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The objective of this paper is to present a Mixed Reality System (MRS) for rehabilitation of the upper limb after stroke. The system answers the following challenges: (i) increase motivation of patients by making the training a personalized…

Human-Computer Interaction · Computer Science 2010-11-09 Ines Di Loreto Ines , Abdelkader Gouaïch

Alzheimer's disease is the most common cause of dementia, yet difficult to accurately diagnose without the use of invasive techniques, particularly at the beginning of the disease. This work addresses the classification and analysis of…

Computer Vision and Pattern Recognition · Computer Science 2017-12-06 Wellington Pinheiro dos Santos , Ricardo Emmanuel de Souza , Ascendino Flávio Dias e Silva , Plínio Batista dos Santos Filho

Longitudinal fMRI datasets hold great promise for the study of neurodegenerative diseases, but realizing their potential depends on extracting accurate fMRI-based brain measures in individuals over time. This is especially true for rare,…

Shoulder disorders, such as frozen shoulder (a.k.a., adhesive capsulitis), are common conditions affecting the health of people worldwide, and have a high incidence rate among the elderly and workers engaged in repetitive shoulder tasks. In…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Jindong Hong , Wencheng Zhang , Shiqin Qiao , Jianhai Chen , Jianing Qiu , Chuanyang Zheng , Qian Xu , Yun Ji , Qianyue Wen , Weiwei Sun , Hao Li , Huizhen Li , Huichao Wang , Kai Wu , Meng Li , Yijun He , Lingjie Luo , Jiankai Sun

Alzheimer's disease is the most common neurodegenerative disease. The aim of this study is to infer structural changes in brain connectivity resulting from disease progression using cortical thickness measurements from a cohort of…

Effect modification occurs while the effect of the treatment is not homogeneous across the different strata of patient characteristics. When the effect of treatment may vary from individual to individual, precision medicine can be improved…

Dementia is a collection of symptoms associated with impaired cognition and impedes everyday normal functioning. Dementia, with Alzheimer's disease constituting its most common type, is highly complex in terms of etiology and…

Multiple Sclerosis (MS) is a chronic progressive neurological disease characterized by the development of lesions in the white matter of the brain. T2-fluid-attenuated inversion recovery (FLAIR) brain magnetic resonance imaging (MRI)…

Image and Video Processing · Electrical Eng. & Systems 2022-09-12 Jueqi Wang , Derek Berger , Erin Mazerolle , Othman Soufan , Jacob Levman

We use X-ray phase-contrast tomography (XPCT) in a multi-organ approach to identify early imaging markers predictive of multiple sclerosis (MS) in EAE animal model. As the majority of neurodegenerative diseases, MS is characterized by a…

Liver cirrhosis is a major global health problem causing millions of deaths annually, and timely detection with aggressive treatment can significantly improve patients' quality of life. Modelling complex diseases from biomedical data is…

Other Quantitative Biology · Quantitative Biology 2026-04-29 Xueyuan Huang , Yuheng Wang , Yuanzhi He , Siqi Gou , Lu Bai , Wenqian Wu , Peifeng Liu , Aijia Wang , Tianhui Fan , Ze Zhou , Jiayu Xu

Importance: The prevalence of severe mental illnesses (SMIs) in the United States is approximately 3% of the whole population. The ability to conduct risk screening of SMIs at large scale could inform early prevention and treatment.…

Artificial Intelligence · Computer Science 2023-01-13 Dianbo Liu , Karmel W. Choi , Paulo Lizano , William Yuan , Kun-Hsing Yu , Jordan W. Smoller , Isaac Kohane

There is a growing proportion of people with several disease conditions ("multimorbidity"), placing increasing demands on healthcare systems. One hypothesis is that clusters of diseases may arise from shared underlying disease processes…

Methodology · Statistics 2025-08-15 Anthony J. Webster

We present a real-time visualization system for Transcranial Magnetic Stimulation (TMS), a non-invasive neuromodulation technique for treating various brain disorders and mental health diseases. Our solution targets the current challenges…

Signal Processing · Electrical Eng. & Systems 2024-03-14 Loraine Franke , Tae Young Park , Jie Luo , Yogesh Rathi , Steve Pieper , Lipeng Ning , Daniel Haehn

Introduction Quantum Convolutional Neural Network (QCNN)-Long Short-Term Memory (LSTM) models were studied to provide sequential relationships for each timepoint in MRIs of patients with Multiple Sclerosis (MS). In this pilot study, we…

Machine Learning · Computer Science 2024-01-23 John D. Mayfield , Issam El Naqa

Multiple Sclerosis (MS) is a severe neurological disease characterized by inflammatory lesions in the central nervous system. Hence, predicting inflammatory disease activity is crucial for disease assessment and treatment. However, MS…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 Chinmay Prabhakar , Hongwei Bran Li , Johannes C. Paetzold , Timo Loehr , Chen Niu , Mark Mühlau , Daniel Rueckert , Benedikt Wiestler , Bjoern Menze

Vision disorders significantly impact millions of lives, altering how visual information is processed and perceived. In this work, a computational framework was developed using the BrokenEyes system to simulate five common eye disorders:…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Prottay Kumar Adhikary

Deep learning (DL) networks have recently been shown to outperform other segmentation methods on various public, medical-image challenge datasets [3,11,16], especially for large pathologies. However, in the context of diseases such as…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Tanya Nair , Doina Precup , Douglas L. Arnold , Tal Arbel

Objective: Multiple Sclerosis (MS) is an autoimmune, and demyelinating disease that leads to lesions in the central nervous system. This disease can be tracked and diagnosed using Magnetic Resonance Imaging (MRI). Up to now a multitude of…

Image and Video Processing · Electrical Eng. & Systems 2022-01-07 Mehdi SadeghiBakhi , Hamidreza Pourreza , Hamidreza Mahyar

Visualizing medical histories of patients with complex chronic diseases (e.g., discordant chronic comorbidities (DCCs)) is a challenge for patients, their healthcare providers, and their support network. DCCs are health conditions in which…

Human-Computer Interaction · Computer Science 2022-12-06 Sankarshan Dasgupta , Tom Ongwere

Brain-related diseases are more sensitive than other diseases due to several factors, including the complexity of surgical procedures, high costs, and other challenges. Alzheimer's disease is a common brain disorder that causes memory loss…

Image and Video Processing · Electrical Eng. & Systems 2024-03-11 Maleka Khatun , Md Manowarul Islam , Habibur Rahman Rifat , Md. Shamim Bin Shahid , Md. Alamin Talukder , Md Ashraf Uddin