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Optimizing the mRNA codon has an essential impact on gene expression for a specific target protein. It is an NP-hard problem; thus, exact solutions to such optimization problems become computationally intractable for realistic problem sizes…

Quantum Physics · Physics 2024-05-13 Hongfeng Zhang , Aritra Sarkar , Koen Bertels

The article presents a study of the Particle Swarm optimization method for scheduling problem. To improve the method's performance a restriction of particles' velocity and an evolutionary meta-optimization were realized. The approach…

Neural and Evolutionary Computing · Computer Science 2020-06-22 Pavel Matrenin , Viktor Sekaev

The thesis deals with Quantum Algorithms for solving Hard Constrained Optimization Problems. It shows how quantum computers can solve difficult everyday problems such as finding the best schedule for social workers or the path of a robot…

Quantum Physics · Physics 2022-03-01 Parfait Atchade-Adelomou

A systematic scheme is proposed to numerically estimate the quantum speed limit and temporal shape of optimal control in two-level and three-level quantum systems with bounded amplitude. For the two-level system, two quantum state…

Quantum Physics · Physics 2023-05-02 Xikun Li

Quantum computing requires the optimization of control pulses to achieve high-fidelity quantum gates. We propose a machine learning-based protocol to address the challenges of evaluating gradients and modeling complex system dynamics. By…

Quantum Physics · Physics 2026-01-27 Paul Surrey , Julian D. Teske , Tobias Hangleiter , Hendrik Bluhm , Pascal Cerfontaine

The rapid progress of physical implementation of quantum computers paved the way for the design of tools to help users write quantum programs for any given quantum device. The physical constraints inherent in current NISQ architectures…

Emerging Technologies · Computer Science 2020-09-08 Chi Zhang , Yanhao Chen , Yuwei Jin , Wonsun Ahn , Youtao Zhang , Eddy Z. Zhang

A quantum computer has now solved a specialized problem believed to be intractable for supercomputers, suggesting that quantum processors may soon outperform supercomputers on scientifically important problems. But flaws in each quantum…

Quantum Physics · Physics 2022-01-21 Timothy Proctor , Kenneth Rudinger , Kevin Young , Erik Nielsen , Robin Blume-Kohout

Due to the sparse connectivity of superconducting quantum computers, qubit communication via SWAP gates accounts for the vast majority of overhead in quantum programs. We introduce a method for improving the speed and reliability of SWAPs…

Quantum Physics · Physics 2021-09-28 Pranav Gokhale , Teague Tomesh , Martin Suchara , Frederic T. Chong

Current quantum programming is dominated by low-level, circuit-centric approaches that limit the potential for compiler optimization. This work presents how a high-level programming construct provides compilers with the semantic information…

Quantum Physics · Physics 2025-10-29 Evandro C. R. Rosa , Jerusa Marchi , Eduardo I. Duzzioni , Rafael de Santiago

We study the factors affecting training time in multi-device deep learning systems. Given a specification of a convolutional neural network, our goal is to minimize the time to train this model on a cluster of commodity CPUs and GPUs. We…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-10-20 Stefan Hadjis , Ce Zhang , Ioannis Mitliagkas , Dan Iter , Christopher Ré

Scaling the size of monolithic quantum computer systems is a difficult task. As the number of qubits within a device increases, a number of factors contribute to decreases in yield and performance. To meet this challenge, distributed…

Developing scalable, fault-tolerant atomic quantum processors requires precise control over large arrays of optical beams. This remains a major challenge due to inherent imperfections in classical control hardware, such as inter-channel…

Quantum Physics · Physics 2026-04-07 Qian Ding , Dirk Englund

Quantum machines are among the most promising technologies expected to provide significant improvements in the following years. However, bridging the gap between real-world applications and their implementation on quantum hardware is still…

We introduce a novel quantum optimization paradigm: the Fixed-Parameter-Count Quantum Approximate Optimization Algorithm (FPC-QAOA). It is a scalable variational framework that maintains a constant number of trainable parameters regardless…

Until high-fidelity quantum computers with a large number of qubits become widely available, classical simulation remains a vital tool for algorithm design, tuning, and validation. We present a simulator for the Quantum Approximate…

Quantum Physics · Physics 2023-11-14 Danylo Lykov , Ruslan Shaydulin , Yue Sun , Yuri Alexeev , Marco Pistoia

We present a method to optimize qubit control parameters during error detection which is compatible with large-scale qubit arrays. We demonstrate our method to optimize single or two-qubit gates in parallel on a nine-qubit system.…

A central aspect for operating future quantum computers is quantum circuit optimization, i.e., the search for efficient realizations of quantum algorithms given the device capabilities. In recent years, powerful approaches have been…

Quantum Physics · Physics 2021-03-16 Thomas Fösel , Murphy Yuezhen Niu , Florian Marquardt , Li Li

Bayesian Optimization is a very effective tool for optimizing expensive black-box functions. Inspired by applications developing and characterizing reaction chemistry using droplet microfluidic reactors, we consider a novel setting where…

Machine Learning · Computer Science 2023-01-12 Jose Pablo Folch , Shiqiang Zhang , Robert M Lee , Behrang Shafei , David Walz , Calvin Tsay , Mark van der Wilk , Ruth Misener

Gate-based quantum computations represent an essential to realize near-term quantum computer architectures. A gate-model quantum neural network (QNN) is a QNN implemented on a gate-model quantum computer, realized via a set of unitaries…

Quantum Physics · Physics 2019-09-04 Laszlo Gyongyosi , Sandor Imre

Quantum variational algorithms have garnered significant interest recently, due to their feasibility of being implemented and tested on noisy intermediate scale quantum (NISQ) devices. We examine the robustness of the quantum approximate…

Quantum Physics · Physics 2019-11-05 Yulong Dong , Xiang Meng , Lin Lin , Robert Kosut , K. Birgitta Whaley
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