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Dopamine levels are linked to neurological illnesses like Parkinson's and Alzheimer's. Thus, reliable and sensitive detection of dopamine is crucial for early diagnosis and surveillance of neurodegenerative diseases. Non-noble-metal-based…
This study introduces a hybrid approach integrating advanced plasmonic nanomaterials and machine learning (ML) for high-precision biomolecule detection. We leverage aluminum concave nanocubes (AlCNCs) as an innovative plasmonic substrate to…
Tracing physiological neurotransmitters such as dopamine (DA) with detection limits down to $\mathrm{1\times10^{-8}}$ mM is a critical goal in neuroscience for studying brain functions and progressing the understanding of cerebral disease.…
Stress is one of the main issues of nowadays lifestyle. If it becomes chronic it can have adverse effects on the human body. Thus, the early detection of stress is crucial to prevent its hurting effects on the human body and have a…
Pharmacological challenge imaging has mapped, but rarely quantified, the sensitivity of a biological system to a given drug. We describe a novel method called rapid quantitative pharmacodynamic imaging. This method combines…
Virtual Diagnostic (VD) is a computational tool based on deep learning that can be used to predict a diagnostic output. VDs are especially useful in systems where measuring the output is invasive, limited, costly or runs the risk of…
In the field of pharmacokinetics and pharmacodynamics (PKPD) modeling, which plays a pivotal role in the drug development process, traditional models frequently encounter difficulties in fully encapsulating the complexities of drug…
Parkinson's Disease (PD) is characterized by disorders in motor function such as freezing of gait, rest tremor, rigidity, and slowed and hyposcaled movements. Medication with dopaminergic medication may alleviate those motor symptoms,…
The scope of this research is the identification of unknown piecewise constant parameters of linear regression equation under the finite excitation condition. Compared to the known methods, to make the computational burden lower, only one…
As an important part of linear perspective, vanishing points (VPs) provide useful clues for mapping objects from 2D photos to 3D space. Existing methods are mainly focused on extracting structural features such as lines or contours and then…
This paper investigates different methods and various neural network architectures applicable in the time series classification domain. The data is obtained from a fleet of gas sensors that measure and track quantities such as oxygen and…
Facial expressions play a significant role in human communication and behavior. Psychologists have long studied the relationship between facial expressions and emotions. Paul Ekman et al., devised the Facial Action Coding System (FACS) to…
A Deep Neural Network is applied to classify physical signatures obtained from physical sensor measurements of running gasoline and diesel-powered vehicles and other devices. The classification provides information on the target identities…
Cooperation between temporal convolutional networks (TCN) and graph convolutional networks (GCN) as a processing module has shown promising results in skeleton-based video anomaly detection (SVAD). However, to maintain a lightweight model…
Extracting relevant properties of empirical signals generated by nonlinear, stochastic, and high-dimensional systems is a challenge of complex systems research. Open questions are how to differentiate chaotic signals from stochastic ones,…
This paper applies the classical prediction error method (PEM) to the estimation of nonlinear discrete-time models of neuronal systems subject to input-additive noise. While the nonlinear system exhibits excitability, bifurcations, and…
Functional ultrasound imaging (fUSI) is a cutting-edge technology that measures changes in cerebral blood volume (CBV) by detecting backscattered echoes from red blood cells moving within its field of view (FOV). It offers high…
The existing action recognition methods are mainly based on clip-level classifiers such as two-stream CNNs or 3D CNNs, which are trained from the randomly selected clips and applied to densely sampled clips during testing. However, this…
ANOVA Simultaneous Component Analysis (ASCA) is the current state-of-theart chemometric tool for analyzing and interpreting high-dimensional experimental data from a Design of Experiment (DoE). Being a multivariate extension of the ANOVA,…
Progress in real-time, simultaneous in vivo detection of multiple neurotransmitters will help accelerate advances in neuroscience research. The need for development of probes capable of stable electrochemical detection of rapid…