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With their growing capabilities, generative large language models (LLMs) are being increasingly investigated for complex medical tasks. However, their effectiveness in real-world clinical applications remains underexplored. To address this,…

Computation and Language · Computer Science 2026-01-27 Paul Grundmann , Dennis Fast , Jan Frick , Thomas Steffek , Felix Gers , Wolfgang Nejdl , Alexander Löser

A main challenge of data-driven sciences is how to make maximal use of the progressively expanding databases of experimental datasets in order to keep research cumulative. We introduce the idea of a modeling-based dataset retrieval engine…

Quantitative Methods · Quantitative Biology 2015-06-19 Ali Faisal , Jaakko Peltonen , Elisabeth Georgii , Johan Rung , Samuel Kaski

Machine learning is bringing a paradigm shift to healthcare by changing the process of disease diagnosis and prognosis in clinics and hospitals. This development equips doctors and medical staff with tools to evaluate their hypotheses and…

Worldwide, several cases go undiagnosed due to poor healthcare support in remote areas. In this context, a centralized system is needed for effective monitoring and analysis of the medical records. A web-based patient diagnostic system is a…

Computer Vision and Pattern Recognition · Computer Science 2021-07-06 Harish Rajora , Narinder Singh Punn , Sanjay Kumar Sonbhadra , Sonali Agarwal

With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

Quantitative Methods · Quantitative Biology 2020-07-03 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

We report applications of Convolutional Neural Networks (CNN) to multi-classification classification of a large medical data set. We discuss in detail how changes in the CNN model and the data pre-processing impact the classification…

Machine Learning · Computer Science 2020-12-29 YuanZheng Hu , Marina Sokolova

Improving the precision of heart diseases detection has been investigated by many researchers in the literature. Such improvement induced by the overwhelming health care expenditures and erroneous diagnosis. As a result, various…

Computers and Society · Computer Science 2018-03-29 Israa Ahmed Zriqat , Ahmad Mousa Altamimi , Mohammad Azzeh

Disease-symptom datasets are significant and in demand for medical research, disease diagnosis, clinical decision-making, and AI-driven health management applications. These datasets help identify symptom patterns associated with specific…

Computation and Language · Computer Science 2025-09-09 Abdullah Al Shafi , Rowzatul Zannat , Abdul Muntakim , Mahmudul Hasan

The success of deep learning is largely due to the availability of large amounts of training data that cover a wide range of examples of a particular concept or meaning. In the field of medicine, having a diverse set of training data on a…

Artificial Intelligence · Computer Science 2023-05-02 Edward Y. Chang

High throughput genome sequencing technologies such as RNA-Seq and Microarray have the potential to transform clinical decision making and biomedical research by enabling high-throughput measurements of the genome at a granular level.…

Joint models for longitudinal and time-to-event data are commonly used in longitudinal studies to forecast disease trajectories over time. While there are many advantages to joint modeling, the standard forms suffer from limitations that…

Machine Learning · Statistics 2019-09-09 Bryan Lim , Mihaela van der Schaar

Traditional machine learning methods face two main challenges in dealing with healthcare predictive analytics tasks. First, the high-dimensional nature of healthcare data needs labor-intensive and time-consuming processes to select an…

Machine Learning · Computer Science 2022-09-16 Mohammad Amin Morid , Olivia R. Liu Sheng , Joseph Dunbar

The remarkable success of deep learning in recent years has prompted applications in medical image classification and diagnosis tasks. While classification models have demonstrated robustness in classifying simpler datasets like MNIST or…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Sushmita Sarker , Prithul Sarker , George Bebis , Alireza Tavakkoli

Accurate breast lesion risk estimation can significantly reduce unnecessary biopsies and help doctors decide optimal treatment plans. Most existing computer-aided systems rely solely on mammogram features to classify breast lesions. While…

Image and Video Processing · Electrical Eng. & Systems 2021-08-24 Hung Q. Vo , Pengyu Yuan , Tiancheng He , Stephen T. C. Wong , Hien V. Nguyen

The increased availability of medical data has significantly impacted healthcare by enabling the application of machine / deep learning approaches in various instances. However, medical datasets are usually small and scattered across…

We consider a problem of data integration. Consider determining which genes affect a disease. The genes, which we call predictor objects, can be measured in different experiments on the same individual. We address the question of finding…

Machine Learning · Statistics 2016-10-04 Xin Gao , Raymond J. Carroll

Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is…

Machine Learning · Statistics 2016-08-17 Joseph Futoma , Mark Sendak , C. Blake Cameron , Katherine Heller

Accurate disease detection is of paramount importance for effective medical treatment and patient care. However, the process of disease detection is often associated with extensive medical testing and considerable costs, making it…

Machine Learning · Computer Science 2025-12-10 Haokun Zhao , Yingzhe Bai , Qingyang Xu , Lixin Zhou , Jianxin Chen , Jicong Fan

Clinical trials are a systematic endeavor to assess the safety and efficacy of new drugs or treatments. Conducting such trials typically demands significant financial investment and meticulous planning, highlighting the need for accurate…

Machine Learning · Computer Science 2025-11-03 Tien Huu Do , Antoine Masquelier , Nae Eoun Lee , Jonathan Crowther

As artificial intelligence systems move toward clinical deployment, ensuring reliable prediction behavior is fundamental for safety-critical decision-making tasks. One proposed safeguard is selective prediction, where models can defer…

Machine Learning · Computer Science 2026-05-25 L. Julián Lechuga López , Farah E. Shamout , Tim G. J. Rudner