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Elastic properties of arteries have long been recognized as playing a major role in the cardiovascular system. However, non-invasive in vivo assessment of local arterial stiffness remains challenging and imprecise as current techniques rely…
Computational fluid dynamics (CFD) is a valuable tool for personalised, non-invasive evaluation of hemodynamics in arteries, but its complexity and time-consuming nature prohibit large-scale use in practice. Recently, the use of deep…
Spatial patterns of elevated wall shear stress and pressure due to blood flow past aortic stenosis (AS) are studied using GPU-accelerated patient-specific computational fluid dynamics. Three cases of moderate AS, one with a dilated…
Wall shear stress quantification is fundamental in fluid dynamics but remains challenging in wind-tunnel experiments. Sensor-based methods offer high accuracy but lack spatial resolution for capturing complex three-dimensional effects.…
Quantification of cerebral white matter hyperintensities (WMH) of presumed vascular origin is of key importance in many neurological research studies. Currently, measurements are often still obtained from manual segmentations on brain MR…
The rheology of suspensions showing discontinuous shear thickening (DST) is well documented in conventional rheometer with rotating tools, but their study in capillary flow is still lacking. We present results obtained in a homemade…
We report a new method to measure the velocity of a fluid in the vicinity of a wall. The method, that we call Particle-Shadow Tracking (PST), simply consists in seeding the fluid with a small number of fine tracer particles of density close…
The instantaneous two-dimensional wall shear rate is assessed through an inverse problem using mass transfer data from a three-segment electrodiffusion probe. The method is validated numerically in complex flow conditions involving (i) high…
The measurement of shear stress acting on a biologically relevant surface is a challenging problem, particularly in the complex environment of, for example, the vasculature. While an experimental method for the direct detection of wall…
Mechanical stresses in soft materials across different length scales play a fundamental role in understanding the function of biological systems and in the use of artificial materials for engineering soft machines and biomedical devices.…
Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…
The accurate quantification of wall-shear stress dynamics is of substantial importance for various applications in fundamental and applied research, spanning areas from human health to aircraft design and optimization. Despite significant…
We propose a Navier-Stokes-driven analysis of the mean and fluctuating wall shear stress (WSS) applied to turbulent channel flow data from direct numerical simulations at friction Reynolds numbers up to $Re_\tau\approx 2000$. Starting from…
White matter hyperintensities (WMH) are a hallmark of cerebrovascular disease and multiple sclerosis. Automated WMH segmentation methods enable quantitative analysis via estimation of total lesion load, spatial distribution of lesions, and…
In share wave elastography (SWE), the aim is to measure the velocity of shear waves, however unwanted compression waves and bulk tissue motion pose challenges in evaluating tissue stiffness. Conventional approaches often struggle to…
The objectives were to develop a novel three-dimensional technology for imaging naturally occurring shear wave (SW) propagation, demonstrate feasibility on human volunteers and quantify SW velocity in different propagation directions.…
This study investigates the influence of aneurysm evolution on hemodynamic characteristics within the sac region. Using computational fluid dynamics (CFD), blood flow through the parent vessel and aneurysm sac was analyzed to assess the…
Mental stress is a prevalent condition that can have negative impacts on one's health. Early detection and treatment are crucial for preventing related illnesses and maintaining overall wellness. This study presents a new method for…
Arterial biomechanical indicators have long been recognized as fundamental contributors to the physiology and pathology of cardiovascular systems. Probing the multiple biomechanical parameters of arteries simultaneously at different time…
We numerically investigate the influence of flow development on secondary flow patterns and subsequent wall shear stress distributions in a curved artery model, and we compute vascular metrics commonly used to assess variations in blood…