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Magnetic nanoparticle hyperthermia is an attractive emerging cancer treatment, but the acting microscopic energy deposition mechanisms are not well understood and optimization suffers. We describe several approximate forms for the…

Mesoscale and Nanoscale Physics · Physics 2014-03-26 Daniel B. Reeves , John B. Weaver

Magnetic hyperthermia is an adjuvant therapy for cancer where injected magnetic nanoparticles are used to transfer energy from the time-dependent applied magnetic field into the surrounding medium. Its main importance is to be able to…

Soft Condensed Matter · Physics 2022-03-09 Zs. Iszaly , I. Gresits , I. G. Marian , Gy. Thuroczy , O. Sagi , B. G. Markus , F. Simon , I. Nandori

Magnetospirillum gryphiswaldense is a microorganism with the ability to biomineralize magnetite nanoparticles, called magnetosomes, and arrange them into a chain that behaves like a magnetic compass. Rather than straight lines, magnetosome…

The results of large-scale simulations investigating the dynamics of magnetization reversal in arrays of single-domain nanomagnets after a rapid reversal of the applied field at nonzero temperature are presented. The numerical micromagnetic…

Materials Science · Physics 2009-10-31 Gregory Brown , M. A. Novotny , Per Arne Rikvold

Experiments show that cellular uptake of nanoparticles, via receptor-mediated endocytosis, strongly depends on nanoparticle size. There is an optimal size, approximately 50 nm in diameter, at which cellular uptake is the highest. In…

Subcellular Processes · Quantitative Biology 2014-11-27 Anand Banerjee , Alexander Berzhkovskii , Ralph Nossal

Magnetic hyperthermia is a new type of cancer treatment designed for overcoming resistance to chemotherapy during the treatment of solid, inaccessible human tumors. The main challenge of this technology is increasing the local tumoral…

Tissues and Organs · Quantitative Biology 2016-11-09 Beatriz Sanz , M. Pilar Calatayud , Teobaldo E. Torres , Mónica L. Fanarraga , M. Ricardo Ibarra , Gerardo F. Goya

The use of drugs or radiation to attack cancerous cells often leaves the treatment material within the body where it could affect healthy cells or damages healthy tissue; as is the case with traditional invasive surgery. An alternative…

Biological Physics · Physics 2022-06-14 Derek Michael Forrester

Magnetotactic bacteria (MTB) are of significant interest for biophysical applications, particularly in cancer treatment. The biomineralized magnetosomes produced by these bacteria are high-quality magnetic nanoparticles that form chains…

Understanding the influence of dipolar interactions in magnetic hyperthermia (MH) experiments is of crucial importance for a fine optimization of nanoparticle (NP) heating power. In this study, we use a kinetic Monte-Carlo algorithm to…

Materials Science · Physics 2015-06-22 R. P. Tan , J. Carrey , M. Respaud

This chapter provides an introduction to the fundamental physical ideas and models relevant to the phenomenon of magnetic hysteresis in nanoparticle assemblies. The concepts of single-domain particles and superparamagnetism are discussed.…

Mesoscale and Nanoscale Physics · Physics 2010-04-15 D. Kechrakos

Magnetization reversal in magnetic nanostructures is investigated numerically over time-scales ranging from fast switching processes on a picosecond scale to thermally activated reversal on a microsecond time-scale. A simulation of the…

Statistical Mechanics · Physics 2015-06-24 D. Hinzke , U. Nowak

Magnetic nanoparticle-based hyperthermia has emerged as a promising therapeutic modality for treating malignant solid tumors that exhibit resistance to conventional cancer treatments, including chemotherapy and radiation. Despite the…

Mesoscale and Nanoscale Physics · Physics 2024-08-21 S. Scheibler , H. Wei , J. Ackers , S. Helbig , S. Koraltan , R. Peremadathil-Pradeep , M. Krupiński , M. Graeser , D. Suess , I. K. Herrmann , H. J. Hug

We calculate the magnetization hysteresis for an ordered array of composite magnetic nanoparticles with a ferromagnetic (FM) core and an antiferromagnetic (AFM) shell, located on a triangular lattice and coupled via magnetostatic forces.…

Materials Science · Physics 2007-07-25 D. Kechrakos , K. N. Trohidou , M. Vasilakaki

Iron oxide (e.g., Fe$_3$O$_4$ or Fe$_2$O$_3$) nanoparticles are promising candidates for a variety of biomedical applications ranging from magnetic hyperthermia therapy to drug delivery and bio-detection, due to their superparamagnetism,…

Understanding high-field amplitude electromagnetic heat loss phenomena is of great importance, in particular in the biomedical field, since the heat-delivery treatment plans might rely on analytical models that are only valid at low field…

Mesoscale and Nanoscale Physics · Physics 2017-05-24 Marcus S. Carrião , Victor R. R. Aquino , Gabriel T. Landi , Ediron L. Verde , Marcelo H. Sousa , Andris F. Bakuzis

Numerical integration of a stochastic Landau-Lifshitz-Gilbert equation is used to study dynamic processes in single-domain nanoscale magnets at nonzero temperatures. Special attention is given to including thermal fluctuations as a Langevin…

Materials Science · Physics 2009-10-31 Gregory Brown , M. A. Novotny , Per Arne Rikvold

An efficient method for computing thermodynamic equilibrium states at the micromagnetic length scale is introduced, using the Markov chain Monte Carlo method. Trial moves include not only rotations of vectors, but also a change in their…

Mesoscale and Nanoscale Physics · Physics 2021-11-10 Serban Lepadatu

Nowadays, magnetic hyperthermia constitutes a complementary approach to cancer treatment. The use of magnetic particles as heating mediators, proposed in the 1950s, provides a novel strategy for improving tumor treatment and, consequently,…

The high frequency magnetic permeability of nanocomposite film consisting of the single-domain spherical ferromagnetic particles in the dielectric matrix is studied. The permeability is assumed to be determined by rotation of the…

Other Condensed Matter · Physics 2009-11-10 N. A. Buznikov , I. T. Iakubov , A. L. Rakhmanov , A. O. Sboychakov

Micromanipulation of magnetotactic bacteria with a microelectromagnet matrix was demonstrated. Magnetotactic bacteria synthesize a chain of magnetic nanoparticles inside their body to guide their motion in the geomagnetic field. A…

Other Condensed Matter · Physics 2007-05-23 H. Lee , A. M. Purdon , V. Chu , R. M. Westervelt