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Cells often migrate on curved surfaces inside the body, such as curved tissues, blood vessels or highly curved protrusions of other cells. Recent \textit{in-vitro} experiments provide clear evidence that motile cells are affected by the…

We examine a minimal model for an active colloidal fluid in the form of self-propelled Brownian hard spheres that interact purely through excluded volume. Despite the absence of an aligning interaction, this system shows the signature…

Soft Condensed Matter · Physics 2017-08-23 Gabriel S. Redner , Michael F. Hagan , Aparna Baskaran

The study of the interactions of living adherent cells with mechanically stable (visco)elastic materials enables understanding and exploiting physiological phenomena mediated by cell-extracellular communication. However, insight on the…

Recent experimental studies have demonstrated that cellular motion can be directed by topographical gradients, such as those resulting from spatial variations in the features of a micropatterned substrate. This phenomenon, known as…

A simple theoretical approach is used to investigate active colloids at the free interface and near repulsive substrates. We employ dynamical density functional theory to determine the steady-state density profiles in an effective…

Soft Condensed Matter · Physics 2017-02-03 René Wittmann , Joseph M. Brader

Within a simple model of attractive active Brownian particles, we predict flocking behavior and challenge the widespread idea that alignment interactions are necessary to observe this collective phenomenon. Here, we show that even…

Soft Condensed Matter · Physics 2023-04-19 Lorenzo Caprini , Hartmut Löwen

An important question in the field of active matter is whether or not it is possible to predict the phase behavior of these systems. Here, we study the phase coexistence of binary mixtures of torque-free active Brownian particles, for both…

Soft Condensed Matter · Physics 2020-04-03 Berend van der Meer , Vasileios Prymidis , Marjolein Dijkstra , Laura Filion

Swarming or collective motion of living entities is one of the most common and spectacular manifestations of living systems having been extensively studied in recent years. A number of general principles have been established. The…

Cell Behavior · Quantitative Biology 2014-06-06 Elod Mehes , Tamas Vicsek

We computationally study suspensions of slow and fast active Brownian particles that have undergone motility induced phase separation and are at steady state. Such mixtures, of varying non-zero activity, remain largely unexplored even…

Soft Condensed Matter · Physics 2024-07-11 Nicholas J Lauersdorf , Ehssan Nazockdast , Daphne Klotsa

We investigate the behavior of colloidal suspensions with different volume fractions confined between parallel walls under a range of steady shears. We model the particles using molecular dynamics (MD) with full hydrodynamic interactions…

Soft Condensed Matter · Physics 2014-09-18 Frances E. Mackay , Kyle Pastor , Mikko Karttunen , Colin Denniston

Confluent cell monolayers and epithelia tissues show remarkable patterns and correlations in structural arrangements and actively-driven collective flows. We simulate these properties using multiphase field models. The models are based on…

Soft Condensed Matter · Physics 2021-12-08 Dennis Wenzel , Axel Voigt

The settling of colloidal particles with short-ranged attractions is investigated via highly resolved immersed boundary simulations. At modest volume fractions, we show that inter-colloid attractions lead to clustering that reduces the…

Soft Condensed Matter · Physics 2018-03-29 Andrew M. Fiore , Gang Wang , James W. Swan

The competition of depletion attractions and longer-ranged repulsions between colloidal particles in colloid-polymer mixtures leads to the formation of heterogeneous gel-like structures. For instance, gel networks, i.e., states where the…

Soft Condensed Matter · Physics 2021-06-24 Matthias Gimperlein , Michael Schmiedeberg

After summarizing basic features of self-organization such as entropy export, feedbacks and nonlinear dynamics, we discuss several examples in biology. The main part of the paper is devoted to a model of active Brownian motion that allows a…

Statistical Mechanics · Physics 2007-05-23 Werner Ebeling , Frank Schweitzer

A microscopic, stochastic, minimal model for collective and cohesive motion of identical self-propelled particles is introduced. Even though the particles interact strictly locally in a very noisy manner, we show that cohesion can be…

Statistical Mechanics · Physics 2010-01-05 Guillaume Gregoire , Hugues Chate , Yuhai Tu

In this work we approach cell migration under a large-scale assumption, so that the system reduces to a particle in motion. Unlike classical particle models, the cell displacement results from its internal activity: the cell velocity is a…

Cell Behavior · Quantitative Biology 2018-08-02 Christèle Etchegaray , Nicolas Meunier

We introduce and theoretically investigate a minimal particle-based model for a new class of active matter where particles exhibit directional, volume-conserving division in confinement while interacting sterically, mimicking cells in early…

Soft Condensed Matter · Physics 2024-10-01 Samantha R. Lish , Lukas Hupe , Ramin Golestanian , Philip Bittihn

We report computer simulation results on the cluster formation of dipolar colloidal particles driven by a rotating external field in a quasi-two-dimensional setup. We focus on the interplay between permanent dipolar and hydrodynamic…

Soft Condensed Matter · Physics 2015-06-12 Sebastian Jäger , Holger Stark , Sabine H. L. Klapp

We present a theory for the steady-state dynamics of a two-dimensional system of spherically symmetric active Brownian particles. The derivation of the theory consists of two steps. First, we integrate out the self-propulsions and obtain a…

Soft Condensed Matter · Physics 2019-05-01 Grzegorz Szamel

We use computer simulations to study the onset of collective motion in systems of interacting active particles. Our model is a swarm of active Brownian particles with internal energy depot and interactions inspired by the dissipative…

Statistical Mechanics · Physics 2013-05-31 Vladimir Lobaskin , Maksym Romenskyy