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We here present SIMLR (Single-cell Interpretation via Multi-kernel LeaRning), an open-source tool that implements a novel framework to learn a sample-to-sample similarity measure from expression data observed for heterogenous samples. SIMLR…

Genomics · Quantitative Biology 2018-01-22 Bo Wang , Daniele Ramazzotti , Luca De Sano , Junjie Zhu , Emma Pierson , Serafim Batzoglou

A significant challenge to make learning techniques more suitable for general purpose use is to move beyond i) complete supervision, ii) low dimensional data, iii) a single task and single view per instance. Solving these challenges allows…

Machine Learning · Computer Science 2012-02-07 Buyue Qian , Xiang Wang , Ian Davidson

Large language models (LLMs) have shown promising capabilities in visually interpreting medical time-series data. However, their general-purpose design can limit domain-specific precision, and the proprietary nature of many models poses…

Artificial Intelligence · Computer Science 2025-07-22 Huayu Li , Zhengxiao He , Xiwen Chen , Ci Zhang , Stuart F. Quan , William D. S. Killgore , Shu-Fen Wung , Chen X. Chen , Geng Yuan , Jin Lu , Ao Li

We present a neural-field-based large-scale reconstruction system that fuses lidar and vision data to generate high-quality reconstructions that are geometrically accurate and capture photo-realistic textures. This system adapts the…

Robotics · Computer Science 2025-02-18 Yifu Tao , Yash Bhalgat , Lanke Frank Tarimo Fu , Matias Mattamala , Nived Chebrolu , Maurice Fallon

Many learning algorithms such as kernel machines, nearest neighbors, clustering, or anomaly detection, are based on the concept of 'distance' or 'similarity'. Before similarities are used for training an actual machine learning model, we…

Low-dimensional embeddings for data from disparate sources play critical roles in multi-modal machine learning, multimedia information retrieval, and bioinformatics. In this paper, we propose a supervised dimensionality reduction method…

Machine Learning · Computer Science 2021-01-15 Yanjun Li , Bihan Wen , Hao Cheng , Yoram Bresler

The continually increasing number of complex datasets each year necessitates ever improving machine learning methods for robust and accurate categorization of these data. This paper introduces Random Multimodel Deep Learning (RMDL): a new…

Machine Learning · Computer Science 2018-06-01 Kamran Kowsari , Mojtaba Heidarysafa , Donald E. Brown , Kiana Jafari Meimandi , Laura E. Barnes

Deep metric learning (DML) is a cornerstone of many computer vision applications. It aims at learning a mapping from the input domain to an embedding space, where semantically similar objects are located nearby and dissimilar objects far…

Computer Vision and Pattern Recognition · Computer Science 2021-09-10 Artsiom Sanakoyeu , Pingchuan Ma , Vadim Tschernezki , Björn Ommer

Multimodal information retrieval (MMIR) has gained attention for its flexibility in handling text, images, or mixed queries and candidates. Recent breakthroughs in multimodal large language models (MLLMs) boost MMIR performance by…

Information Retrieval · Computer Science 2026-02-27 Dawei Su , Dongsheng Wang

Biological multimodal large language models (MLLMs) have emerged as powerful foundation models for scientific discovery. However, existing models are specialized to a single modality, limiting their ability to solve inherently cross-modal…

Machine Learning · Computer Science 2026-03-17 Wonbin Lee , Dongki Kim , Sung Ju Hwang

Radiologists must utilize multiple modal images for tumor segmentation and diagnosis due to the limitations of medical imaging and the diversity of tumor signals. This leads to the development of multimodal learning in segmentation.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Chuyun Shen , Wenhao Li , Haoqing Chen , Xiaoling Wang , Fengping Zhu , Yuxin Li , Xiangfeng Wang , Bo Jin

The Classification of medical images and illustrations in the literature aims to label a medical image according to the modality it was produced or label an illustration according to its production attributes. It is an essential and…

Computer Vision and Pattern Recognition · Computer Science 2017-06-29 Jianpeng Zhang , Yong Xia , Qi Wu , Yutong Xie

Manifold learning (ML) aims to seek low-dimensional embedding from high-dimensional data. The problem is challenging on real-world datasets, especially with under-sampling data, and we find that previous methods perform poorly in this case.…

Machine Learning · Computer Science 2022-07-27 Zelin Zang , Siyuan Li , Di Wu , Ge Wang , Lei Shang , Baigui Sun , Hao Li , Stan Z. Li

Identifying relationships between molecular variations and their clinical presentations has been challenged by the heterogeneous causes of a disease. It is imperative to unveil the relationship between the high dimensional molecular…

Methodology · Statistics 2021-09-02 Wennan Chang , Changlin Wan , Yong Zang , Chi Zhang , Sha Cao

Model merging combines multiple models into a single model with aggregated capabilities, making it a powerful tool for large language model (LLM) development. However, scaling model merging is challenging: performance depends on the choice…

Machine Learning · Computer Science 2026-02-03 Oliver Bolton , Aakanksha , Arash Ahmadian , Sara Hooker , Marzieh Fadaee , Beyza Ermis

Distance Metric Learning (DML) seeks to learn a discriminative embedding where similar examples are closer, and dissimilar examples are apart. In this paper, we address the problem of Semi-Supervised DML (SSDML) that tries to learn a metric…

Machine Learning · Computer Science 2021-05-12 Ujjal Kr Dutta , Mehrtash Harandi , Chellu Chandra Sekhar

Multi-label Recognition (MLR) involves assigning multiple labels to each data instance in an image, offering advantages over single-label classification in complex scenarios. However, it faces the challenge of annotating all relevant…

Machine Learning · Computer Science 2025-06-03 Ruhui Zhang , Hezhe Qiao , Pengcheng Xu , Mingsheng Shang , Lin Chen

Multi-label classification is an important learning problem with many applications. In this work, we propose a principled similarity-based approach for multi-label learning called SML. We also introduce a similarity-based approach for…

Machine Learning · Statistics 2017-10-31 Ryan A. Rossi , Nesreen K. Ahmed , Hoda Eldardiry , Rong Zhou

How do the neural networks distinguish two images? It is of critical importance to understand the matching mechanism of deep models for developing reliable intelligent systems for many risky visual applications such as surveillance and…

Computer Vision and Pattern Recognition · Computer Science 2021-08-13 Wenliang Zhao , Yongming Rao , Ziyi Wang , Jiwen Lu , Jie Zhou

Sequential recommendation (SR) systems have evolved significantly over the past decade, transitioning from traditional collaborative filtering to deep learning approaches and, more recently, to large language models (LLMs). While the…

Information Retrieval · Computer Science 2024-12-31 Yucong Luo , Qitao Qin , Hao Zhang , Mingyue Cheng , Ruiran Yan , Kefan Wang , Jie Ouyang
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