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We study the problem of allocating scarce societal resources of different types (e.g., permanent housing, deceased donor kidneys for transplantation, ventilators) to heterogeneous allocatees on a waitlist (e.g., people experiencing…

Optimization and Control · Mathematics 2025-08-13 Bill Tang , Çağıl Koçyiğit , Eric Rice , Phebe Vayanos

Health-policy planning requires evidence on the burden that epidemics place on healthcare systems. Multiple, often dependent, datasets provide a noisy and fragmented signal from the unobserved epidemic process including transmission and…

Applications · Statistics 2024-09-11 Alice Corbella , Anne M Presanis , Paul J Birrell , Daniela De Angelis

We consider multiple diseases spreading in a static Configuration Model network. We make standard assumptions that infection transmits from neighbor to neighbor at a disease-specific rate and infected individuals recover at a…

Populations and Evolution · Quantitative Biology 2015-06-11 Joel C. Miller

Background: The 2014 Ebola outbreak in West Africa was the largest on record, resulting in over 25,000 total infections and 15,000 total deaths. Mathematical modeling can be used to investigate the mechanisms driving transmission during…

Populations and Evolution · Quantitative Biology 2017-09-22 Michael A. L. Hayashi , Marisa C. Eisenberg

We consider the problem of optimizing locations of distribution centers (DCs) and plans for distributing resources such as test kits and vaccines, under spatiotemporal uncertainties of disease spread and demand for the resources. We aim to…

Optimization and Control · Mathematics 2022-07-19 Beste Basciftci , Xian Yu , Siqian Shen

We study the impact of model parameter uncertainty on optimally mitigating the spread of epidemics. We capture the epidemic spreading process using a susceptible-infected-removed (SIR) epidemic model and consider testing for isolation as…

Systems and Control · Electrical Eng. & Systems 2022-09-07 Baike She , Shreyas Sundaram , Philip E. Paré

The rapid development of the mobile Internet and the Internet of Things is leading to a diversification of user devices and the emergence of new mobile applications on a regular basis. Such applications include those that are…

Computational Engineering, Finance, and Science · Computer Science 2024-08-13 Xirui Tang , Zeyu Wang , Xiaowei Cai , Honghua Su , Changsong Wei

We propose a theoretical framework for the study of epidemics in structured metapopulations, with heterogeneous agents, subjected to recurrent mobility patterns. We propose to represent the heterogeneity in the composition of the…

Physics and Society · Physics 2018-08-15 David Soriano-Paños , Laura Lotero , Jesús Gómez-Gardeñes , Alex Arenas

Understanding how human mobility and information propagation influence the course of an epidemic remains a key challenge in digital epidemiology. In this work, we develop a new awareness-based, event-triggered epidemic model embedded within…

Physics and Society · Physics 2026-05-06 Yusheng Li , Minyu Feng , Liang-jian Deng , Matjaž Perc , Jürgen Kurths

Ebola virus disease is a lethal human and primate disease that currently requires a particular attention from the international health authorities due to important outbreaks in some Western African countries and isolated cases in the United…

Populations and Evolution · Quantitative Biology 2015-05-13 Benjamin Ivorra , Diène Ngom , Ángel Manuel Ramos

The spatial structure of populations is a key element in the understanding of the large scale spreading of epidemics. Motivated by the recent empirical evidence on the heterogeneous properties of transportation and commuting patterns among…

Populations and Evolution · Quantitative Biology 2008-03-19 Vittoria Colizza , Alessandro Vespignani

Data intensive applications often involve the analysis of large datasets that require large amounts of compute and storage resources. While dedicated compute and/or storage farms offer good task/data throughput, they suffer low resource…

Distributed, Parallel, and Cluster Computing · Computer Science 2008-08-27 Ioan Raicu , Yong Zhao , Ian Foster , Alex Szalay

We study a multi-objective model on the allocation of reusable resources under model uncertainty. Heterogeneous customers arrive sequentially according to a latent stochastic process, request for certain amounts of resources, and occupy…

Optimization and Control · Mathematics 2023-08-02 Xilin Zhang , Wang Chi Cheung

Edge computing (EC) promises to deliver low-latency and ubiquitous computation to numerous devices at the network edge. This paper aims to jointly optimize edge node (EN) placement and resource allocation for an EC platform, considering…

Optimization and Control · Mathematics 2024-01-17 Jiaming Cheng , Duong Thuy Anh Nguyen , Duong Tung Nguyen

Understanding the dynamics of the spread of diseases within populations is critical for effective public health interventions. We extend the classical SIR model by incorporating additional complexities such as the introduction of a cure and…

Populations and Evolution · Quantitative Biology 2025-10-30 Daniel Perkins , Davis Hunter , Drake Brown , Trevor Garrity , Wyatt Pochman

Nowadays, epidemic models provide an appropriate tool for describing the propagation of biological viruses in human or animal populations, or rumours and other kinds of information in social networks and malware in both computer and ad hoc…

Optimization and Control · Mathematics 2020-07-21 Vladislav Taynitskiy , Elena Gubar , Denis Fedyanin , Ilya Petrov , Quanyan Zhu

Clinical decision support tools rooted in machine learning and optimization can provide significant value to healthcare providers, including through better management of intensive care units. In particular, it is important that the patient…

Machine Learning · Computer Science 2021-12-20 Fernando Lejarza , Jacob Calvert , Misty M Attwood , Daniel Evans , Qingqing Mao

This paper investigates the dynamics of infectious diseases with a non-exponentially distributed infectious period. This is achieved by considering a multi-stage infection model on networks. Using pairwise approximation with a standard…

Physics and Society · Physics 2015-11-23 N. Sherborne , K. B. Blyuss , I. Z. Kiss

We study the optimal control problem of allocating campaigning resources over the campaign duration and degree classes in a social network. Information diffusion is modeled as a Susceptible-Infected epidemic and direct recruitment of…

Social and Information Networks · Computer Science 2016-10-27 Kundan Kandhway , Joy Kuri

Since early 2020, the world has been dealing with a raging pandemic outbreak: COVID-19. A year later, vaccines have become accessible, but in limited quantities, so that governments needed to devise a strategy to decide which part of the…

Populations and Evolution · Quantitative Biology 2022-04-13 Sander Tonkens , Paul de Klaver , Mauro Salazar