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As compute power increases with time, more involved and larger simulations become possible. However, it gets increasingly difficult to efficiently use the provided computational resources. Especially in particle-based simulations with a…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-08-05 Sebastian Eibl , Ulrich Rüde

In many cellular signaling pathways, key components form clusters at the cell membrane. Although much work has focused on the mechanisms behind such cluster formation, the implications for downstream signaling remain poorly understood.…

Molecular Networks · Quantitative Biology 2012-03-14 Andrew Mugler , Aimee Gotway Bailey , Koichi Takahashi , Pieter Rein ten Wolde

The partitioning of small molecules in cell membranes---a key parameter for pharmaceutical applications---typically relies on experimentally-available bulk partitioning coefficients. Computer simulations provide a structural resolution of…

Soft Condensed Matter · Physics 2017-12-04 Roberto Menichetti , Kiran H. Kanekal , Kurt Kremer , Tristan Bereau

Patchy particles is the name given to a large class of systems of mesoscopic particles characterized by a repulsive core and a discrete number of short-range and highly directional interaction sites. Numerical simulations have contributed…

Soft Condensed Matter · Physics 2018-04-12 Lorenzo Rovigatti , John Russo , Flavio Romano

The difficulty of simulating quantum systems, well-known to quantum chemists, prompted the idea of quantum computation. One can avoid the steep scaling associated with the exact simulation of increasingly large quantum systems on…

The ever increasing demands placed upon machine performance have resulted in the need for more comprehensive particle accelerator modeling. Computer simulations are key to the success of particle accelerators. Many aspects of particle…

Particle filtering is a numerical Bayesian technique that has great potential for solving sequential estimation problems involving non-linear and non-Gaussian models. Since the estimation accuracy achieved by particle filters improves as…

Computation · Statistics 2017-11-22 Jeyarajan Thiyagalingam , Lykourgos Kekempanos , Simon Maskell

Particle filtering is a popular method for inferring latent states in stochastic dynamical systems, whose theoretical properties have been well studied in machine learning and statistics communities. In many control problems, e.g.,…

Machine Learning · Computer Science 2021-07-12 Simon S. Du , Wei Hu , Zhiyuan Li , Ruoqi Shen , Zhao Song , Jiajun Wu

In biomolecular systems (especially all-atom models) with many degrees of freedom such as proteins and nucleic acids, there exist an astronomically large number of local-minimum-energy states. Conventional simulations in the canonical…

Statistical Mechanics · Physics 2010-12-30 Ayori Mitsutake , Yoshiharu Mori , Yuko Okamoto

The Particle-In-Cell (PIC) method for plasma simulation tracks particle phase space information using particle and grid data structures. High computational costs in 2D and 3D device-scale PIC simulations necessitate parallelization, with…

Computational Physics · Physics 2025-06-27 Libn Varghese , Bhaskar Chaudhury , Miral Shah , Mainak Bandyopadhyay

The recently developed energy conserving semi-implicit method (ECsim) for PIC simulation is applied to multiple scale problems where the electron-scale physics needs to be only partially retained and the interest is on the macroscopic or…

Computational Physics · Physics 2017-05-24 Giovanni Lapenta , Diego Gonzalez-Herrero , Elisabetta Boella

The quasi-neutral hybrid particle-in-cell algorithm with kinetic ions and fluid electrons is a popular model to study multi-scale problems in laboratory, space, and astrophysical plasmas. Here, it is shown that the treatment of ions as…

Plasma Physics · Physics 2020-08-26 A. Stanier , L. Chacon , A. Le

Particle-In-Cell (PIC) codes are broadly applied to the kinetic simulation of plasmas, from laser-matter interaction to astrophysics. Their heavy simulation cost can be mitigated by using the Single Instruction Multiple Data (SIMD)…

Algorithms for simulating complex physical systems or solving difficult optimization problems often resort to an annealing process. Rather than simulating the system at the temperature of interest, an annealing algorithm starts at a…

Computational Physics · Physics 2015-04-02 Michael Habeck

Particle-in-Cell (PIC) simulations are fundamental to plasma physics but often suffer from limited scalability due to particle-grid interaction bottlenecks and particle redistribution costs. Specifically, the particle-grid interaction…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-22 Yizhuo Rao , Xingjian Cui , Shangzhi Pang , Jiabin Xie , Guangnan Feng , Jinhui Wei , Ziyan Zhang , Languang Gao , Zhenyu Wang , Zhiguang Chen , Yutong Lu

Particle filters are applicable to a wide range of nonlinear, non-Gaussian state-space models and have already been applied to a variety of problems. However, there is a problem in the calculation of smoothed distributions, where particles…

Computation · Statistics 2024-05-16 G. Kitagawa

In this paper, we present different types of integrators for electro-magnetic particle-in-cell (PIC) methods. While the integrator is an important tool of the PIC methods, it is necessary to characterize the different conservation…

Numerical Analysis · Mathematics 2014-11-05 Juergen Geiser , Frederik Riedel

Particle-in-cell with Monte Carlo collisions (PIC/MCC) is a fully kinetic, particle based numerical simulation method with increasing popularity in the field of low temperature gas discharge physics. Already in its simplest form…

Plasma Physics · Physics 2022-06-15 Mate Vass , Peter Palla , Peter Hartmann

Owing to the computational complexity of electronic structure algorithms running on classical digital computers, the range of molecular systems amenable to simulation remains tightly circumscribed even after many decades of work. Quantum…

Quantum Physics · Physics 2022-05-18 Alexis Ralli , Michael I. Williams , Peter V. Coveney

Normal molecular dynamics simulations are usually unable to simulate chemical reactions due to the low probability of forming the transition state. Therefore, enhanced sampling methods are implemented to accelerate the occurrence of…

Chemical Physics · Physics 2022-10-14 Yi Sun , Xu Han , Lijiang Yang