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The ubiquitous $3/4$ metabolic scaling exponent, known as Kleiber's law, has long been attributed to the minimization of viscous dissipation within fractal transport networks. In this paper, we invert this standard narrative, demonstrating…

Biological Physics · Physics 2026-04-14 Riccardo Marchesi

The origin of allometric scaling patterns that are multiples of 1/4 has long fascinated biologists. While not universal, scaling relationships with exponents that are close to multiples of 1/4 are common and have been described in all major…

Quantitative Methods · Quantitative Biology 2015-07-29 Charles A. Price , Paul Drake , Erik J. Veneklaas , Michael Renton

This paper investigates the role of size in biological organisms. More specifically, how the energy demand, expressed by the metabolic rate, changes according to the mass of an organism. Empirical evidence suggests a power-law relation…

Other Quantitative Biology · Quantitative Biology 2021-05-05 Fabiano L. Ribeiro , William R. L. S. Pereira

A set of general allometric scaling laws is derived for different systems represented by tree networks. The formulation postulates self-similar networks with an arbitrary number of branches developed in each generation, and with an…

Physics and Society · Physics 2017-10-06 L. Zavala Sansón , A. González-Villanueva

A central debate in biology has been the allometric scaling of metabolic rate. Kleiber's observation that animals' basal metabolic rate scales to the 3/4-power of body mass (Kleiber's rule) has been the prevailing hypothesis in the last…

Biological Physics · Physics 2015-10-01 Jinkui Zhao

Allometric scaling laws, such as Kleiber's law for metabolic rate, highlight how efficiency emerges with size across living systems. The brain, with its characteristic sublinear scaling of activity, has long posed a puzzle: why do larger…

Neurons and Cognition · Quantitative Biology 2026-05-26 Tiago S. A. N. Simões , José S. Andrade , Hans J. Herrmann , Stefano Zapperi , Lucilla de Arcangelis

The origin of allometric scaling of metabolic rate is a long-standing question in biology. Several models have been proposed for explaining the origin; however, they have advantages and disadvantages. In particular, previous models only…

Other Quantitative Biology · Quantitative Biology 2015-02-23 Kazuhiro Takemoto

One of the most fundamental rules in metabolic ecology is the allometric equation, which is a power-law scaling that describes the connection between body measurements and body size. The biological dynamics of this essentially empirical…

Other Quantitative Biology · Quantitative Biology 2024-05-14 Jia-Xu Han , Zhuangdong Bai , Rui-Wu Wang

The quarter power allometric scaling of mammalian metabolic rate is largely regarded as a universal law of biology. However, it is well known that cell cultures do not obey this law. The current thinking is that were in-vitro cultures to…

Tissues and Organs · Quantitative Biology 2017-01-23 Arti Ahluwalia

The prevailing theory for metabolic scaling is based on area-preserved, space-filling fractal vascular networks. However, it's known both theoretically and experimentally that animals' vascular systems obey Murray's cubic branching law.…

Quantitative Methods · Quantitative Biology 2022-05-31 Jinkui Zhao

At the basic geometric level, the distribution networks carrying vital materials in living organisms, and the units such as the nephrons and alveoli, form a scaling structure named here the site model. This unified view of the allometry of…

Tissues and Organs · Quantitative Biology 2007-05-23 Walton R. Gutierrez

The origin and shape of metabolic scaling has been controversial since Kleiber found that basal metabolic rate of animals seemed to vary as a power law of their body mass with exponent 3/4, instead of 2/3, as a surface-to-volume argument…

An analogy between the fractal nature of networks of arteries and that of systems of rivers has been drawn in the previous works. However, the deep structure of the hierarchy of blood vessels has not yet been revealed. This paper is devoted…

Physics and Society · Physics 2018-12-19 Yanguang Chen

Allometric scaling is one of the most pervasive laws in biology. Its origin, however, is still a matter of dispute. Recent studies have established that maximum metabolic rate scales with an exponent larger than that found for basal…

Biological Physics · Physics 2007-05-23 Lauro A. Barbosa , Guilherme J. M. Garcia , Jafferson K. L. da Silva

An ecological flow network is a weighted directed graph in which nodes are species, edges are "who eats whom" relationships and weights are rates of energy or nutrients transfer between species. Allometric scaling is a ubiquitous feature…

Populations and Evolution · Quantitative Biology 2013-09-24 Jiang Zhang , Lingfei Wu

Scientists have long sought to understand how vascular networks supply blood and oxygen to cells throughout the body. Recent work focuses on principles that constrain how vessel size changes through branching generations from the aorta to…

Tissues and Organs · Quantitative Biology 2015-09-10 Mitchell G Newberry , Daniel B Ennis , Van M Savage

The growth and scaling of organs is a fundamental aspect of animal development. However, how organs grow to the right size and shape required by physiological demands, remains largely unknown. Here, we provide a framework combining theory…

Biological Physics · Physics 2026-02-04 Christian Hanauer , Amrutha Palavalli , Baiqun An , Efe Ilker , Jochen C. Rink , Frank Jülicher

Individual resource intake rates are known to depend on both individual body size and resource availability. Here, we have developed a model to integrate these two drivers, accounting explicitly for the scaling of perceived resource…

Populations and Evolution · Quantitative Biology 2010-02-18 Alberto Basset , Francesco Paparella , Francesco Cozzoli

We study the breaking of ergodicity measured in terms of return probability in the evolution of a quantum state of a spin chain. In the non ergodic phase a quantum state evolves in a much smaller fraction of the Hilbert space than would be…

Strongly Correlated Electrons · Physics 2013-02-28 Andrea De Luca , Antonello Scardicchio

We study ergodicity breaking in the clean Bose-Hubbard chain for small hopping strength. We see the existence of a non-ergodic regime by means of indicators as the half-chain entanglement entropy of the eigenstates, the average level…

Quantum Gases · Physics 2021-03-04 Angelo Russomanno , Michele Fava , Rosario Fazio
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