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A phylogenetic tree is an important way in Bioinformatics to find the evolutionary relationship among biological species. In this research, a proposed model is described for the estimation of a phylogenetic tree for a given set of data. To…

Populations and Evolution · Quantitative Biology 2025-09-03 S M Rafiuddin

Although distance measures are used in many machine learning algorithms, the literature on the context-independent selection and evaluation of distance measures is limited in the sense that prior knowledge is used. In cluster analysis,…

Machine Learning · Computer Science 2021-08-24 Michael C. Thrun

Phylogenetic trees summarize evolutionary relationships between organisms, and tools to analyze collections of phylogenetic trees enable contrasts between different genes' ancestry. The BHV metric space has enabled the analysis of…

Quantitative Methods · Quantitative Biology 2026-04-24 Maria Alejandra Valdez Cabrera , Amy D Willis

The algebraic properties of flattenings and subflattenings provide direct methods for identifying edges in the true phylogeny -- and by extension the complete tree -- using pattern counts from a sequence alignment. The relatively small…

Populations and Evolution · Quantitative Biology 2022-05-06 Joshua Stevenson , Barbara Holland , Michael Charleston , Jeremy Sumner

The inference of phylogenetic networks, which model complex evolutionary processes including hybridization and gene flow, remains a central challenge in evolutionary biology. Until now, statistically consistent inference methods have been…

Populations and Evolution · Quantitative Biology 2025-10-14 Niels Holtgrefe , Elizabeth S. Allman , Hector Baños , Leo van Iersel , Vincent Moulton , John A. Rhodes , Kristina Wicke

Hierarchical clustering is a popular unsupervised data analysis method. For many real-world applications, we would like to exploit prior information about the data that imposes constraints on the clustering hierarchy, and is not captured by…

Data Structures and Algorithms · Computer Science 2018-07-17 Vaggos Chatziafratis , Rad Niazadeh , Moses Charikar

Currently, data-driven discovery in biological sciences resides in finding segmentation strategies in multivariate data that produce sensible descriptions of the data. Clustering is but one of several approaches and sometimes falls short…

Quantitative Methods · Quantitative Biology 2022-08-12 Richard Tjörnhammar

Time series, as one of the most fundamental representations of sequential data, has been extensively studied across diverse disciplines, including computer science, biology, geology, astronomy, and environmental sciences. The advent of…

Machine Learning · Computer Science 2024-12-31 John Paparrizos , Fan Yang , Haojun Li

We propose a nearest neighbor based clustering algorithm that results in a naturally defined hierarchy of clusters. In contrast to the agglomerative and divisive hierarchical clustering algorithms, our approach is not dependent on the…

Data Structures and Algorithms · Computer Science 2022-03-16 Kaan Gokcesu , Hakan Gokcesu

We present a technique for clustering categorical data by generating many dissimilarity matrices and averaging over them. We begin by demonstrating our technique on low dimensional categorical data and comparing it to several other…

Machine Learning · Statistics 2017-09-20 Saeid Amiri , Bertrand Clarke , Jennifer Clarke

Pathogen genome data offers valuable structure for spatial models, but its utility is limited by incomplete sequencing coverage. We propose a probabilistic framework for inferring genetic distances between unsequenced cases and known…

Genomics · Quantitative Biology 2025-09-10 Haley Stone , Jing Du , Hao Xue , Matthew Scotch , David Heslop , Andreas Züfle , Chandini Raina MacIntyre , Flora Salim

Clustering is a common technique for statistical data analysis, which is used in many fields, including machine learning, data mining, pattern recognition, image analysis and bioinformatics. Clustering is the process of grouping similar…

Data Structures and Algorithms · Computer Science 2012-05-08 T. Soni Madhulatha

A hierarchical scheme for clustering data is presented which applies to spaces with a high number of dimension ($N_{_{D}}>3$). The data set is first reduced to a smaller set of partitions (multi-dimensional bins). Multiple clustering…

Data Analysis, Statistics and Probability · Physics 2017-10-16 Kevin McIlhany , Stephen Wiggins

In this work we seek clusters of genomic words in human DNA by studying their inter-word lag distributions. Due to the particularly spiked nature of these histograms, a clustering procedure is proposed that first decomposes each…

Applications · Statistics 2021-01-13 Ana Helena Tavares , Jakob Raymaekers , Peter J. Rousseeuw , Paula Brito , Vera Afreixo

In machine learning and data mining, Cluster analysis is one of the most widely used unsupervised learning technique. Philosophy of this algorithm is to find similar data items and group them together based on any distance function in…

Machine Learning · Statistics 2018-10-09 Kumarjit Pathak , Jitin Kapila

Many methods have been developed for data clustering, such as k-means, expectation maximization and algorithms based on graph theory. In this latter case, graphs are generally constructed by taking into account the Euclidian distance as a…

Data Analysis, Statistics and Probability · Physics 2011-01-27 Francisco A. Rodrigues , Guilherme Ferraz de Arruda , Luciano da Fontoura Costa

Clustering is an unsupervised machine learning methodology where unlabeled elements/objects are grouped together aiming to the construction of well-established clusters that their elements are classified according to their similarity. The…

Machine Learning · Statistics 2023-10-20 Dimitrios Saligkaras , Vasileios E. Papageorgiou

Pattern comparison represents a fundamental and crucial aspect of scientific modeling, artificial intelligence, and pattern recognition. Three main approaches have typically been applied for pattern comparison: (i) distances; (ii)…

Physics and Society · Physics 2024-07-12 Alexandre Benatti , Luciano da F. Costa

Clustering algorithms are one of the main analytical methods to detect patterns in unlabeled data. Existing clustering methods typically treat samples in a dataset as points in a metric space and compute distances to group together similar…

Machine Learning · Computer Science 2021-10-12 Tarek Naous , Srinjay Sarkar , Abubakar Abid , James Zou

Correlations between two variables of a high-dimensional system can be indicative of an underlying interaction, but can also result from indirect effects. Inverse Ising inference is a method to distinguish one from the other. Essentially,…

Populations and Evolution · Quantitative Biology 2014-12-10 Benedikt Obermayer , Erel Levine