Related papers: Data-Driven Infectious Disease Control with Uncert…
Existing compartmental models in epidemiology are limited in terms of optimizing the resource allocation to control an epidemic outbreak under disease growth uncertainty. In this study, we address this core limitation by presenting a…
The Ebola epidemic in West Africa is the largest ever recorded, with over 27,000 cases and 11,000 deaths as of June 2015. The public health response was challenged by difficulties with disease surveillance, which impacted subsequent…
In 2014, a major epidemic of human Ebola virus disease emerged in West Africa, where human-to-human transmission has now been been sustained for greater than 10 months. In the summer of 2014, there was great uncertainty about the answers to…
Frequent emergence of communicable diseases has been a major concern worldwide. Lack of sufficient resources to mitigate the disease-burden makes the situation even more challenging for lower-income countries. Hence, strategy development…
A modified, deterministic SEIR model is developed for the 2014 Ebola epidemic occurring in the West African nations of Guinea, Liberia, and Sierra Leone. The model describes the dynamical interaction of susceptible and infected populations,…
Connecting the different scales of epidemic dynamics, from individuals to communities to nations, remains one of the main challenges of disease modeling. Here, we revisit one of the largest public health efforts deployed against a localized…
We study the problem of allocating limited supply of medical resources in developing countries, in particular, Sierra Leone. We address this problem by combining machine learning (to predict demand) with optimization (to optimize…
As an emergent infectious disease outbreak unfolds, public health response is reliant on information on key epidemiological quantities, such as transmission potential and serial interval. Increasingly, transmission models fit to incidence…
An Ebola outbreak of unparalleled size is currently affecting several countries in West Africa, and international efforts to control the outbreak are underway. However, the efficacy of these interventions, and their likely impact on an…
Resource support between individuals is of particular importance in controlling or mitigating epidemic spreading, especially during pandemics. Whereas there remains the question of how we can protect ourselves from being infected while…
We focus on the problem of uncertainty informed allocation of medical resources (vaccines) to heterogeneous populations for managing epidemic spread. We tackle two related questions: (1) For a compartmental ordinary differential equation…
The data for the Ebola outbreak that occurred in 2014-2016 in three countries of West Africa are analysed within a common framework. The analysis is made using the results of an agent based Susceptible-Infected-Removed (SIR) model on a…
A differential equations model is developed for the 2014 Ebola epidemics in Sierra Leone, Liberia, and Guinea. The model describes the dynamic interactions of the susceptible and infected populations of these countries. The model…
Under the Dynamic Resource Allocation (DRA) model, an administrator has the mission to allocate dynamically a limited budget of resources to the nodes of a network in order to reduce a diffusion process (DP) (e.g. an epidemic). The standard…
We present a distributed resource allocation strategy to control an epidemic outbreak in a networked population based on a Distributed Alternating Direction Method of Multipliers (D-ADMM) algorithm. We consider a linearized Susceptible-…
In the Dynamic Resource Allocation (DRA) problem, an administrator has to allocate a limited amount of resources to the nodes of a network in order to reduce a diffusion process (DP) (e.g. an epidemic). In this paper we propose a…
In the context of epidemiology, policies for disease control are often devised through a mixture of intuition and brute-force, whereby the set of logically conceivable policies is narrowed down to a small family described by a few…
We present a mathematical analysis of the early detection of Ebola virus. The propagation of the virus is analysed by using a Susceptible, Infected, Recovered (SIR) model. In order to provide useful predictions about the potential…
The 2014 Ebola outbreak in west Africa raised many questions about the control of infectious disease in an increasingly connected global society. Limited availability of contact information made contact tracing difficult or impractical in…
Epidemics are a serious public health threat, and the resources for mitigating their effects are typically limited. Decision-makers face challenges in forecasting the supply and demand for these resources as prior information about the…