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Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention…

Quantitative Methods · Quantitative Biology 2025-03-14 Rajiv Krishnakumar , Julien Baglio , Frederik F. Flöther , Christian Ruiz , Stefan Habringer , Nicole H. Romano

Early diagnosis of treatable diseases is essential for improving healthcare, and many diseases' onsets are predictable from annual lab tests and their temporal trends. We introduce a multi-resolution convolutional neural network for early…

Machine Learning · Computer Science 2016-03-14 Narges Razavian , David Sontag

Survival modeling in healthcare relies on explainable statistical models; yet, their underlying assumptions are often simplistic and, thus, unrealistic. Machine learning models can estimate more complex relationships and lead to more…

Quantifying a patient's health status provides clinicians with insight into patient risk, and the ability to better triage and manage resources. Early Warning Scores (EWS) are widely deployed to measure overall health status, and risk of…

Artificial Intelligence · Computer Science 2024-07-15 Thea Barnes , Enrico Werner , Jeffrey N. Clark , Raul Santos-Rodriguez

In recent years, increasingly augmentation of health data, such as patient Electronic Health Records (EHR), are becoming readily available. This provides an unprecedented opportunity for knowledge discovery and data mining algorithms to dig…

Machine Learning · Computer Science 2019-05-09 Xi Sheryl Zhang , Fengyi Tang , Hiroko Dodge , Jiayu Zhou , Fei Wang

In today's world, a massive amount of data is available in almost every sector. This data has become an asset as we can use this enormous amount of data to find information. Mainly health care industry contains many data consisting of…

Machine Learning · Computer Science 2022-03-10 Hafsa Binte Kibria , Abdul Matin

As artificial intelligence systems move toward clinical deployment, ensuring reliable prediction behavior is fundamental for safety-critical decision-making tasks. One proposed safeguard is selective prediction, where models can defer…

Machine Learning · Computer Science 2026-05-25 L. Julián Lechuga López , Farah E. Shamout , Tim G. J. Rudner

Failure detection in automated image classification is a critical safeguard for clinical deployment. Detected failure cases can be referred to human assessment, ensuring patient safety in computer-aided clinical decision making. Despite its…

Artificial Intelligence · Computer Science 2022-10-25 Melanie Bernhardt , Fabio De Sousa Ribeiro , Ben Glocker

Mortality risk is a major concern to patients have just been discharged from the intensive care unit (ICU). Many studies have been directed to construct machine learning models to predict such risk. Although these models are highly…

Applications · Statistics 2021-01-20 Eugene T. Y. Ang , Milashini Nambiar , Yong Sheng Soh , Vincent Y. F. Tan

Machine learning in medicine leverages the wealth of healthcare data to extract knowledge, facilitate clinical decision-making, and ultimately improve care delivery. However, ML models trained on datasets that lack demographic diversity…

Machine Learning · Computer Science 2021-11-19 Songzi Liu , Yuan Luo

Neonatal seizures are a commonly encountered neurological condition. They are the first clinical signs of a serious neurological disorder. Thus, rapid recognition and treatment are necessary to prevent serious fatalities. The use of…

Signal Processing · Electrical Eng. & Systems 2021-12-01 Vishal Nagarajan , Ashwini Muralidharan , Deekshitha Sriraman , Pravin Kumar S

Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

Machine Learning · Computer Science 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

Intensive care unit (ICU) is a crucial hospital department that handles life-threatening cases. Nowadays machine learning (ML) is being leveraged in healthcare ubiquitously. In recent years, management of ICU became one of the most…

Machine Learning · Computer Science 2025-05-26 Alexander Gabitashvili , Philipp Kellmeyer

Objective: When patients develop acute respiratory failure, accurately identifying the underlying etiology is essential for determining the best treatment. However, differentiating between common medical diagnoses can be challenging in…

Machine Learning · Computer Science 2022-04-21 Sarah Jabbour , David Fouhey , Ella Kazerooni , Jenna Wiens , Michael W Sjoding

Computer-aided diagnosis (CAD), a vibrant medical imaging research field, is expanding quickly. Because errors in medical diagnostic systems might lead to seriously misleading medical treatments, major efforts have been made in recent years…

Machine Learning · Computer Science 2023-08-04 Farzaneh Tajidini , Mohammad-Javad Kheiri

Early diagnosis of disease can lead to improved health outcomes, including higher survival rates and lower treatment costs. With the massive amount of information available in electronic health records (EHRs), there is great potential to…

Machine Learning · Computer Science 2022-08-02 Asem Alaa , Erik Mayer , Mauricio Barahona

Early warning of intraoperative adverse events plays a vital role in reducing surgical risk and improving patient safety. While deep learning has shown promise in predicting the single adverse event, several key challenges remain:…

Machine Learning · Computer Science 2026-04-28 Xueyao Wang , Xiuding Cai , Honglin Shang , Yaoyao Zhu , Yu Yao

Background: Extensive clinical evidence suggests that a preventive screening of coronary heart disease (CHD) at an earlier stage can greatly reduce the mortality rate. We use 64 two-dimensional speckle tracking echocardiography (2D-STE)…

Machine Learning · Statistics 2021-05-21 Jingyi Zhang , Huolan Zhu , Yongkai Chen , Chenguang Yang , Huimin Cheng , Yi Li , Wenxuan Zhong , Fang Wang

Viewing the trajectory of a patient as a dynamical system, a recurrent neural network was developed to learn the course of patient encounters in the Pediatric Intensive Care Unit (PICU) of a major tertiary care center. Data extracted from…

Machine Learning · Statistics 2017-01-25 M Aczon , D Ledbetter , L Ho , A Gunny , A Flynn , J Williams , R Wetzel

Multiple organ failure (MOF) is a life-threatening condition. Due to its urgency and high mortality rate, early detection is critical for clinicians to provide appropriate treatment. In this paper, we perform quantitative analysis on early…

Machine Learning · Computer Science 2021-04-26 Yuqing Wang , Yun Zhao , Rachael Callcut , Linda Petzold