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Deep learning-based image generation has seen significant advancements with diffusion models, notably improving the quality of generated images. Despite these developments, generating images with unseen characteristics beneficial for…

Recent work (Bengio et al., 2013) has shown howDenoising Auto-Encoders(DAE) become gener-ative models as a density estimator. However,in practice, the framework suffers from a mixingproblem in the MCMC sampling process and nodirect method…

Machine Learning · Computer Science 2017-01-31 Dong-Hyun Lee

Convolutional neural networks (CNNs) have shown outstanding performance on image denoising with the help of large-scale datasets. Earlier methods naively trained a single CNN with many pairs of clean-noisy images. However, the conditional…

Image and Video Processing · Electrical Eng. & Systems 2021-04-05 Jae Woong Soh , Nam Ik Cho

Collecting annotations from multiple independent sources could mitigate the impact of potential noises and biases from a single source, which is a common practice in medical image segmentation. Learning segmentation networks from…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Yifeng Wang , Luyang Luo , Mingxiang Wu , Qiong Wang , Hao Chen

Learning a medical image segmentation model is an inherently ambiguous task, as uncertainties exist in both images (noise) and manual annotations (human errors and bias) used for model training. To build a trustworthy image segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Xinyu Bai , Wenjia Bai

Generative modelling of entire CT volumes conditioned on clinical reports has the potential to accelerate research through data augmentation, privacy-preserving synthesis and reducing regulator-constraints on patient data while preserving…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Jiayi Wang , Hadrien Reynaud , Franciskus Xaverius Erick , Bernhard Kainz

Flow matching has become a leading framework for generative modeling, but quantifying the uncertainty of its samples remains an open problem. Existing approaches retrain the model with auxiliary variance heads, maintain costly ensembles, or…

Machine Learning · Computer Science 2026-05-22 Jiarui Xing , Song Wang , Jian Wang

Data heterogeneity hinders clinical deployment of medical image analysis models, and generative data augmentation helps mitigate this issue. However, recent diffusion-based methods that synthesize image-mask pairs often ignore distribution…

Image and Video Processing · Electrical Eng. & Systems 2026-04-06 Jie Yang , Ziqi Ye , Aihua Ke , Jian Luo , Bo Cai , Xiaosong Wang

The integrative analysis of histopathological images and genomic data has received increasing attention for survival prediction of human cancers. However, the existing studies always hold the assumption that full modalities are available.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Junjie Zhou , Jiao Tang , Yingli Zuo , Peng Wan , Daoqiang Zhang , Wei Shao

Predicting molecular conformations (or 3D structures) from molecular graphs is a fundamental problem in many applications. Most existing approaches are usually divided into two steps by first predicting the distances between atoms and then…

Machine Learning · Computer Science 2025-01-07 Minkai Xu , Wujie Wang , Shitong Luo , Chence Shi , Yoshua Bengio , Rafael Gomez-Bombarelli , Jian Tang

Learning meaningful latent representations from nonlinear fMRI data remains a fundamental challenge in neuroimaging analysis. Traditional independent component analysis, widely used due to its ability to estimate interpretable functional…

Machine Learning · Computer Science 2026-05-19 Qiang Li , Shujian Yu , Jesus Malo , Jingyu Liu , Tülay Adali , Vince D. Calhoun

Most deep learning models for computational imaging regress a single reconstructed image. In practice, however, ill-posedness, nonlinearity, model mismatch, and noise often conspire to make such point estimates misleading or insufficient.…

Variational autoencoders (VAEs), that are built upon deep neural networks have emerged as popular generative models in computer vision. Most of the work towards improving variational autoencoders has focused mainly on making the…

Machine Learning · Statistics 2016-11-17 Siddharth Agrawal , Ambedkar Dukkipati

Inverse problems aim to determine model parameters of a mathematical problem from given observational data. Neural networks can provide an efficient tool to solve these problems. In the context of Bayesian inverse problems, Uncertainty…

Numerical Analysis · Mathematics 2025-09-16 Andrea Tonini , Tan Bui-Thanh , Francesco Regazzoni , Luca Dede' , Alfio Quarteroni

Accurate image registration is essential in many medical imaging applications, yet most deep registration networks provide little indication of when or where their predictions are unreliable. Existing uncertainty estimation approaches, such…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lin Tian , Xiaoling Hu , Juan Eugenio Iglesias

Synthetic medical image generation has a huge potential for improving healthcare through many applications, from data augmentation for training machine learning systems to preserving patient privacy. Conditional Adversarial Generative…

Image and Video Processing · Electrical Eng. & Systems 2022-05-05 Mohammad Havaei , Ximeng Mao , Yiping Wang , Qicheng Lao

Automatic tumor segmentation is a crucial step in medical image analysis for computer-aided diagnosis. Although the existing methods based on convolutional neural networks (CNNs) have achieved the state-of-the-art performance, many…

Image and Video Processing · Electrical Eng. & Systems 2020-05-11 Shuchao Pang , Anan Du , Mehmet A. Orgun , Yan Wang , Quanzheng Sheng , Shoujin Wang , Xiaoshui Huang , Zhemei Yu

This work presents DCFlow, a novel unsupervised cross-modal flow estimation framework that integrates a decoupled optimization strategy and a cross-modal consistency constraint. Unlike previous approaches that implicitly learn flow…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Runmin Zhang , Jialiang Wang , Si-Yuan Cao , Zhu Yu , Junchen Yu , Guangyi Zhang , Hui-Liang Shen

Different CT segmentation datasets are typically obtained from different scanners under different capture settings and often provide segmentation labels for a limited and often disjoint set of organs. Using these heterogeneous data…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Asim Ukaye , Numan Saeed , Karthik Nandakumar

We propose a novel approach to generate samples from the conditional distribution of patient-specific cardiovascular models given a clinically aquired image volume. A convolutional neural network architecture with dropout layers is first…

Quantitative Methods · Quantitative Biology 2021-09-01 Gabriel Maher , Casey Fleeter , Daniele Schiavazzi , Alison Marsden
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