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We demonstrate that a deep neural network can significantly improve optical microscopy, enhancing its spatial resolution over a large field-of-view and depth-of-field. After its training, the only input to this network is an image acquired…

Machine Learning · Computer Science 2017-11-21 Yair Rivenson , Zoltan Gorocs , Harun Gunaydin , Yibo Zhang , Hongda Wang , Aydogan Ozcan

Optical aberrations prevent telescopes from reaching their theoretical diffraction limit. Once estimated, these aberrations can be compensated for using deformable mirrors in a closed loop. Focal plane wavefront sensing enables the…

The quality of microscopy images often suffers from optical aberrations. These aberrations and their associated point spread functions have to be quantitatively estimated to restore aberrated images. The recent state-of-the-art method…

Image and Video Processing · Electrical Eng. & Systems 2022-11-22 Kira Vinogradova , Eugene W. Myers

Most current single image camera calibration methods rely on specific image features or user input, and cannot be applied to natural images captured in uncontrolled settings. We propose directly inferring camera calibration parameters from…

Computer Vision and Pattern Recognition · Computer Science 2018-04-24 Yannick Hold-Geoffroy , Kalyan Sunkavalli , Jonathan Eisenmann , Matt Fisher , Emiliano Gambaretto , Sunil Hadap , Jean-François Lalonde

Modern cameras with large apertures often suffer from a shallow depth of field, resulting in blurry images of objects outside the focal plane. This limitation is particularly problematic for fixed-focus cameras, such as those used in smart…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Xinge Yang , Chuong Nguyen , Wenbin Wang , Kaizhang Kang , Wolfgang Heidrich , Xiaoxing Li

Scene depth estimation from stereo and monocular imagery is critical for extracting 3D information for downstream tasks such as scene understanding. Recently, learning-based methods for depth estimation have received much attention due to…

Computer Vision and Pattern Recognition · Computer Science 2021-10-12 Zhaoshuo Li , Nathan Drenkow , Hao Ding , Andy S. Ding , Alexander Lu , Francis X. Creighton , Russell H. Taylor , Mathias Unberath

Aberrations limit scanning fluorescence microscopy when imaging in scattering materials such as biological tissue. Model-based approaches for adaptive optics take advantage of a computational model of the optical setup. Such models can be…

Optics · Physics 2021-07-07 Ivan Vishniakou , Johannes D. Seelig

This paper presents a deep learning-based estimation of the intensity component of MultiSpectral bands by considering joint multiplication of the neighbouring spectral bands. This estimation is conducted as part of the component…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Arian Azarang , Nasser Kehtarnavaz

The usefulness of deep learning models in robotics is largely dependent on the availability of training data. Manual annotation of training data is often infeasible. Synthetic data is a viable alternative, but suffers from domain gap. We…

Computer Vision and Pattern Recognition · Computer Science 2022-11-18 Benedikt T. Imbusch , Max Schwarz , Sven Behnke

Reliable and accurate lane detection has been a long-standing problem in the field of autonomous driving. In recent years, many approaches have been developed that use images (or videos) as input and reason in image space. In this paper we…

Computer Vision and Pattern Recognition · Computer Science 2019-05-07 Min Bai , Gellert Mattyus , Namdar Homayounfar , Shenlong Wang , Shrinidhi Kowshika Lakshmikanth , Raquel Urtasun

One of the primary sources of suboptimal image quality in ultrasound imaging is phase aberration. It is caused by spatial changes in sound speed over a heterogeneous medium, which disturbs the transmitted waves and prevents coherent…

Image and Video Processing · Electrical Eng. & Systems 2024-07-03 Mostafa Sharifzadeh , Sobhan Goudarzi , An Tang , Habib Benali , Hassan Rivaz

Deep neural networks have been very successful in image estimation applications such as compressive-sensing and image restoration, as a means to estimate images from partial, blurry, or otherwise degraded measurements. These networks are…

Computer Vision and Pattern Recognition · Computer Science 2019-10-30 Zhihao Xia , Ayan Chakrabarti

Deep learning has been proven to yield reliably generalizable answers to numerous classification and decision tasks. Here, we demonstrate for the first time, to our knowledge, that deep neural networks (DNNs) can be trained to solve inverse…

Computer Vision and Pattern Recognition · Computer Science 2017-06-27 Ayan Sinha , Justin Lee , Shuai Li , George Barbastathis

Deep neural networks have emerged as effective tools for computational imaging including quantitative phase microscopy of transparent samples. To reconstruct phase from intensity, current approaches rely on supervised learning with training…

Image and Video Processing · Electrical Eng. & Systems 2020-01-28 Emrah Bostan , Reinhard Heckel , Michael Chen , Michael Kellman , Laura Waller

We demonstrate a method for training a convolutional neural network with simulated images for usage on real-world experimental data. Modern machine learning methods require large, robust training data sets to generate accurate predictions.…

Soft Condensed Matter · Physics 2019-08-15 Eric N. Minor , Stian D. Howard , Adam A. S. Green , Cheol S. Park , Noel A. Clark

In the rapidly evolving field of optical engineering, precise alignment of multi-lens imaging systems is critical yet challenging, as even minor misalignments can significantly degrade performance. Traditional alignment methods rely on…

Optics · Physics 2025-07-01 Tomer Slor , Dean Oren , Shira Baneth , Tom Coen , Haim Suchowski

The impressive growth of data throughput in optical microscopy has triggered a widespread use of supervised learning (SL) models running on compressed image datasets for efficient automated analysis. However, since lossy image compression…

High-throughput 2D and 3D scanning electron microscopy, which relies on automation and dependable control algorithms, requires high image quality with minimal human intervention. Classical focus and astigmatism correction algorithms attempt…

Instrumentation and Detectors · Physics 2023-05-10 Philipp Johannes Schubert , Rangoli Saxena , Joergen Kornfeld

Volumetric imaging by fluorescence microscopy is often limited by anisotropic spatial resolution from inferior axial resolution compared to the lateral resolution. To address this problem, here we present a deep-learning-enabled…

Computer Vision and Pattern Recognition · Computer Science 2022-07-06 Hyoungjun Park , Myeongsu Na , Bumju Kim , Soohyun Park , Ki Hean Kim , Sunghoe Chang , Jong Chul Ye

This work presents a probabilistic deep neural network that combines LiDAR point clouds and RGB camera images for robust, accurate 3D object detection. We explicitly model uncertainties in the classification and regression tasks, and…

Robotics · Computer Science 2020-02-04 Di Feng , Yifan Cao , Lars Rosenbaum , Fabian Timm , Klaus Dietmayer
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