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Clustering single-cell RNA sequence (scRNA-seq) data poses statistical and computational challenges due to their high-dimensionality and data-sparsity, also known as `dropout' events. Recently, Regularized Auto-Encoder (RAE) based deep…

Machine Learning · Computer Science 2021-07-19 Arnab Kumar Mondal , Himanshu Asnani , Parag Singla , Prathosh AP

Generative AutoEncoders require a chosen probability distribution in latent space, usually multivariate Gaussian. The original Variational AutoEncoder (VAE) uses randomness in encoder - causing problematic distortion, and overlaps in latent…

Machine Learning · Computer Science 2019-01-15 Jarek Duda

We propose the Wasserstein Auto-Encoder (WAE)---a new algorithm for building a generative model of the data distribution. WAE minimizes a penalized form of the Wasserstein distance between the model distribution and the target distribution,…

Machine Learning · Statistics 2019-12-06 Ilya Tolstikhin , Olivier Bousquet , Sylvain Gelly , Bernhard Schoelkopf

Deep latent variable models, trained using variational autoencoders or generative adversarial networks, are now a key technique for representation learning of continuous structures. However, applying similar methods to discrete structures,…

Machine Learning · Computer Science 2018-07-02 Jake Zhao , Yoon Kim , Kelly Zhang , Alexander M. Rush , Yann LeCun

A new algorithmic framework is proposed for learning autoencoders of data distributions. We minimize the discrepancy between the model and target distributions, with a \emph{relational regularization} on the learnable latent prior. This…

Machine Learning · Computer Science 2020-06-29 Hongteng Xu , Dixin Luo , Ricardo Henao , Svati Shah , Lawrence Carin

Variational Autoencoder (VAE) and its variations are classic generative models by learning a low-dimensional latent representation to satisfy some prior distribution (e.g., Gaussian distribution). Their advantages over GAN are that they can…

Computer Vision and Pattern Recognition · Computer Science 2020-09-24 Cong Geng , Jia Wang , Li Chen , Zhiyong Gao

Regularized autoencoders learn the latent codes, a structure with the regularization under the distribution, which enables them the capability to infer the latent codes given observations and generate new samples given the codes. However,…

Machine Learning · Computer Science 2019-02-18 Wenju Xu , Shawn Keshmiri , Guanghui Wang

Deep generative models are attracting great attention as a new promising approach for molecular design. All models reported so far are based on either variational autoencoder (VAE) or generative adversarial network (GAN). Here we propose a…

Chemical Physics · Physics 2019-12-13 Seung Hwan Hong , Jaechang Lim , Seongok Ryu , Woo Youn Kim

As one of the most popular generative models, Variational Autoencoder (VAE) approximates the posterior of latent variables based on amortized variational inference. However, when the decoder network is sufficiently expressive, VAE may lead…

Machine Learning · Computer Science 2021-10-26 Dazhong Shen , Chuan Qin , Chao Wang , Hengshu Zhu , Enhong Chen , Hui Xiong

The latent space of generative modeling is long dominated by the VAE encoder. The latents from the pretrained representation encoders (e.g., DINO, SigLIP, MAE) are previously considered inappropriate for generative modeling. Recently, RAE…

Artificial Intelligence · Computer Science 2026-04-03 Hu Yu , Hang Xu , Jie Huang , Zeyue Xue , Haoyang Huang , Nan Duan , Feng Zhao

Variational auto-encoders (VAEs) are a powerful approach to unsupervised learning. They enable scalable approximate posterior inference in latent-variable models using variational inference (VI). A VAE posits a variational family…

Machine Learning · Computer Science 2022-06-08 Samarth Sinha , Adji B. Dieng

Unsupervised representation learning via generative modeling is a staple to many computer vision applications in the absence of labeled data. Variational Autoencoders (VAEs) are powerful generative models that learn representations useful…

Machine Learning · Computer Science 2020-03-24 Riddhish Bhalodia , Iain Lee , Shireen Elhabian

Variational Autoencoder (VAE), a simple and effective deep generative model, has led to a number of impressive empirical successes and spawned many advanced variants and theoretical investigations. However, recent studies demonstrate that,…

Machine Learning · Computer Science 2019-01-08 Xuezhe Ma , Chunting Zhou , Eduard Hovy

Deterministic Rank Reduction Autoencoders (RRAEs) enforce by construction a regularization on the latent space by applying a truncated SVD. While this regularization makes Autoencoders more powerful, using them for generative purposes is…

Machine Learning · Computer Science 2025-10-15 Jad Mounayer , Alicia Tierz , Jerome Tomezyk , Chady Ghnatios , Francisco Chinesta

Variational Autoencoders (VAEs) have experienced recent success as data-generating models by using simple architectures that do not require significant fine-tuning of hyperparameters. However, VAEs are known to suffer from…

Machine Learning · Statistics 2020-07-22 Wei Cheng , Gregory Darnell , Sohini Ramachandran , Lorin Crawford

Variational Autoencoders (VAEs) provide a theoretically-backed and popular framework for deep generative models. However, learning a VAE from data poses still unanswered theoretical questions and considerable practical challenges. In this…

Machine Learning · Computer Science 2020-06-01 Partha Ghosh , Mehdi S. M. Sajjadi , Antonio Vergari , Michael Black , Bernhard Schölkopf

The field of neural generative models is dominated by the highly successful Generative Adversarial Networks (GANs) despite their challenges, such as training instability and mode collapse. Auto-Encoders (AE) with regularized latent space…

Computer Vision and Pattern Recognition · Computer Science 2020-05-19 Arnab Kumar Mondal , Sankalan Pal Chowdhury , Aravind Jayendran , Parag Singla , Himanshu Asnani , Prathosh AP

Variational autoencoders (VAEs) are one of the powerful unsupervised learning frameworks in NLP for latent representation learning and latent-directed generation. The classic optimization goal of VAEs is to maximize the Evidence Lower Bound…

Machine Learning · Computer Science 2022-11-02 Jianfei Zhang , Jun Bai , Chenghua Lin , Yanmeng Wang , Wenge Rong

Tokenizers are a crucial component of latent diffusion models, as they define the latent space in which diffusion models operate. However, existing tokenizers are primarily designed to improve reconstruction fidelity or inherit pretrained…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Zhengrong Yue , Taihang Hu , Mengting Chen , Haiyu Zhang , Zihao Pan , Tao Liu , Zikang Wang , Jinsong Lan , Xiaoyong Zhu , Bo Zheng , Yali Wang

The choice of an appropriate bottleneck dimension and the application of effective regularization are both essential for Autoencoders to learn meaningful representations from unlabeled data. In this paper, we introduce a new class of…

Machine Learning · Computer Science 2025-03-26 Jad Mounayer , Sebastian Rodriguez , Chady Ghnatios , Charbel Farhat , Francisco Chinesta
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