Related papers: Integer topological defects of cell monolayers -- …
Classical elasticity is concerned with bodies that can be modeled as smooth manifolds endowed with a reference metric that represents local equilibrium distances between neighboring material elements. The elastic energy associated with a…
We show that back-flow, the coupling between the order parameter and the velocity fields, has a significant effect on the motion of defects in nematic liquid crystals. In particular the defect speed can depend strongly on the topological…
Topological defects are a ubiquitous phenomenon in diverse physical systems. In nematic liquid crystals (LCs), they are dynamic, physicochemically distinct, sensitive to stimuli, and are thereby promising for a range of applications.…
This study theoretically investigates how anisotropic curved membrane components (CMCs) control vesicle morphology through curvature sensing, nematic alignment, topological defects, and volume constraints. By comparing arc-shaped and…
In cell extrusion, a cell embedded in an epithelial monolayer loses its apical or basal surface and is subsequently squeezed out of the monolayer by neighboring cells. Cell extrusions occur during apoptosis, epithelial-mesenchymal…
Topological defects in active liquid crystals can be confined by introducing gradients of activity. Here, we examine the dynamical behavior of two defects confined by a sharp gradient of activity that separates an active circular region and…
Coherent angular rotation of epithelial cells is thought to contribute to many vital physiological processes including tissue morphogenesis and glandular formation. However, factors regulating this motion, and the implications of this…
Cell monolayers are a central model system to tissue biophysics. In vivo, epithelial tissues are curved on the scale of microns, and curvature's role in the onset of spontaneous tissue flows is still not well-understood. Here, we present a…
We characterise the particlelike kinematics of charge-carrying topological defects in nematic media via a geometric field theory. This differs from the theory of electromagnetism, with which it is often compared, due to the absence of…
We investigate experimentally and numerically the defect configurations emerging when a cholesteric liquid crystal is confined to a spherical shell. We uncover a rich scenario of defect configurations, some of them non-existent in nematic…
Cell layers are often categorized as contractile or extensile active nematics but recent experiments on neural progenitor cells with induced $+1$ topological defects challenge this classification. In a bottom-up approach, we first study a…
Topological defects play a key role in two-dimensional active nematics, and a transient role in two-dimensional active polar fluids. In this paper, we study both the transient and long-time behavior of defects in two-dimensional active…
Polar active matter - including animal herds, aggregates of motile cells and active colloids - often forms coordinated migration patterns, such as flocking. This orderly motion can be disrupted by full-integer topological defects…
A rich variety of specific multidomain textures recently observed in antiferromagnetically coupled multilayers with perpendicular anisotropy include regular (equilibrium) multidomain states as well as different types of topological magnetic…
Epithelial cell monolayers exhibit traveling mechanical waves. We rationalize this observation thanks to a hydrodynamic description of the monolayer as a compressible, active and polar material. We show that propagating waves of the cell…
We study long-range morphological changes in atomic monolayers on solid substrates induced by different types of defects; e.g., by monoatomic steps in the surface, or by the tip of an atomic force microscope (AFM), placed at some distance…
Active matter is characterized by its ability to induce motion by self-generated stress. In the case of a solid, such motion can lead to shape transformations. The stress-generating components can be anisotropic endowing the material with…
To enhance the understanding of the behavior of active nematic, it is important to understand the behavior of topological defects. In this paper, we study the configuration of topological defects of a two-dimensional active nematic around a…
We investigate the geometrical and mechanical properties of adherent cells characterized by a highly anisotropic actin cytoskeleton. Using a combination of theoretical work and experiments on micropillar arrays, we demonstrate that the…
Cultured stem cells have become a standard platform not only for regenerative medicine and developmental biology but also for biophysical studies. Yet, the characterization of cultured stem cells at the level of morphology and macroscopic…