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We show we can control an epidemic reaction-diffusion on a directed, and heterogeneous, network by redirecting the flows, thanks to the optimisation of well-designed loss functions, in particular the basic reproduction number of the model.…

Dynamical Systems · Mathematics 2022-02-07 Pierre-Yves Massé , Quentin Laborde , Maria Cherifa , Jules Olayé , Laurent Oudre

For preventing the spread of epidemics such as the coronavirus disease COVID-19, social distancing and the isolation of infected persons are crucial. However, existing reaction-diffusion equations for epidemic spreading are incapable of…

Populations and Evolution · Quantitative Biology 2020-11-18 Michael te Vrugt , Jens Bickmann , Raphael Wittkowski

The aim of the paper is to describe a model of the development of the Covid-19 contamination of the population of a country or a region. For this purpose a special branching process with two types of individuals is considered. This model is…

Methodology · Statistics 2020-04-03 Nikolay M. Yanev , Vessela K. Stoimenova , Dimitar V. Atanasov

We propose a novel testing and containment strategy in order to contain the spread of SARS-CoV2 while permitting large parts of the population to resume social and economic activity. Our approach recognises the fact that testing capacities…

Populations and Evolution · Quantitative Biology 2020-04-29 Jakob Jonnerby , Philip Lazos , Edwin Lock , Francisco Marmolejo-Cossío , C. Bronk Ramsey , Meghana Shukla , Divya Sridhar

We consider the control of the COVID-19 pandemic through a standard SIR compartmental model. This control is induced by the aggregation of individuals' decisions to limit their social interactions: when the epidemic is ongoing, an…

Physics and Society · Physics 2020-06-22 Romuald Elie , Emma Hubert , Gabriel Turinici

We consider a model for an epidemic in a population that occupies geographically distinct locations. The disease is spread within subpopulations by contacts between infective and susceptible individuals, and is spread between subpopulations…

Probability · Mathematics 2016-02-15 R. McVinish , P. K. Pollett , A. Shausan

This paper introduces a new optimal control model to describe and control the dynamics of infectious diseases. In the present model, the average time of isolation (i.e. hospitalization) of infectious population is the main time-dependent…

Optimization and Control · Mathematics 2015-05-06 Robin J. Evans , Musa Mammadov

During an epidemic outbreak, decision makers crucially need accurate and robust tools to monitor the pathogen propagation. The effective reproduction number, defined as the expected number of secondary infections stemming from one…

Signal Processing · Electrical Eng. & Systems 2026-01-14 Etienne Lasalle , Barbara Pascal

We demonstrate that the epidemic renormalisation group approach to pandemics provides an effective and simple way to investigate the dynamics of disease transmission and spreading across different regions of the world. The framework also…

Physics and Society · Physics 2020-05-12 Giacomo Cacciapaglia , Francesco Sannino

Breaking a complex bio-social phenomenon (epidemic) into its components, considering the processes that determine its dynamics, formalizing the accepted hypotheses in mathematical equations, selecting appropriate experimental and…

Physics and Society · Physics 2020-06-16 A. V. Sokolov , L. A. Sokolova

Policymakers commonly employ non-pharmaceutical interventions to manage the scale and severity of pandemics. Of non-pharmaceutical interventions, social distancing policies -- designed to reduce person-to-person pathogenic spread -- have…

Physics and Society · Physics 2021-03-23 Demetris Avraam , Nick Obradovich , Niccoló Pescetelli , Manuel Cebrian , Alex Rutherford

Epidemic spreading can be suppressed by the introduction of containment measures such as social distancing and lock downs. Yet, when such measures are relaxed, new epidemic waves and infection cycles may occur. Here we explore this issue in…

Physics and Society · Physics 2020-12-07 Fabio Caccioli , Daniele De Martino

Motivated by the issue of COVID-19 mitigation, in this work we tackle the general problem of optimally controlling an epidemic outbreak of a communicable disease structured by time since exposure, by the aid of two types of control…

Populations and Evolution · Quantitative Biology 2024-05-13 Alberto d'Onofrio , Mimmo Iannelli , Piero Manfredi , Gabriela Marinoschi

High impact epidemics constitute one of the largest threats humanity is facing in the 21st century. Testing, contact tracing and quarantining are critical in slowing down epidemic dynamics, but may prove insufficient for highly contagious…

Populations and Evolution · Quantitative Biology 2021-06-09 Davide Scarselli , Nazmi Burak Budanur , Marc Timme , Björn Hof

The outbreak of an infectious disease in a human population can lead to individuals responding with preventive measures in an attempt to avoid getting infected. This leads to changes in contact patterns. However, as we show in this paper,…

Populations and Evolution · Quantitative Biology 2018-05-15 Ka Yin Leung , Frank Ball , David Sirl , Tom Britton

We consider the SEIRS compartment epidemiology model suitable for predicting the evolution of the COVID-19 pandemy in the extreme limiting case of no acquired immunity. The disease-free and endemic fixed points are found and their stability…

Populations and Evolution · Quantitative Biology 2020-12-15 J. M. Ilnytskyi

The novel coronavirus SARS-CoV-2 and resulting COVID-19 disease have had an unprecedented spread and continue to cause an increasing number of fatalities worldwide. While vaccines are still under development, social distancing, extensive…

Populations and Evolution · Quantitative Biology 2020-07-02 Calvin Tsay , Fernando Lejarza , Mark A. Stadtherr , Michael Baldea

During the early months of the current COVID-19 pandemic, social-distancing measures effectively slowed disease transmission in many countries in Europe and Asia, but the same benefits have not been observed in some developing countries…

In this paper, we build a mathematical model for the dynamics of COVID-19 to assess the impact of placing healthy individuals in quarantine and isolating infected ones on the number of hospitalization and intensive care unit cases. The…

Populations and Evolution · Quantitative Biology 2023-05-04 Maryam Al-Yahyai , Fatma Al-Musalhi , Nasser Al-Salti , Ibrahim Elmojtaba

The spread of COVID-19 makes it essential to investigate its prevalence. In such investigation research, as far as we know, the widely-used sampling methods didn't use the information sufficiently about the numbers of the previously…

Applications · Statistics 2022-01-04 Ze Liu , Siyu Yi , Jianghu , Dong , Min-Qian Liu , Yongdao Zhou
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