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We propose to learn a low-dimensional probabilistic deformation model from data which can be used for registration and the analysis of deformations. The latent variable model maps similar deformations close to each other in an encoding…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Julian Krebs , Hervé Delingette , Boris Mailhé , Nicholas Ayache , Tommaso Mansi

Diffeomorphic image registration (DIR) is a fundamental task in 3D medical image analysis that seeks topology-preserving deformations between image pairs. To ensure diffeomorphism, a common approach is to model the deformation field as the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Mohammadjavad Matinkia , Nilanjan Ray

Image registration techniques usually assume that the images to be registered are of a certain type (e.g. single- vs. multi-modal, 2D vs. 3D, rigid vs. deformable) and there lacks a general method that can work for data under all…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Quang Luong Nhat Nguyen , Ruiming Cao , Laura Waller

Accurate image registration is essential in many medical imaging applications, yet most deep registration networks provide little indication of when or where their predictions are unreliable. Existing uncertainty estimation approaches, such…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Lin Tian , Xiaoling Hu , Juan Eugenio Iglesias

Deformable image registration is a fundamental task in medical image analysis, aiming to establish a dense and non-linear correspondence between a pair of images. Previous deep-learning studies usually employ supervised neural networks to…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Jun Zhang

We introduce SparseVM, a method that registers clinical-quality 3D MR scans both faster and more accurately than previously possible. Deformable alignment, or registration, of clinical scans is a fundamental task for many clinical…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Kathleen M. Lewis , Natalia S. Rost , John Guttag , Adrian V. Dalca

Parametric spatial transformation models have been successfully applied to image registration tasks. In such models, the transformation of interest is parameterized by a fixed set of basis functions as for example B-splines. Each basis…

Computer Vision and Pattern Recognition · Computer Science 2019-06-25 Robin Sandkühler , Simon Andermatt , Grzegorz Bauman , Sylvia Nyilas , Christoph Jud , Philippe C. Cattin

In recent years, neuroimaging has undergone a paradigm shift, moving away from the traditional brain mapping approach toward developing integrated, multivariate brain models that can predict categories of mental events. However, large…

Applications · Statistics 2022-09-19 Guoqing Wang , Abhirup Datta , Martin A. Lindquist

Deformable registration of magnetic resonance images between patients with brain tumors and healthy subjects has been an important tool to specify tumor geometry through location alignment and facilitate pathological analysis. Since tumor…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Xiaofeng Liu , Fangxu Xing , Chao Yang , C. -C. Jay Kuo , Georges ElFakhri , Jonghye Woo

This paper presents a framework for automatically learning shape and appearance models for medical (and certain other) images. It is based on the idea that having a more accurate shape and appearance model leads to more accurate image…

Computer Vision and Pattern Recognition · Computer Science 2019-05-29 John Ashburner , Mikael Brudfors , Kevin Bronik , Yael Balbastre

This paper presents a novel mathematical framework for representing uncertainty in large deformation diffeomorphic image registration. The Bayesian posterior distribution over the deformations aligning a moving and a fixed image is…

Computer Vision and Pattern Recognition · Computer Science 2017-01-13 Demian Wassermann , Matt Toews , Marc Niethammer , William Wells

Deformable image registration poses a challenging problem where, unlike most deep learning tasks, a complex relationship between multiple coordinate systems has to be considered. Although data-driven methods have shown promising…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Vasiliki Sideri-Lampretsa , Nil Stolt-Ansó , Huaqi Qiu , Julian McGinnis , Wenke Karbole , Martin Menten , Daniel Rueckert

Deep learning-based methods have recently demonstrated promising results in deformable image registration for a wide range of medical image analysis tasks. However, existing deep learning-based methods are usually limited to small…

Image and Video Processing · Electrical Eng. & Systems 2020-07-01 Tony C. W. Mok , Albert C. S. Chung

Deformable registration is one of the most challenging task in the field of medical image analysis, especially for the alignment between different sequences and modalities. In this paper, a non-rigid registration method is proposed for 3D…

Computer Vision and Pattern Recognition · Computer Science 2020-02-27 Xiaoyue Zhang , Weijian Jian , Yu Chen , Shihting Yang

Uncertainty quantification plays an important role in achieving trustworthy and reliable learning-based computational imaging. Recent advances in generative modeling and Bayesian neural networks have enabled the development of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-07 Canberk Ekmekci , Mujdat Cetin

Analysis of longitudinal changes in imaging studies often involves both segmentation of structures of interest and registration of multiple timeframes. The accuracy of such analysis could benefit from a tailored framework that jointly…

Computer Vision and Pattern Recognition · Computer Science 2021-02-25 Bo Li , Wiro J. Niessen , Stefan Klein , M. Arfan Ikram , Meike W. Vernooij , Esther E. Bron

Multimodal groupwise registration aligns internal structures in a group of medical images. Current approaches to this problem involve developing similarity measures over the joint intensity profile of all images, which may be…

Computer Vision and Pattern Recognition · Computer Science 2022-12-13 Xin Wang , Xinzhe Luo , Xiahai Zhuang

We examine in this paper the problem of image registration from the new perspective where images are given by sparse approximations in parametric dictionaries of geometric functions. We propose a registration algorithm that looks for an…

Computer Vision and Pattern Recognition · Computer Science 2013-12-31 Alhussein Fawzi , Pascal Frossard

The paper adapts the large deformation diffeomorphic metric mapping framework for image registration to the indirect setting where a template is registered against a target that is given through indirect noisy observations. The registration…

Numerical Analysis · Mathematics 2019-11-06 Chong Chen , Ozan Öktem

We propose a fluid-based registration framework of medical images based on implicit neural representation. By integrating implicit neural representation and Large Deformable Diffeomorphic Metric Mapping (LDDMM), we employ a Multilayer…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Chulong Zhang , Xiaokun Liang