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Flux balance analysis has proven an effective tool for analyzing metabolic networks. In flux balance analysis, reaction rates and optimal pathways are ascertained by solving a linear program, in which the growth rate is maximized subject to…

Optimization and Control · Mathematics 2018-04-10 Amir Akbari , Paul I. Barton

Causal effect estimation from observational data is one of the essential problems in causal inference. However, most estimation methods rely on the strong assumption that all confounders are observed, which is impractical and untestable in…

Methodology · Statistics 2023-02-14 Yubai Yuan , Annie Qu

How social networks influence human behavior has been an interesting topic in applied research. Existing methods often utilized scale-level behavioral data to estimate the influence of a social network on human behavior. This study proposes…

Social and Information Networks · Computer Science 2025-01-08 Jina Park , Ick Hoon Jin , Minjeong Jeon

The joint analysis of biomedical data in Alzheimer's Disease (AD) is important for better clinical diagnosis and to understand the relationship between biomarkers. However, jointly accounting for heterogeneous measures poses important…

Methodology · Statistics 2018-08-14 Luigi Antelmi , Nicholas Ayache , Philippe Robert , Marco Lorenzi

Latent variable models are used to estimate variables of interest quantities which are observable only up to some measurement error. In many studies, such variables are known but not precisely quantifiable (such as "job satisfaction" in…

Machine Learning · Statistics 2012-10-19 Ricardo Silva

Multiple indications of disease progression found in a cancer patient by loco-regional relapse, distant metastasis and death. Early identification of these indications is necessary to change the treatment strategy. Biomarkers play an…

Applications · Statistics 2021-07-23 Atanu Bhattacharjee , Gajendra K. Vishwakarma , Souvik Banerjee

Sparse latent multi-factor models have been used in many exploratory and predictive problems with high-dimensional multivariate observations. Because of concerns with identifiability, the latent factors are almost always assumed to be…

Applications · Statistics 2013-12-09 Vinicius Diniz Mayrink , Joseph Edward Lucas

It is of scientific interest to identify essential biomarkers in biological processes underlying diseases to facilitate precision medicine. Factor analysis (FA) has long been used to address this goal: by assuming latent biological pathways…

Methodology · Statistics 2026-03-18 Jiachen Cai , Robert J. B. Goudie , Brian D. M. Tom

Bayesian change-point detection, together with latent variable models, allows to perform segmentation over high-dimensional time-series. We assume that change-points lie on a lower-dimensional manifold where we aim to infer subsets of…

Machine Learning · Statistics 2020-11-04 Lorena Romero-Medrano , Pablo Moreno-Muñoz , Antonio Artés-Rodríguez

Multivariate categorical data occur in many applications of machine learning. One of the main difficulties with these vectors of categorical variables is sparsity. The number of possible observations grows exponentially with vector length,…

Machine Learning · Statistics 2015-03-10 Yarin Gal , Yutian Chen , Zoubin Ghahramani

A plethora of networks is being collected in a growing number of fields, including disease transmission, international relations, social interactions, and others. As data streams continue to grow, the complexity associated with these highly…

Machine Learning · Statistics 2018-09-11 Daniele Durante , Nabanita Mukherjee , Rebecca C. Steorts

In the analysis of observational data in social sciences and businesses, it is difficult to obtain a "(quasi) single-source dataset" in which the variables of interest are simultaneously observed. Instead, multiple-source datasets are…

Methodology · Statistics 2021-09-02 Masaki Mitsuhiro , Takahiro Hoshino

Accurate food intake monitoring is crucial for maintaining a healthy diet and preventing nutrition-related diseases. With the diverse range of foods consumed across various cultures, classic food classification models have limitations due…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Hassan Kazemi Tehrani , Jun Cai , Abbas Yekanlou , Sylvia Santosa

Electronic health records (EHRs) are increasingly used for clinical and comparative effectiveness research, but suffer from missing data. Motivated by health services research on diabetes care, we seek to increase the quality of EHRs by…

Methodology · Statistics 2020-07-14 Yajuan Si , Mari Palta , Maureen Smith

The prevalence of chronic non-communicable diseases such as obesity has noticeably increased in the last decade. The study of these diseases in early life is of paramount importance in determining their course in adult life and in…

Regular nutrient intake monitoring in hospitalised patients plays a critical role in reducing the risk of disease-related malnutrition (DRM). Although several methods to estimate nutrient intake have been developed, there is still a clear…

Computer Vision and Pattern Recognition · Computer Science 2019-06-13 Ya Lu , Thomai Stathopoulou , Maria F. Vasiloglou , Stergios Christodoulidis , Beat Blum , Thomas Walser , Vinzenz Meier , Zeno Stanga , Stavroula G. Mougiakakou

Foundation models have achieved remarkable success across various domains, yet their adoption in healthcare remains limited. While significant advances have been made in medical imaging, genetic biomarkers, and time series from electronic…

Current research in food analysis primarily concentrates on tasks such as food recognition, recipe retrieval and nutrition estimation from a single image. Nevertheless, there is a significant gap in exploring the impact of food intake on…

Multimedia · Computer Science 2024-09-26 Yinxuan Gui , Bin Zhu , Jingjing Chen , Chong-Wah Ngo , Yu-Gang Jiang

Datasets may contain observations with multiple labels. If the labels are not mutually exclusive, and if the labels vary greatly in frequency, obtaining a sample that includes sufficient observations with scarcer labels to make inferences…

Machine Learning · Computer Science 2026-05-27 Simon Chung , Colby J. Vorland , Donna L. Maney , Andrew W. Brown

The increased worldwide prevalence of obesity has sparked the interest of the scientific community towards tools that objectively and automatically monitor eating behavior. Despite the study of obesity being in the spotlight, such tools can…

Signal Processing · Electrical Eng. & Systems 2020-10-15 Konstantinos Kyritsis , Christos Diou , Anastasios Delopoulos