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Recent advancements in deep learning for automated image processing and classification have accelerated many new applications for medical image analysis. However, most deep learning applications have been developed using reconstructed,…
Multi-material decomposition (MMD) enables quantitative reconstruction of tissue compositions in the human body, supporting a wide range of clinical applications. However, traditional MMD typically requires spectral CT scanners and…
X-ray Computed Tomography (CT) is one of the most important diagnostic imaging techniques in clinical applications. Sparse-view CT imaging reduces the number of projection views to a lower radiation dose and alleviates the potential risk of…
Deep-neural-network-based image reconstruction has demonstrated promising performance in medical imaging for under-sampled and low-dose scenarios. However, it requires large amount of memory and extensive time for the training. It is…
Cellular Electron Cryo-Tomography (CECT) is a powerful imaging technique for the 3D visualization of cellular structure and organization at submolecular resolution. It enables analyzing the native structures of macromolecular complexes and…
Image denoising techniques are essential to reducing noise levels and enhancing diagnosis reliability in low-dose computed tomography (CT). Machine learning based denoising methods have shown great potential in removing the complex and…
Computed tomography (CT) is widely used in screening, diagnosis, and image-guided therapy for both clinical and research purposes. Since CT involves ionizing radiation, an overarching thrust of related technical research is development of…
Optical Coherence Tomography (OCT) is a widely used non-invasive biomedical imaging modality that can rapidly provide volumetric images of samples. Here, we present a deep learning-based image reconstruction framework that can generate…
Computed Tomography (CT) imaging technique is widely used in geological exploration, medical diagnosis and other fields. In practice, however, the resolution of CT image is usually limited by scanning devices and great expense. Super…
Assume you encounter an inverse problem that shall be solved for a large number of data, but no ground-truth data is available. To emulate this encounter, in this study, we assume it is unknown how to solve the imaging problem of Computed…
In recent years, there has been a growing interest in applying convolutional neural networks (CNNs) to low-level vision tasks such as denoising and super-resolution. Due to the coherent nature of the image formation process, optical…
Computed tomography (CT) uses X-ray measurements taken from sensors around the body to generate tomographic images of the human body. Conventional reconstruction algorithms can be used if the X-ray data are adequately sampled and of high…
This study proposes a novel imaging and reconstruction framework for dual-energy cone-beam CT (DECBCT) using only two orthogonal X-ray projections at different energy levels (2V-DECBCT). The goal is to enable fast and low-dose DE volumetric…
SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…
Scatter can account for large errors in cone-beam CT (CBCT) due to its wide field of view, and its complicated nature makes its compensation difficult. Iterative polyenergetic reconstruction algorithms offer the potential to provide…
CT images corrupted by metal artifacts have serious negative effects on clinical diagnosis. Considering the difficulty of collecting paired data with ground truth in clinical settings, unsupervised methods for metal artifact reduction are…
Limited view tomographic reconstruction aims to reconstruct a tomographic image from a limited number of sinogram or projection views arising from sparse view or limited angle acquisitions that reduce radiation dose or shorten scanning…
High dynamic range (HDR) imaging is an indispensable technique in modern photography. Traditional methods focus on HDR reconstruction from multiple images, solving the core problems of image alignment, fusion, and tone mapping, yet having a…
We demonstrate computerized tomography (CT) reconstructions from absorption, phase and dark-field signals obtained from scans acquired when the x-ray probe light is modulated with speckle. Two different interlaced schemes are proposed to…
Computational spectrometers have mobile application potential, such as on-site detection and self-diagnosis, by offering compact size, fast operation time, high resolution, wide working range, and low-cost production. Although these…