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Deep neural networks have received considerable attention in clinical imaging, particularly with respect to the reduction of radiation risk. Lowering the radiation dose by reducing the photon flux inevitably results in the degradation of…

Image and Video Processing · Electrical Eng. & Systems 2021-09-14 Khalid L. Alsamadony , Ertugrul U. Yildirim , Guenther Glatz , Umair bin Waheed , Sherif M. Hanafy

Due to the potential risk of inducing cancers, radiation dose of X-ray CT should be reduced for routine patient scanning. However, in low-dose X-ray CT, severe artifacts usually occur due to photon starvation, beamhardening, etc, which…

Computer Vision and Pattern Recognition · Computer Science 2018-02-07 Eunhee Kang , Junhong Min , Jong Chul Ye

Background: Dual-energy CT (DECT) and material decomposition play vital roles in quantitative medical imaging. However, the decomposition process may suffer from significant noise amplification, leading to severely degraded image…

Image denoising is a prerequisite for downstream tasks in many fields. Low-dose and photon-counting computed tomography (CT) denoising can optimize diagnostic performance at minimized radiation dose. Supervised deep denoising methods are…

Machine Learning · Computer Science 2022-01-06 Chuang Niu , Mengzhou Li , Fenglei Fan , Weiwen Wu , Xiaodong Guo , Qing Lyu , Ge Wang

Deep learning has achieved notable performance in the denoising task of low-quality medical images and the detection task of lesions, respectively. However, existing low-quality medical image denoising approaches are disconnected from the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Kecheng Chen , Kun Long , Yazhou Ren , Jiayu Sun , Xiaorong Pu

Low-Dose Computed Tomography (LDCT) technique, which reduces the radiation harm to human bodies, is now attracting increasing interest in the medical imaging field. As the image quality is degraded by low dose radiation, LDCT exams require…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Liutao Yang , Zhongnian Li , Rongjun Ge , Junyong Zhao , Haipeng Si , Daoqiang Zhang

Cross-dose denoising for low-dose positron emission tomography (LDPET) has been proposed to address the limited generalization of models trained at a single noise level. However, neural networks trained on a specific dose level often fail…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Yichao Liu , Zongru Shao , Yueyang Teng , Junwen Guo

Low-Dose computer tomography (LDCT) is an ideal alternative to reduce radiation risk in clinical applications. Although supervised-deep-learning-based reconstruction methods have demonstrated superior performance compared to conventional…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Feng Wang , Renfang Wang , Hong Qiu

Computed tomography is widely used as an imaging tool to visualize three-dimensional structures with expressive bone-soft tissue contrast. However, CT resolution and radiation dose are tightly entangled, highlighting the importance of…

Image denoising of low-dose computed tomography (LDCT) is an important problem for clinical diagnosis with reduced radiation exposure. Previous methods are mostly trained with pairs of synthetic or misaligned LDCT and normal-dose CT (NDCT)…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Junhao Long , Fengwei Yang , Juncheng Yan , Baoping Zhang , Chao Jin , Jian Yang , Changliang Zou , Jun Xu

Since 2016, deep learning (DL) has advanced tomographic imaging with remarkable successes, especially in low-dose computed tomography (LDCT) imaging. Despite being driven by big data, the LDCT denoising and pure end-to-end reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2023-03-28 Wenjun Xia , Hongming Shan , Ge Wang , Yi Zhang

Most of the Deep Neural Networks (DNNs) based CT image denoising literature shows that DNNs outperform traditional iterative methods in terms of metrics such as the RMSE, the PSNR and the SSIM. In many instances, using the same metrics, the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-19 Prabhat KC , Rongping Zeng , M. Mehdi Farhangi , Kyle J. Myers

Low-dose CT images are essential for reducing radiation exposure in cancer screening, pediatric imaging, and longitudinal monitoring protocols, but their quality is often degraded by noise from low-dose acquisition, patient motion, or…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Jitindra Fartiyal , Pedro Freire , Sergei K. Turitsyn , Sergei G. Solovski

Low-dose CT has been a key diagnostic imaging modality to reduce the potential risk of radiation overdose to patient health. Despite recent advances, CNN-based approaches typically apply filters in a spatially invariant way and adopt…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Lu Xu , Yuwei Zhang , Ying Liu , Daoye Wang , Mu Zhou , Jimmy Ren , Jingwei Wei , Zhaoxiang Ye

A deep convolutional neural network has been developed to denoise atomic-resolution TEM image datasets of nanoparticles acquired using direct electron counting detectors, for applications where the image signal is severely limited by shot…

Reducing the radiation exposure for patients in Total-body CT scans has attracted extensive attention in the medical imaging community. Given the fact that low radiation dose may result in increased noise and artifacts, which greatly…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Minghan Fu , Yanhua Duan , Zhaoping Cheng , Wenjian Qin , Ying Wang , Dong Liang , Zhanli Hu

Sparse-view computed tomography (CT) can be used to reduce radiation dose greatly but is suffers from severe image artifacts. Recently, the deep learning based method for sparse-view CT reconstruction has attracted a major attention.…

Image and Video Processing · Electrical Eng. & Systems 2022-11-21 Wenjun Xia , Wenxiang Cong , Ge Wang

Deep learning (DL) has arguably emerged as the method of choice for the detection and segmentation of biological structures in microscopy images. However, DL typically needs copious amounts of annotated training data that is for biomedical…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Mangal Prakash , Tim-Oliver Buchholz , Manan Lalit , Pavel Tomancak , Florian Jug , Alexander Krull

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

Computed tomography (CT) is a popular medical imaging modality in clinical applications. At the same time, the x-ray radiation dose associated with CT scans raises public concerns due to its potential risks to the patients. Over the past…

Computer Vision and Pattern Recognition · Computer Science 2018-08-13 Chenyu You , Qingsong Yang , Hongming Shan , Lars Gjesteby , Guang Li , Shenghong Ju , Zhuiyang Zhang , Zhen Zhao , Yi Zhang , Wenxiang Cong , Ge Wang