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There is currently a debate within the neuroscience community over the likelihood of the brain performing backpropagation (BP). To better mimic the brain, training a network \textit{one layer at a time} with only a "single forward pass" has…

Machine Learning · Statistics 2022-02-09 Chieh Wu , Aria Masoomi , Arthur Gretton , Jennifer Dy

Backpropagation of error (backprop) is a powerful algorithm for training machine learning architectures through end-to-end differentiation. However, backprop is often criticised for lacking biological plausibility. Recently, it has been…

Machine Learning · Computer Science 2020-10-07 Beren Millidge , Alexander Tschantz , Christopher L. Buckley

The neural plausibility of backpropagation has long been disputed, primarily for its use of non-local weight transport $-$ the biologically dubious requirement that one neuron instantaneously measure the synaptic weights of another. Until…

Neurons and Cognition · Quantitative Biology 2020-06-26 Daniel Kunin , Aran Nayebi , Javier Sagastuy-Brena , Surya Ganguli , Jonathan M. Bloom , Daniel L. K. Yamins

Generalization to out-of-distribution (OOD) circumstances after training remains a challenge for artificial agents. To improve the robustness displayed by plastic Hebbian neural networks, we evolve a set of Hebbian learning rules, where…

Neural and Evolutionary Computing · Computer Science 2021-04-19 Joachim Winther Pedersen , Sebastian Risi

There is currently a debate within the neuroscience community over the likelihood of the brain performing backpropagation (BP). To better mimic the brain, training a network $\textit{one layer at a time}$ with only a "single forward pass"…

Machine Learning · Statistics 2022-02-10 Chieh Wu , Aria Masoomi , Arthur Gretton , Jennifer Dy

Traditional backpropagation of error, though a highly successful algorithm for learning in artificial neural network models, includes features which are biologically implausible for learning in real neural circuits. An alternative called…

Machine Learning · Computer Science 2020-11-06 Nasir Ahmad , Marcel A. J. van Gerven , Luca Ambrogioni

A fundamental aspect of learning in biological neural networks is the plasticity property which allows them to modify their configurations during their lifetime. Hebbian learning is a biologically plausible mechanism for modeling the…

Neural and Evolutionary Computing · Computer Science 2021-03-16 Anil Yaman , Giovanni Iacca , Decebal Constantin Mocanu , Matt Coler , George Fletcher , Mykola Pechenizkiy

Despite superior performance on many computer vision tasks, deep convolution neural networks are well known to be compressed on devices that have resource constraints. Most existing network pruning methods require laborious human efforts…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Xiawu Zheng , Yuexiao Ma , Teng Xi , Gang Zhang , Errui Ding , Yuchao Li , Jie Chen , Yonghong Tian , Rongrong Ji

Despite its great success, backpropagation has certain limitations that necessitate the investigation of new learning methods. In this study, we present a biologically plausible local learning rule that improves upon Hebb's well-known…

Neural and Evolutionary Computing · Computer Science 2022-12-27 Hongchao Zhou

An artificial neural network can be trained by uniformly broadcasting a reward signal to units that implement a REINFORCE learning rule. Though this presents a biologically plausible alternative to backpropagation in training a network, the…

Machine Learning · Computer Science 2021-12-23 Stephen Chung

Hebbian learning is a key principle underlying learning in biological neural networks. We relate a Hebbian spike-timing-dependent plasticity rule to noisy gradient descent with respect to a non-convex loss function on the probability…

Machine Learning · Computer Science 2026-01-14 Niklas Dexheimer , Sascha Gaudlitz , Johannes Schmidt-Hieber

In a physical neural system, backpropagation is faced with a number of obstacles including: the need for labeled data, the violation of the locality learning principle, the need for symmetric connections, and the lack of modularity.…

Machine Learning · Computer Science 2021-07-23 Mohammadamin Tavakoli , Peter Sadowski , Pierre Baldi

A recent breakthrough in biologically-plausible normative frameworks for dimensionality reduction is based upon the similarity matching cost function and the low-rank matrix approximation problem. Despite clear biological interpretation,…

Neurons and Cognition · Quantitative Biology 2025-06-09 Veronica Centorrino , Francesco Bullo , Giovanni Russo

In this theory paper, we investigate training deep neural networks (DNNs) for classification via minimizing the information bottleneck (IB) functional. We show that the resulting optimization problem suffers from two severe issues: First,…

Machine Learning · Computer Science 2020-08-10 Rana Ali Amjad , Bernhard C. Geiger

In this article we intoduce a novel stochastic Hebb-like learning rule for neural networks that is neurobiologically motivated. This learning rule combines features of unsupervised (Hebbian) and supervised (reinforcement) learning and is…

Disordered Systems and Neural Networks · Physics 2009-11-11 Frank Emmert-Streib

Hebbian learning is a biological principle that intuitively describes how neurons adapt their connections through repeated stimuli. However, when applied to machine learning, it suffers serious issues due to the unconstrained updates of the…

Machine Learning · Computer Science 2025-10-23 Shikuang Deng , Jiayuan Zhang , Yuhang Wu , Ting Chen , Shi Gu

Developing reliable mechanisms for continuous local learning is a central challenge faced by biological and artificial systems. Yet, how the environmental factors and structural constraints on the learning network influence the optimal…

Neurons and Cognition · Quantitative Biology 2024-03-21 Emmanouil Giannakakis , Sina Khajehabdollahi , Anna Levina

Reservoir computing is a powerful tool to explain how the brain learns temporal sequences, such as movements, but existing learning schemes are either biologically implausible or too inefficient to explain animal performance. We show that a…

Neurons and Cognition · Quantitative Biology 2019-10-24 Roman Pogodin , Dane Corneil , Alexander Seeholzer , Joseph Heng , Wulfram Gerstner

Neuroscientists have long criticised deep learning algorithms as incompatible with current knowledge of neurobiology. We explore more biologically plausible versions of deep representation learning, focusing here mostly on unsupervised…

Machine Learning · Computer Science 2016-08-10 Yoshua Bengio , Dong-Hyun Lee , Jorg Bornschein , Thomas Mesnard , Zhouhan Lin

Bio-inspired learning has been gaining popularity recently given that Backpropagation (BP) is not considered biologically plausible. Many algorithms have been proposed in the literature which are all more biologically plausible than BP.…

Machine Learning · Computer Science 2023-08-31 Manas Gupta , Sarthak Ketanbhai Modi , Hang Zhang , Joon Hei Lee , Joo Hwee Lim