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Survival analysis, time-to-event analysis, is an important problem in healthcare since it has a wide-ranging impact on patients and palliative care. Many survival analysis methods have assumed that the survival data is centrally available…

Machine Learning · Computer Science 2022-07-13 Md Mahmudur Rahman , Sanjay Purushotham

The diversity in disease profiles and therapeutic approaches between hospitals and health professionals underscores the need for patient-centric personalized strategies in healthcare. Alongside this, similarities in disease progression…

Machine Learning · Computer Science 2025-05-23 Navid Seidi , Satyaki Roy , Sajal K. Das , Ardhendu Tripathy

Federated Learning (FL) holds great promise for digital health by enabling collaborative model training without compromising patient data privacy. However, heterogeneity across institutions, lack of sustained reputation, and unreliable…

Machine Learning · Computer Science 2025-05-23 Navid Seidi , Satyaki Roy , Sajal Das

Recent research has shown the potential for neural networks to improve upon classical survival models such as the Cox model, which is widely used in clinical practice. Neural networks, however, typically rely on data that are centrally…

Machine Learning · Computer Science 2022-07-12 Dekai Zhang , Francesca Toni , Matthew Williams

In this study, we address the challenge of survival analysis within heterogeneous patient populations, where traditional reliance on a single regression model such as the Cox proportional hazards (Cox PH) model often falls short.…

Methodology · Statistics 2025-04-15 Ahmad Talafha

Survival analysis often relies on Cox models, assuming both linearity and proportional hazards (PH). This study evaluates machine and deep learning methods that relax these constraints, comparing their performance with penalized Cox models…

Machine Learning · Computer Science 2025-10-21 Ivan Rossi , Flavio Sartori , Cesare Rollo , Giovanni Birolo , Piero Fariselli , Tiziana Sanavia

In multi-center clinical research, privacy regulations often prohibit pooling individual-level records, complicating the analysis of time-to-event data. Current federated survival methods frequently require iterative communication or rely…

Applications · Statistics 2026-03-12 Hyojung Jang , Malcolm Risk , Yaojie Wang , Norrina Bai Allen , Xu Shi , Lili Zhao

We study two foundational problems in distributed survival analysis under federated differential privacy (FDP): estimation of the Cox regression coefficients and of the cumulative baseline hazard functions, allowing for heterogeneous…

Statistics Theory · Mathematics 2026-04-07 Elly K. H. Hung , Yi Yu

Survival analysis is an important research topic with applications in healthcare, business, and manufacturing. One essential tool in this area is the Cox proportional hazards (CPH) model, which is widely used for its interpretability,…

Machine Learning · Computer Science 2024-10-28 Jiachang Liu , Rui Zhang , Cynthia Rudin

Most prediction models that are used in medical research fail to accurately predict health outcomes due to methodological limitations. Using routinely collected patient data, we explore the use of a Cox proportional hazard (PH) model within…

Methodology · Statistics 2019-07-19 John Mbotwa , Marc de Kamps , Paul D. Baxter , Mark S. Gilthorpe

Many application scenarios call for training a machine learning model among multiple participants. Federated learning (FL) was proposed to enable joint training of a deep learning model using the local data in each party without revealing…

Machine Learning · Computer Science 2021-02-12 Kai-Fung Chu , Lintao Zhang

Federated Learning (FL) is a machine learning paradigm where many local nodes collaboratively train a central model while keeping the training data decentralized. This is particularly relevant for clinical applications since patient data…

Recent studies have used speech signals to assess depression. However, speech features can lead to serious privacy concerns. To address these concerns, prior work has used privacy-preserving speech features. However, using a subset of…

Human-Computer Interaction · Computer Science 2022-05-23 Suhas BN , Saeed Abdullah

Although the Cox proportional hazards model is well established and extensively used in the analysis of survival data, the proportional hazards (PH) assumption may not always hold in practical scenarios. The class of semiparametric…

Methodology · Statistics 2025-10-21 Junkai Yin , Yue Zhang , Zhangsheng Yu

Survival analysis or time-to-event analysis aims to model and predict the time it takes for an event of interest to happen in a population or an individual. In the medical context this event might be the time of dying, metastasis,…

Machine Learning · Computer Science 2022-02-09 Shadi Rahimian , Raouf Kerkouche , Ina Kurth , Mario Fritz

Federated learning (FL) is a machine learning paradigm in which distributed local nodes collaboratively train a central model without sharing individually held private data. Existing FL methods either iteratively share local model…

Machine Learning · Computer Science 2023-12-25 Xuan Gong , Shanglin Li , Yuxiang Bao , Barry Yao , Yawen Huang , Ziyan Wu , Baochang Zhang , Yefeng Zheng , David Doermann

Survival analysis is a challenging variation of regression modeling because of the presence of censoring, where the outcome measurement is only partially known, due to, for example, loss to follow up. Such problems come up frequently in…

Machine Learning · Computer Science 2022-06-28 Chirag Nagpal , Steve Yadlowsky , Negar Rostamzadeh , Katherine Heller

Federated Learning (FL) provides a decentralized machine learning approach, where multiple devices or servers collaboratively train a model without sharing their raw data, thus enabling data privacy. This approach has gained significant…

Machine Learning · Computer Science 2025-02-17 Mahad Ali , Curtis Lisle , Patrick W. Moore , Tammer Barkouki , Brian J. Kirkwood , Laura J. Brattain

Federated learning enables building a shared model from multicentre data while storing the training data locally for privacy. In this paper, we present an evaluation (called CXR-FL) of deep learning-based models for chest X-ray image…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Filip Ślazyk , Przemysław Jabłecki , Aneta Lisowska , Maciej Malawski , Szymon Płotka

Survival models are a popular tool for the analysis of time to event data with applications in medicine, engineering, economics, and many more. Advances like the Cox proportional hazard model have enabled researchers to better describe…

Machine Learning · Statistics 2021-02-16 Stefan Groha , Sebastian M Schmon , Alexander Gusev
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