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Chemotaxis phenomena govern the directed movement of micro-organisms in response to chemical stimuli. In this paper, we investigate two Keller--Segel systems of reaction-advection-diffusion equations modeling chemotaxis on thin networks.…

Analysis of PDEs · Mathematics 2024-04-02 Hewan Shemtaga , Wenxian Shen , Selim Sukhtaiev

The parabolic-elliptic Keller-Segel equation with sensitivity saturation, because of its pattern formation ability, is a challenge for numerical simulations. We provide two finite-volume schemes whose goals are to preserve, at the discrete…

Numerical Analysis · Mathematics 2018-10-30 Luís Neves de Almeida , Federica Bubba , Benoît Perthame , Camille Pouchol

The Keller-Segel model is a system of partial differential equations that describes the movement of cells or organisms in response to chemical signals, a phenomenon known as chemotaxis. In this study, we analyze a doubly parabolic…

Analysis of PDEs · Mathematics 2025-03-27 Anne Caroline Bronzi , Crystianne Lilian de Andrade

This paper deals with a class of macroscopic models for cell migration in a saturated medium for two-species mixtures. Those species tend to achieve some motion according to a desired velocity, and congestion forces them to adapt their…

Numerical Analysis · Mathematics 2015-03-18 Julien Dambrine , Nicolas Meunier , Bertrand Maury , Aude Roudneff-Chupin

Chemotaxis describes the movement of an organism, such as single or multi-cellular organisms and bacteria, in response to a chemical stimulus. Two widely used models to describe the phenomenon are the celebrated Keller-Segel equation and a…

Analysis of PDEs · Mathematics 2024-01-11 Kathrin Hellmuth , Christian Klingenberg , Qin Li , Min Tang

This paper is concerned with numerical approximation of some two-dimensional Keller-Segel chemotaxis models, especially those generating pattern formations. The numerical resolution of such nonlinear parabolic-parabolic or…

Numerical Analysis · Mathematics 2020-10-29 M. Benzakour Amine

Simulations of biophysical systems inevitably include steps that correspond to time integrations of ordinary differential equations. These equations are often related to enzyme action in the synthesis and destruction of molecular species,…

Biological Physics · Physics 2009-03-31 Roberto Chignola , Alessio Del Fabbro , Edoardo Milotti

We describe a methodology to build vectorial kinetic schemes, targetting the numerical solution of linear symmetric-hyperbolic systems of conservation laws -a minimal application case for those schemes. Precisely, we fully detail the…

Numerical Analysis · Mathematics 2025-12-10 Emmanuel Audusse , Sébastien Boyaval , Virgile Dubos , Minh-Hoang Le

We study the Keller-Segel model of chemotaxis and develop a composite particle-grid numerical method with adaptive time stepping which allows us to accurately resolve singular solutions. The numerical findings (in two dimensions) are then…

Analysis of PDEs · Mathematics 2013-02-20 Ibrahim Fatkullin

The run and tumble process is well established in order to describe the movement of bacteria in response to a chemical stimulus. However the relation between the tumbling rate and the internal state of bacteria is poorly understood. The…

Analysis of PDEs · Mathematics 2021-08-27 Benoit Perthame , Weiran Sun , Min Tang , Shugo Yasuda

The Keller-Segel system describes the collective motion of cells that are attracted by a chemical substance and are able to emit it. In its simplest form, it is a conservative drift-diffusion equation for the cell density coupled to an…

Analysis of PDEs · Mathematics 2010-10-29 Adrien Blanchet , Jean Dolbeault , Miguel Escobedo , Javier Fernández

This paper aims to develop numerical approximations of the Keller--Segel equations that mimic at the discrete level the lower bounds and the energy law of the continuous problem. We solve these equations for two unknowns: the organism (or…

Numerical Analysis · Mathematics 2022-07-25 Santiago Badia , Jesús Bonilla , Juan Vicente Gutiérrez-Santacreu

We develop and analyze numerical methods for a stochastic Keller-Segel system perturbed by Stratonovich noise, which models chemotactic behavior under randomly fluctuating environmental conditions. The proposed fully discrete scheme couples…

Numerical Analysis · Mathematics 2025-07-25 Liet Vo

The Keller-Segel-Navier-Stokes system governs chemotaxis in liquid environments. This system is to be solved for the organism and chemoattractant densities and for the fluid velocity and pressure. It is known that if the total initial cell…

Numerical Analysis · Mathematics 2023-02-02 Jesús Bonilla , Juan Vicente Gutiérrez-Santacreu

We consider a stochastic Keller-Segel-Navier-Stokes system in $R^2$ describing the collective motion of cells in an ambient stochastic fluid flow, where the cells are attracted by a chemical substance and transported by the ambient fluid…

Analysis of PDEs · Mathematics 2026-05-19 Fanze Kong , Chen-Chih Lai , Krutika Tawri

For a Keller-Segel model for chemotaxis in two spatial dimensions we consider a modification of a positivity preserving fully discrete scheme using a local extremum diminishing flux limiter. We discretize space using piecewise linear finite…

Numerical Analysis · Mathematics 2026-02-20 Panagiotis Chatzipantelidis , Christos Pervolianakis

Computer modeling of multicellular systems has been a valuable tool for interpreting and guiding in vitro experiments relevant to embryonic morphogenesis, tumor growth, angiogenesis and, lately, structure formation following the printing of…

Biological Physics · Physics 2015-05-28 Elijah Flenner , Lorant Janosi , Bogdan Barz , Adrian Neagu , Gabor Forgacs , Ioan Kosztin

The flux limited Keller-Segel (FLKS) system is a macroscopic model describing bacteria motion by chemotaxis which takes into account saturation of the velocity. The hyper-bolic form and some special parabolic forms have been derived from…

Analysis of PDEs · Mathematics 2018-01-23 Benoît Perthame , Nicolas Vauchelet , Zhian Wang

We present a discrete model of chemotaxis whereby cells responding to a chemoattractant are seen as individual agents whose movement is described through a set of rules that result in a biased random walk. In order to take into account…

Analysis of PDEs · Mathematics 2020-03-27 Federica Bubba , Tommaso Lorenzi , Fiona R Macfarlane

Chemotaxis systems of Keller--Segel type constitute one of the central mathematical frameworks for understanding aggregation phenomena in biological and ecological systems. Over the past decades, the theory has evolved from the classical…

Analysis of PDEs · Mathematics 2026-03-06 Kolade M Owolabi , Eben Mare , Clara O Ijalana , Kolawole S Adegbie