompatibility challenges in kidney transplants by matching incompatible donor-patient pairs and facilitating kidney exchanges. To address unequal access…

Methodology · Statistics 2026-01-21 Mingrui Zhang , Xiaowu Dai , Lexin Li

Balancing fairness and efficiency in resource allocation is a classical economic and computational problem. The price of fairness measures the worst-case loss of economic efficiency when using an inefficient but fair allocation rule; for…

Computer Science and Game Theory · Computer Science 2017-09-11 Duncan C. McElfresh , John P. Dickerson

Medical institutions are considering the use of LLMs in high-stakes clinical decision-making, such as organ allocation. In such sensitive use cases, evaluating fairness is imperative. However, existing evaluation methods often fall short;…

Machine Learning · Computer Science 2026-01-16 Brian Hyeongseok Kim , Hannah Murray , Isabelle Lee , Jason Byun , Joshua Lum , Dani Yogatama , Evi Micha

A kidney exchange program, also called a kidney paired donation program, can be viewed as a repeated, dynamic trading and allocation mechanism. This suggests that a dynamic algorithm for transplant exchange selection may have superior…

Optimization and Control · Mathematics 2023-09-26 Margarida Carvalho , Alison Caulfield , Yi Lin , Adrian Vetta

The rapid integration of Large Language Models (LLMs) in high-stakes decision-making -- such as allocating scarce resources like donor organs -- raises critical questions about their alignment with human moral values. We systematically…

Computers and Society · Computer Science 2026-04-21 John P. Dickerson , Hadi Hosseini , Samarth Khanna , Leona Pierce

In kidney exchange programs, multiple patient-donor pairs each of whom are otherwise incompatible, exchange their donors to receive compatible kidneys. The Kidney Exchange problem is typically modelled as a directed graph where every vertex…

Computer Science and Game Theory · Computer Science 2024-06-17 Arnab Maiti , Palash Dey

The study of matching theory has gained importance recently with applications in Kidney Exchange, House Allocation, School Choice etc. The general theme of these problems is to allocate goods in a fair manner amongst participating agents.…

Computer Science and Game Theory · Computer Science 2020-02-10 Shyam Chandramouli , Jay Sethuraman

Algorithms for exchange of kidneys is one of the key successful applications in market design, artificial intelligence, and operations research. Potent immunosuppressant drugs suppress the body's ability to reject a transplanted organ up to…

Computer Science and Game Theory · Computer Science 2021-03-04 Haris Aziz , Agnes Cseh , John P. Dickerson , Duncan C. McElfresh

The allocation of scarce donor organs constitutes one of the most consequential algorithmic challenges in healthcare. While the field is rapidly transitioning from rigid, rule-based systems to machine learning and data-driven optimization,…

Machine Learning · Computer Science 2026-05-27 Ioannis Anagnostides , Itai Zilberstein , Zachary W. Sollie , Arman Kilic , Tuomas Sandholm

Modern kidney placement incorporates several intelligent recommendation systems which exhibit social discrimination due to biases inherited from training data. Although initial attempts were made in the literature to study algorithmic…

Machine Learning · Computer Science 2024-04-08 Mukund Telukunta , Sukruth Rao , Gabriella Stickney , Venkata Sriram Siddardh Nadendla , Casey Canfield

Regression-based predictive analytics used in modern kidney transplantation is known to inherit biases from training data. This leads to social discrimination and inefficient organ utilization, particularly in the context of a few social…

Human-Computer Interaction · Computer Science 2025-05-13 Mukund Telukunta , Venkata Sriram Siddhardh Nadendla , Morgan Stuart , Casey Canfield

We propose a way in which Kidney exchange can be feasibly, economically and efficiently implemented in Indian medical space, named as Indian Kidney Exchange Program(IKEP) along with Indian specific influence on compatibility and final…

Computer Science and Game Theory · Computer Science 2022-03-16 Arghya Bandyopadhyay , Sajal Mukhopadhyay

Given AI's growing role in modeling and improving decision-making, how and when to present users with feedback is an urgent topic to address. We empirically examined the effect of feedback from false AI on moral decision-making about donor…

Kidney exchange programs have substantially increased transplantation rates but also raise critical concerns about fairness in organ allocation. We propose a novel framework leveraging Data Envelopment Analysis (DEA) to evaluate multiple…

Computers and Society · Computer Science 2025-12-09 Ali Kaazempur-Mofrad , Xiaowu Dai
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