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In vitro fertilization (IVF) is a widely utilized assisted reproductive technology, yet predicting its success remains challenging due to the multifaceted interplay of clinical, demographic, and procedural factors. This study develops a…

In clinical In-Vitro Fertilization (IVF), identifying the most viable embryo for transfer is important to increasing the likelihood of a successful pregnancy. Traditionally, this process involves embryologists manually assessing embryos'…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Junsik Kim , Zhiyi Shi , Davin Jeong , Johannes Knittel , Helen Y. Yang , Yonghyun Song , Wanhua Li , Yicong Li , Dalit Ben-Yosef , Daniel Needleman , Hanspeter Pfister

A major challenge in clinical In-Vitro Fertilization (IVF) is selecting the highest quality embryo to transfer to the patient in the hopes of achieving a pregnancy. Time-lapse microscopy provides clinicians with a wealth of information for…

The selection of the optimal embryo for transfer is a critical yet challenging step in in vitro fertilization (IVF), primarily due to its reliance on the manual inspection of extensive time-lapse imaging data. A key obstacle in this process…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Zahra Asghari Varzaneh , Niclas Wölner-Hanssen , Reza Khoshkangini , Thomas Ebner , Magnus Johnsson

Globally, infertility rates are increasing, with 2.5\% of all births being assisted by in vitro fertilisation (IVF) in 2022. Male infertility is the cause for approximately half of these cases. The quality of sperm DNA has substantial…

Machine Learning · Computer Science 2025-02-13 Byron A Jacobs , Ifthakaar Shaik , Frando Lin

Assessing and selecting the most viable embryos for transfer is an essential part of in vitro fertilization (IVF). In recent years, several approaches have been made to improve and automate the procedure using artificial intelligence (AI)…

Machine Learning · Computer Science 2022-04-06 Jørgen Berntsen , Jens Rimestad , Jacob Theilgaard Lassen , Dang Tran , Mikkel Fly Kragh

Tens of millions of women suffer from infertility worldwide each year. In vitro fertilization (IVF) is the best choice for many such patients. However, IVF is expensive, time-consuming, and both physically and emotionally demanding. The…

Quantitative Methods · Quantitative Biology 2019-11-12 Bo Zhang , Yuqi Cui , Meng Wang , Jingjing Li , Lei Jin , Dongrui Wu

In Vitro Fertilization (IVF) is the most widely used Assisted Reproductive Technology (ART). IVF usually involves controlled ovarian stimulation, oocyte retrieval, fertilization in the laboratory with subsequent embryo transfer. The first…

Artificial Intelligence · Computer Science 2022-01-31 Xizhe Wang , Ning Zhang , Jia Wang , Jing Ni , Xinzi Sun , John Zhang , Zitao Liu , Yu Cao , Benyuan Liu

In conventional clinical in-vitro fertilization practices embryos are transferred either at the cleavage or blastocyst stages of development. Cleavage stage transfers, particularly, are beneficial for patients with relatively poor prognosis…

Embryo quality assessment after in vitro fertilization (IVF) is primarily done visually by embryologists. Variability among assessors, however, remains one of the main causes of the low success rate of IVF. This study aims to develop an…

Image and Video Processing · Electrical Eng. & Systems 2020-08-31 Ali Akbar Septiandri , Ade Jamal , Pritta Ameilia Iffanolida , Oki Riayati , Budi Wiweko

Infertility, a pressing global health concern, affects a substantial proportion of individuals worldwide. While advancements in assisted reproductive technology (ART) have offered effective interventions, conventional in vitro…

Artificial Intelligence · Computer Science 2025-09-25 Xueqiang Ouyang , Jia Wei

Embryo selection is one of multiple crucial steps in in-vitro fertilization, commonly based on morphological assessment by clinical embryologists. Although artificial intelligence methods have demonstrated their potential to support embryo…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Nicklas Neu , Thomas Ebner , Jasmin Primus , Bernhard Schenkenfelder , Raphael Zefferer , Mathias Brunbauer , Florian Kromp

Automating embryo viability prediction for in vitro fertilization (IVF) is important but challenging due to the limited availability of labeled pregnancy outcome data, as only a small fraction of embryos are labeled after transfer.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Zhiyi Shi , Junsik Kim , Helen Y. Yang , Yonghyun Song , Hyun-Jic Oh , Dalit Ben-Yosef , Daniel Needleman , Hanspeter Pfister

Artificial intelligence (AI) has emerged as a powerful tool to enhance decision-making and optimize treatment protocols in in vitro fertilization (IVF). In particular, AI shows significant promise in supporting decision-making during the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Jana Zakall , Birgit Pohn , Antonia Graf , Daniel Kovatchki , Arezoo Borji , Ragib Shahriar Islam , Hossam Haick , Heinz Strohmer , Sepideh Hatamikia

An important limitation to the development of Artificial Intelligence (AI)-based solutions for In Vitro Fertilization (IVF) is the absence of a public reference benchmark to train and evaluate deep learning (DL) models. In this work, we…

Image and Video Processing · Electrical Eng. & Systems 2022-05-16 Tristan Gomez , Magalie Feyeux , Nicolas Normand , Laurent David , Perrine Paul-Gilloteaux , Thomas Fréour , Harold Mouchère

Infertility has a considerable impact on individuals' quality of life, affecting them socially and psychologically, with projections indicating a rise in the upcoming years. In vitro fertilization (IVF) emerges as one of the primary…

A growing share of the world's population is being born via assisted reproductive technology (ART), including in-vitro fertilisation (IVF). However, two concerns persist. First, ART pregnancies correlate with predictors of poor outcomes at…

General Economics · Economics 2024-09-04 Fabio I. Martinenghi , Xian Zhang , Luk Rombauts , Georgina M. Chambers

Artificial intelligence has recently shown promise in automated embryo selection for In-Vitro Fertilization (IVF). However, current approaches either address partial embryo evaluation lacking holistic quality assessment or target clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Yong Sun , Yipeng Wang , Junyu Shi , Zhiyuan Zhang , Yanmei Xiao , Lei Zhu , Manxi Jiang , Qiang Nie

Videomicroscopy is a promising tool combined with machine learning for studying the early development of in vitro fertilized bovine embryos and assessing its transferability as soon as possible. We aim to predict the embryo transferability…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 Yasmine Hachani , Patrick Bouthemy , Elisa Fromont , Sylvie Ruffini , Ludivine Laffont , Alline de Paula Reis

In vitro fertilization (IVF) comprises a sequence of interventions concerned with the creation and culture of embryos which are then transferred to the patient's uterus. While the clinically important endpoint is birth, the responses to…

Applications · Statistics 2020-10-21 Jack Wilkinson , Stephen A Roberts , Andy Vail
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