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We consider random search processes alternating stochastically between diffusion and ballistic motion, in which the distribution function of ballistic motion directions varies from point to point in space. The specific space dependence of…

Subcellular Processes · Quantitative Biology 2016-08-29 Karsten Schwarz , Yannick Schröder , Bin Qu , Markus Hoth , Heiko Rieger

Quantifying how spatial disorder affects the movement of a diffusing particle or agent is fundamental to target search studies. When diffusion occurs on a network, that is on a highly disordered environment, we lack the mathematical tools…

Statistical Mechanics · Physics 2025-08-15 Daniel Marris , Chittaranjan Hens , Subrata Ghosh , Luca Giuggioli

In many physical situations, there appears the problem of reaching a single target that is spatially distributed. Here we analyse how stochastic resetting, also spatially distributed, can be used to improve the search process when the…

Statistical Mechanics · Physics 2023-11-22 Gregorio García-Valladares , Carlos A. Plata , Antonio Prados , Alessandro Manacorda

Despite having been studied for decades, first passage processes remain an active area of research. In this contribution we examine a particle diffusing in an annulus with an inner absorbing boundary and an outer reflective boundary. We…

Statistical Mechanics · Physics 2022-10-05 Charles Antoine , Julian Talbot

Efficient search acts as a strong selective force in biological systems ranging from cellular populations to predator-prey systems. The search processes commonly involve finding a stationary or mobile target within a heterogeneously…

Biological Physics · Physics 2018-01-03 Youness Azimzade , Alireza Mashaghi

For more than a century lattice random walks have been employed ubiquitously, both as a theoretical laboratory to develop intuition about more complex stochastic processes and as a tool to interpret a vast array of empirical observations.…

Statistical Mechanics · Physics 2024-12-31 Luca Giuggioli , Seeralan Sarvaharman , Debraj Das , Daniel Marris , Toby Kay

Random search for one or more targets in a bounded domain occurs widely in nature, with examples ranging from animal foraging to the transport of vesicles within cells. Most theoretical studies take a searcher-centric viewpoint, focusing on…

Statistical Mechanics · Physics 2021-01-13 Paul C Bressloff

In olfactory search an immobile target emits chemical molecules at constant rate. The molecules are transported by the medium which is assumed to be turbulent. Considering a searcher able to detect such chemical signals and whose motion…

Statistical Mechanics · Physics 2014-02-12 Juan Duque-Rodríguez , David Gómez-Ullate , Carlos Mejía-Monasterio

The presence of temporal correlations in random movement trajectories is a widespread phenomenon across biological, chemical and physical systems. The ubiquity of persistent and anti-persistent motion in many natural and synthetic systems…

Statistical Mechanics · Physics 2024-07-03 Daniel Marris , Luca Giuggioli

In this paper a lattice model for diffusional transport of particles in the interphase cell nucleus is proposed. Dense networks of chromatin fibers are created by three different methods: randomly distributed, non-interconnected obstacles,…

Biological Physics · Physics 2009-11-13 Annika Wedemeier , Holger Merlitz , Chen-Xu Wu , Jörg Langowski

The diffusive transport of particles in anisotropic media is a fundamental phenomenon in computational, medical and biological disciplines. While deterministic models (partial differential equations) of such processes are well established,…

Computational Physics · Physics 2025-10-20 Luke P. Filippini , Adrianne L. Jenner , Elliot J. Carr

The standard setup for single-file diffusion is diffusing particles in one dimension which cannot overtake each other, where the dynamics of a tracer (tagged) particle is of main interest. In this article we generalise this system and…

Statistical Mechanics · Physics 2015-06-18 Robin Forsling , Lloyd Sanders , Tobias Ambjörnsson , Ludvig Lizana

As a first step in the first passage problem for passive tracer in stratified porous media, we consider the case of a two-dimensional system consisting of two layers with different convection velocities. Using a lattice generating function…

Condensed Matter · Physics 2009-10-22 Jysoo Lee , Joel Koplik

We summarise different results on the diffusion of a tracer particle in lattice gases of hard-core particles with stochastic dynamics, which are confined to narrow channels -- single-files, comb-like structures and quasi-one-dimensional…

Statistical Mechanics · Physics 2018-11-14 O. Benichou , P. Illien , G. Oshanin , A. Sarracino , R. Voituriez

The first passage search of a diffusing target (prey) by multiple searchers (predators) in confinement is an important problem in the stochastic process literature. While the analogous problem in open space has been studied in some details,…

Statistical Mechanics · Physics 2021-01-04 Indrani Nayak , Amitabha Nandi , Dibyendu Das

A two-dimensional lattice model for the formation and evolution of shear bands in granular media is proposed. Each lattice site is assigned a random variable which reflects the local density. At every time step, the strain is localized…

Statistical Mechanics · Physics 2013-05-29 Janos Torok , Supriya Krishnamurthy , Janos Kertesz , Stephane Roux

The transport of particles in cells is influenced by the properties of intracellular networks they traverse while searching for localized target regions or reaction partners. Moreover, given the rapid turnover in many intracellular…

Biological Physics · Physics 2024-06-21 Lachlan Elam , Mónica C. Quiñones-Frías , Ying Zhang , Avital A. Rodal , Thomas G. Fai

We present a novel framework for understanding node target search in systems organized as hierarchical networks-within-networks. Our work generalizes traditional search models on complex networks, where the mean-first passage time is…

Biological Physics · Physics 2024-11-06 Lucas Hedström , Seong-Gyu Yang , Ludvig Lizana

Transport of nanoscale objects in complex, structured environments plays a key role in a wide range of processes, from biomolecular dynamics in extracellular spaces to transport in porous materials such as filters and catalysts. While…

We study a model for a protein searching for a target, using facilitated diffusion, on a DNA molecule confined in a finite volume. The model includes three distinct pathways for facilitated diffusion: (a) sliding - in which the protein…

Subcellular Processes · Quantitative Biology 2009-01-28 Michael Sheinman , Yariv Kafri
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