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The SARS-CoV-2 virus and COVID-19 disease have posed unprecedented and overwhelming demand, challenges and opportunities to domain, model and data driven modeling. This paper provides a comprehensive review of the challenges, tasks,…

Computers and Society · Computer Science 2021-08-05 Longbing Cao , Qing Liu

The novel Wuhan coronavirus known as SARS-CoV-2 has brought almost unprecedented effects for a non-wartime setting, hitting social, economic and health systems hard.~ Being able to bring to bear pharmaceutical interventions to counteract…

Biomolecules · Quantitative Biology 2020-05-15 Edward O. Pyzer-Knapp

Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus. The disease presents with symptoms such as shortness of breath, fever, dry cough, and chronic fatigue, amongst others. Sometimes the symptoms…

Image and Video Processing · Electrical Eng. & Systems 2021-06-25 Shahabedin Nabavi , Azar Ejmalian , Mohsen Ebrahimi Moghaddam , Ahmad Ali Abin , Alejandro F. Frangi , Mohammad Mohammadi , Hamidreza Saligheh Rad

Coronavirus Disease 2019 (COVID-19) has been creating a worldwide pandemic situation. Repurposing drugs, already shown to be free of harmful side effects, for the treatment of COVID-19 patients is an important option in launching novel…

Molecular Networks · Quantitative Biology 2020-07-07 Sumanta Ray , Snehalika Lall , Anirban Mukhopadhyay , Sanghamitra Bandyopadhyay , Alexander Schönhuth

This paper presents a federated learning (FL) approach to train an AI model for SARS-Cov-2 variant classification. We analyze the SARS-CoV-2 spike sequences in a distributed way, without data sharing, to detect different variants of this…

Machine Learning · Computer Science 2023-11-10 Prakash Chourasia , Taslim Murad , Zahra Tayebi , Sarwan Ali , Imdad Ullah Khan , Murray Patterson

Amid the pandemic of 2019 novel coronavirus disease (COVID-19) infected by SARS-CoV-2, a vast amount of drug research for prevention and treatment has been quickly conducted, but these efforts have been unsuccessful thus far. Our objective…

Quantitative Methods · Quantitative Biology 2022-02-03 Kanglin Hsieh , Yinyin Wang , Luyao Chen , Zhongming Zhao , Sean Savitz , Xiaoqian Jiang , Jing Tang , Yejin Kim

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has emphasized the importance and challenges of correctly interpreting antibody test results. Identification of positive and negative samples requires a…

Quantitative Methods · Quantitative Biology 2023-04-26 Rayanne A. Luke , Anthony J. Kearsley , Nora Pisanic , Yukari C. Manabe , David L. Thomas , Christopher D. Heaney , Paul N. Patrone

COVID-19 is an infection caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus 2), which has caused a global outbreak. Current research efforts are focused on the understanding of the molecular mechanisms involved in…

Pattern detection and string matching are fundamental problems in computer science and the accelerated expansion of bioinformatics and computational biology have made them a core topic for both disciplines. The SARS-CoV-2 pandemic has made…

Genomics · Quantitative Biology 2025-05-14 Konstantinos Xylogiannopoulos

The beginning of 2020 has seen the emergence of coronavirus outbreak caused by a novel virus called SARS-CoV-2. The sudden explosion and uncontrolled worldwide spread of COVID-19 show the limitations of existing healthcare systems in timely…

Cryptography and Security · Computer Science 2021-06-29 Dinh C. Nguyen , Ming Ding , Pubudu N. Pathirana , Aruna Seneviratne

Early detection and characterization of coronavirus disease (COVID-19), caused by SARS-CoV-2, remain critical for effective clinical response and public-health planning. The global availability of large-scale viral sequence data presents…

Machine Learning · Computer Science 2025-12-12 Sarwan Ali , Taslim Murad

The world has faced the devastating outbreak of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), or COVID-19, in 2020. Research in the subject matter was fast-tracked to such a point that scientists were struggling to keep up…

Information Retrieval · Computer Science 2020-09-03 Maksim Ekin Eren , Nick Solovyev , Edward Raff , Charles Nicholas , Ben Johnson

The outbreak of novel coronavirus disease (COVID- 19) has claimed millions of lives and has affected all aspects of human life. This paper focuses on the application of deep learning (DL) models to medical imaging and drug discovery for…

Image and Video Processing · Electrical Eng. & Systems 2021-07-21 Subrato Bharati , Prajoy Podder , M. Rubaiyat Hossain Mondal , V. B. Surya Prasath

We demonstrate use of iteratively pruned deep learning model ensembles for detecting pulmonary manifestation of COVID-19 with chest X-rays. This disease is caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)…

Image and Video Processing · Electrical Eng. & Systems 2021-03-08 Sivaramakrishnan Rajaraman , Jen Siegelman , Philip O. Alderson , Lucas S. Folio , Les R. Folio , Sameer K. Antani

The new coronavirus has caused more than one million deaths and continues to spread rapidly. This virus targets the lungs, causing respiratory distress which can be mild or severe. The X-ray or computed tomography (CT) images of lungs can…

Heart disease is one of the significant challenges in today's world and one of the leading causes of many deaths worldwide. Recent advancement of machine learning (ML) application demonstrates that using electrocardiogram (ECG) and patient…

Machine Learning · Computer Science 2021-12-14 Md Manjurul Ahsan , Zahed Siddique

In December 2019, a novel virus called COVID-19 had caused an enormous number of causalities to date. The battle with the novel Coronavirus is baffling and horrifying after the Spanish Flu 2019. While the front-line doctors and medical…

Machine Learning · Computer Science 2023-03-30 MD Abdullah Al Nasim , Aditi Dhali , Faria Afrin , Noshin Tasnim Zaman , Nazmul Karimm , Md Mahim Anjum Haque

Recently, the lung infection due to Coronavirus Disease (COVID-19) affected a large human group worldwide and the assessment of the infection rate in the lung is essential for treatment planning. This research aims to propose a…

Image and Video Processing · Electrical Eng. & Systems 2020-04-29 Seifedine Kadry , Venkatesan Rajinikanth , Seungmin Rho , Nadaradjane Sri Madhava Raja , Vaddi Seshagiri Rao , Krishnan Palani Thanaraj

Given the severity of the SARS-CoV-2 pandemic, a major challenge is to rapidly repurpose existing approved drugs for clinical interventions. While a number of data-driven and experimental approaches have been suggested in the context of…

Computational drug design based on artificial intelligence is an emerging research area. At the time of writing this paper, the world suffers from an outbreak of the coronavirus SARS-CoV-2. A promising way to stop the virus replication is…

Neural and Evolutionary Computing · Computer Science 2020-09-11 Tim Cofala , Lars Elend , Philip Mirbach , Jonas Prellberg , Thomas Teusch , Oliver Kramer
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