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The emergence of generative AI and controllable diffusion has made image-to-image synthesis increasingly practical and efficient. However, when input images exhibit low entropy and sparse, the inherent characteristics of diffusion models…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Hao Wang , Xiwen Chen , Ashish Bastola , Jiayou Qin , Abolfazl Razi

We propose FlowReg, a deep learning-based framework for unsupervised image registration for neuroimaging applications. The system is composed of two architectures that are trained sequentially: FlowReg-A which affinely corrects for gross…

Computer Vision and Pattern Recognition · Computer Science 2021-09-02 Sergiu Mocanu , Alan R. Moody , April Khademi

Shape modelling describes methods aimed at capturing the natural variability of shapes and commonly relies on probabilistic interpretations of dimensionality reduction techniques such as principal component analysis. Due to their…

Computer Vision and Pattern Recognition · Computer Science 2018-10-10 Yaël Balbastre , Mikael Brudfors , Kevin Bronik , John Ashburner

Medical image registration is crucial for various clinical and research applications including disease diagnosis or treatment planning which require alignment of images from different modalities, time points, or subjects. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Ahsan Raza Siyal , Markus Haltmeier , Ruth Steiger , Malik Galijasevic , Elke Ruth Gizewski , Astrid Ellen Grams

Photoacoustic tomography (PAT) offers optical contrast, whereas magnetic resonance imaging (MRI) excels in imaging soft tissue and organ anatomy. The fusion of PAT with MRI holds promising application prospects due to their complementary…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Yutian Zhong , Jinchuan He , Zhichao Liang , Shuangyang Zhang , Qianjin Feng , Lijun Lu , Li Qi

Estimating probabilistic deformable template models is a new approach in the fields of computer vision and probabilistic atlases in computational anatomy. A first coherent statistical framework modelling the variability as a hidden random…

Computation · Statistics 2009-01-16 Stéphanie Allassonnière , Estelle Kuhn

Effective learning of asymmetric and local features in images and other data observed on multi-dimensional grids is a challenging objective critical for a wide range of image processing applications involving biomedical and natural images.…

Methodology · Statistics 2022-10-06 Meng Li , Li Ma

Image registration is fundamental in medical imaging applications, such as disease progression analysis or radiation therapy planning. The primary objective of image registration is to precisely capture the deformation between two or more…

Image and Video Processing · Electrical Eng. & Systems 2024-12-23 Anna Reithmeir , Veronika Spieker , Vasiliki Sideri-Lampretsa , Daniel Rueckert , Julia A. Schnabel , Veronika A. Zimmer

Deformable registration is ubiquitous in medical image analysis. Many deformable registration methods minimize sum of squared difference (SSD) as the registration cost with respect to deformable model parameters. In this work, we construct…

Computer Vision and Pattern Recognition · Computer Science 2016-11-29 Sayan Ghosal , Nilanjan Ray

Diffusion models have recently emerged as powerful generative models in medical imaging. However, it remains a major challenge to combine these data-driven models with domain knowledge to guide brain imaging problems. In neuroimaging,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Ana Lawry Aguila , Dina Zemlyanker , You Cheng , Sudeshna Das , Daniel C. Alexander , Oula Puonti , Annabel Sorby-Adams , W. Taylor Kimberly , Juan Eugenio Iglesias

Statistical shape modeling (SSM) characterizes anatomical variations in a population of shapes generated from medical images. SSM requires consistent shape representation across samples in shape cohort. Establishing this representation…

Computer Vision and Pattern Recognition · Computer Science 2022-03-17 Riddhish Bhalodia , Shireen Elhabian , Jadie Adams , Wenzheng Tao , Ladislav Kavan , Ross Whitaker

Statistical shape modeling (SSM) is an essential tool for analyzing variations in anatomical morphology. In a typical SSM pipeline, 3D anatomical images, gone through segmentation and rigid registration, are represented using…

Computer Vision and Pattern Recognition · Computer Science 2024-01-02 Hong Xu , Shireen Y. Elhabian

A novel approach to perform unsupervised sequential learning for functional data is proposed. Our goal is to extract reference shapes (referred to as templates) from noisy, deformed and censored realizations of curves and images. Our model…

Methodology · Statistics 2016-04-05 Florian Maire , Eric Moulines , Sidonie Lefebvre

We present a postprocessing layer for deformable image registration to make a registration field more diffeomorphic by encouraging Jacobians of the transformation to be positive. Diffeomorphic image registration is important for medical…

Image and Video Processing · Electrical Eng. & Systems 2022-02-03 Soumyadeep Pal , Matthew Tennant , Nilanjan Ray

We develop a new Bayesian model for non-rigid registration of three-dimensional medical images, with a focus on uncertainty quantification. Probabilistic registration of large images with calibrated uncertainty estimates is difficult for…

Computer Vision and Pattern Recognition · Computer Science 2021-10-27 Daniel Grzech , Mohammad Farid Azampour , Huaqi Qiu , Ben Glocker , Bernhard Kainz , Loïc Le Folgoc

The problem of the definition and the estimation of generative models based on deformable templates from raw data is of particular importance for modelling non aligned data affected by various types of geometrical variability. This is…

Computation · Statistics 2009-01-16 Stéphanie Allassonnière , Estelle Kuhn , Alain Trouvé

Neuroimage analysis usually involves learning thousands or even millions of variables using only a limited number of samples. In this regard, sparse models, e.g. the lasso, are applied to select the optimal features and achieve high…

Machine Learning · Computer Science 2015-03-26 Bo Xin , Lingjing Hu , Yizhou Wang , Wen Gao

Computational imaging is crucial in many disciplines from autonomous driving to life sciences. However, traditional model-driven and iterative methods consume large computational power and lack scalability for imaging. Deep learning (DL) is…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Weiru Fan , Xiaobin Tang , Yiyi Liao , Da-Wei Wang

Diffusion magnetic resonance imaging is a noninvasive imaging technique that can indirectly infer the microstructure of tissues and provide metrics which are subject to normal variability across subjects. Potentially abnormal values or…

Image and Video Processing · Electrical Eng. & Systems 2020-08-28 Samuel St-Jean , Max A. Viergever , Alexander Leemans

A reliable Ultrasound (US)-to-US registration method to compensate for brain shift would substantially improve Image-Guided Neurological Surgery. Developing such a registration method is very challenging, due to factors such as missing…