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Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further…

The high complexity of deep learning models is associated with the difficulty of explaining what evidence they recognize as correlating with specific disease labels. This information is critical for building trust in models and finding…

Image and Video Processing · Electrical Eng. & Systems 2023-04-21 Ricardo Bigolin Lanfredi , Joyce D. Schroeder , Clement Vachet , Tolga Tasdizen

Understanding brain dynamics is important for neuroscience and mental health. Functional magnetic resonance imaging (fMRI) enables the measurement of neural activities through blood-oxygen-level-dependent (BOLD) signals, which represent…

Neurons and Cognition · Quantitative Biology 2025-06-16 Yifei Sun , Daniel Chahine , Qinghao Wen , Tianming Liu , Xiang Li , Yixuan Yuan , Fernando Calamante , Jinglei Lv

Age is an important variable to describe the expected brain's anatomy status across the normal aging trajectory. The deviation from that normative aging trajectory may provide some insights into neurological diseases. In neuroimaging,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-14 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

We describe a diffeomorphic registration algorithm that allows groups of images to be accurately aligned to a common space, which we intend to incorporate into the SPM software. The idea is to perform inference in a probabilistic graphical…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Mikael Brudfors , Yaël Balbastre , Guillaume Flandin , Parashkev Nachev , John Ashburner

Brain structural MRI has been widely used to assess the future progression of cognitive impairment (CI). Previous learning-based studies usually suffer from the issue of small-sized labeled training data, while there exist a huge amount of…

Image and Video Processing · Electrical Eng. & Systems 2023-06-27 Lintao Zhang , Jinjian Wu , Lihong Wang , Li Wang , David C. Steffens , Shijun Qiu , Guy G. Potter , Mingxia Liu

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

Age is an essential factor in modern diagnostic procedures. However, assessment of the true biological age (BA) remains a daunting task due to the lack of reference ground-truth labels. Current BA estimation approaches are either restricted…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Karim Armanious , Sherif Abdulatif , Wenbin Shi , Tobias Hepp , Sergios Gatidis , Bin Yang

Deep learning builds the foundation for many medical image analysis tasks where neuralnetworks are often designed to have a large receptive field to incorporate long spatialdependencies. Recent work has shown that large receptive fields are…

Image and Video Processing · Electrical Eng. & Systems 2019-07-27 Nick Pawlowski , Ben Glocker

Deep learning is leading to major advances in the realm of brain decoding from functional Magnetic Resonance Imaging (fMRI). However, the large inter-subject variability in brain characteristics has limited most studies to train models on…

Machine Learning · Computer Science 2023-12-12 Alexis Thual , Yohann Benchetrit , Felix Geilert , Jérémy Rapin , Iurii Makarov , Hubert Banville , Jean-Rémi King

Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep Learning providing…

We present Neural Shape Deformation Priors, a novel method for shape manipulation that predicts mesh deformations of non-rigid objects from user-provided handle movements. State-of-the-art methods cast this problem as an optimization task,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-02 Jiapeng Tang , Lev Markhasin , Bi Wang , Justus Thies , Matthias Nießner

Simultaneous modeling of the spatio-temporal variation patterns of brain functional network from 4D fMRI data has been an important yet challenging problem for the field of cognitive neuroscience and medical image analysis. Inspired by the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-24 Yu Zhao , Xiang Li , Wei Zhang , Shijie Zhao , Milad Makkie , Mo Zhang , Quanzheng Li , Tianming Liu

Multi-modal biological, imaging, and neuropsychological markers have demonstrated promising performance for distinguishing Alzheimer's disease (AD) patients from cognitively normal elders. However, it remains difficult to early predict when…

Computer Vision and Pattern Recognition · Computer Science 2019-01-08 Hongming Li , Yong Fan

Neurodegeneration, characterized by the progressive loss of neuronal structure or function, is commonly assessed in clinical practice through reductions in cortical thickness or brain volume, as visualized by structural MRI. While…

Signal Processing · Electrical Eng. & Systems 2025-10-15 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

Exploiting the wealth of imaging and non-imaging information for disease prediction tasks requires models capable of representing, at the same time, individual features as well as data associations between subjects from potentially large…

Neurons can display highly variable dynamics. While such variability presumably supports the wide range of behaviors generated by the organism, their gene expressions are relatively stable in the adult brain. This suggests that neuronal…

Neurons and Cognition · Quantitative Biology 2023-11-07 Lu Mi , Trung Le , Tianxing He , Eli Shlizerman , Uygar Sümbül

Smart systems that can accurately diagnose patients with mental disorders and identify effective treatments based on brain functional imaging data are of great applicability and are gaining much attention. Most previous machine learning…

Computer Vision and Pattern Recognition · Computer Science 2017-12-05 Jumana Dakka , Pouya Bashivan , Mina Gheiratmand , Irina Rish , Shantenu Jha , Russell Greiner

Demographic attributes such as age, sex, and race can be predicted from medical images, raising concerns about bias in clinical AI systems. In brain MRI, this signal may arise from anatomical variation, acquisition-dependent contrast…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Mehmet Yigit Avci , Akshit Achara , Andrew King , Jorge Cardoso