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We investigate the properties of membranes under tension by Monte-Carlo simulations of a generic coarse-grained model for lipid bilayers. We give a comprising overview of the behavior of several membrane characteristics, such as the area…

Biological Physics · Physics 2010-03-17 Jörg Neder , Beate West , Peter Nielaba , Friederike Schmid

We propose a minimal model, based on active Brownian particles, for the dynamics of cells confined in a two-state micropattern, composed of two rectangular boxes connected by a bridge, and investigate the transition statistics. A transition…

Soft Condensed Matter · Physics 2022-05-13 F. M. R. Safara , H. P. Melo , M. M. Telo da Gama , N. A. M. Araújo

Using molecular dynamics simulations we study the slow dynamics of a hard sphere fluid confined in a disordered porous matrix. The presence of both discontinuous and continuous glass transitions as well as the complex interplay between…

Soft Condensed Matter · Physics 2009-09-29 Jan Kurzidim , Daniele Coslovich , Gerhard Kahl

We extend a model for the morphology and dynamics of a crawling eukaryotic cell to describe cells on micropatterned substrates. This model couples cell morphology, adhesion, and cytoskeletal flow in response to active stresses induced by…

Cell Behavior · Quantitative Biology 2015-06-17 Brian A. Camley , Yanxiang Zhao , Bo Li , Herbert Levine , Wouter-Jan Rappel

Collective and directed motility or swarming is an emergent phenomenon displayed by many self-organized assemblies of active biological matter such as clusters of embryonic cells during tissue development, cancerous cells during tumor…

Biological Physics · Physics 2016-04-05 Katherine Copenhagen , Ajay Gopinathan

Motivated by recent experiments, we study a system of self-propelled colloids that experience short-range attractive interactions and are confined to a surface. Using simulations we find that the phase behavior for such a system is…

Soft Condensed Matter · Physics 2013-07-30 Gabriel S. Redner , Aparna Baskaran , Michael F. Hagan

We develop a minimal theoretical model that reveals a structured steady-state flux field with four alternating local circulation, a phenomenon we refer to as quadrupolar gyration. A passive Brownian particle is confined to move in a…

Statistical Mechanics · Physics 2025-08-13 Iman Abdoli , Hartmut Löwen

We study a model of contraction-based cell motility inside a microchannel to investigate the regulation of cell polarization and motion by the mechanical resistance of the environment. A positive feedback between the asymmetry of the…

Biological Physics · Physics 2024-02-28 Tapas Singha , Pierre Sens

Cells are modeled with spherical grains connected each other. Each cell can shrink and swell by transporting its fluid content to other connected neighbor while still maintaining its density at constant value. As a spherical part of a cell…

Biological Physics · Physics 2014-02-27 Sparisoma Viridi , Nuning Nuraini

Eukaryotic flagella are active structures with a complex architecture of microtubules, motor proteins and elastic links. They are capable of whiplike motions driven by motors sliding along filaments that are themselves constrained at an…

Soft Condensed Matter · Physics 2012-11-22 Raghunath Chelakkot , Arvind Gopinath , L. Mahadevan , Michael F. Hagan

Self-propelled particles undergoing persistent motion can accumulate either through excluded-volume interactions or through quorum sensing, where self-propulsion decreases at high local density. Using kinetic balance theory and simulations,…

Soft Condensed Matter · Physics 2025-12-03 L. de Souza , E. F. Teixeira , G. M. Viswanathan , P. Sollich , P. de Castro

Many living and artificial systems show a similar emergent behavior and collective motions on different scales, starting from swarms of bacteria to synthetic active particles, herds of mammals and crowds of people. What all these systems…

Soft Condensed Matter · Physics 2024-01-01 Bohdan Senyuk , Jin-Sheng Wua , Ivan I. Smalyukh

Cell spreading and motility on an adhesive substrate are driven by the active physical forces generated by the actin cytoskeleton. We have recently shown that coupling curved membrane complexes to protrusive forces, exerted by the actin…

Soft Condensed Matter · Physics 2023-04-04 Shubhadeep Sadhukhan , Samo Penič , Aleš Iglič , Nir Gov

To model the morphogenesis of rod-shaped bacterial micro-colony, several individual-based models have been proposed in the biophysical literature. When studying the shape of micro-colonies, most models present interaction forces such as…

Cell Behavior · Quantitative Biology 2020-08-12 Marie Doumic , Sophie Hecht , Diane Peurichard

Recent studies aimed at investigating artificial analogs of bacterial colonies have shown that low-density suspensions of self-propelled particles confined in two dimensions can assemble into finite aggregates that merge and split, but have…

Soft Condensed Matter · Physics 2015-06-17 B. M. Mognetti , A. Šarić , S. Angioletti-Uberti , A. Cacciuto , C. Valeriani , D. Frenkel

Many fundamental biological processes are dependent on cellular migration. Although the mechanical mechanisms of single-cell migration are relatively well understood, those underlying migration of multiple cells adhered to each other in a…

Biological Physics · Physics 2023-07-25 Katsuhiko Sato

We set up a mesoscopic theory for interacting Brownian particles embedded in a nonequilibrium environment, starting from the microscopic interacting many-body theory. Using nonequilibrium linear response theory, we characterize the…

Statistical Mechanics · Physics 2017-01-04 Stefano Steffenoni , Klaus Kroy , Gianmaria Falasco

Using Brownian vibrators, where single particles can undergo Brownian motion under vibration, we experimentally investigated self-organized structures and dynamics of quasi-two-dimensional (quasi-2d) granular materials with volume fractions…

Soft Condensed Matter · Physics 2023-01-18 Yangrui Chen , Jie Zhang

At thermal equilibrium, intensive quantities like temperature and pressure have to be uniform throughout the system, restricting inhomogeneous systems composed of different phases. The paradigmatic example is the coexistence of vapor and…

Statistical Mechanics · Physics 2021-01-26 Thomas Speck

We study quasi two-dimensional, monodisperse systems of active Brownian particles (ABPs) for a range of activities, stiffnesses, and densities. We develop a microscopic, analytical method for predicting the dense phase structure formed…

Soft Condensed Matter · Physics 2021-06-24 Nicholas Lauersdorf , Thomas Kolb , Moslem Moradi , Ehssan Nazockdast , Daphne Klotsa