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A U-Net based deep learning architecture is designed to segment brain tumors as they appear on various MRI modalities. Special emphasis is lent to the non-enhancing tumor compartment. The latter has not been considered anymore in recent…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 T. Schaffer , A. Brawanski , S. Wein , A. M. Tomé , E. W. Lang

Pathologic analysis of surgical excision specimens for breast carcinoma is important to evaluate the completeness of surgical excision and has implications for future treatment. This analysis is performed manually by pathologists reviewing…

Image and Video Processing · Electrical Eng. & Systems 2021-01-22 David Joon Ho , Dig V. K. Yarlagadda , Timothy M. D'Alfonso , Matthew G. Hanna , Anne Grabenstetter , Peter Ntiamoah , Edi Brogi , Lee K. Tan , Thomas J. Fuchs

Deep learning techniques have successfully been employed in numerous computer vision tasks including image segmentation. The techniques have also been applied to medical image segmentation, one of the most critical tasks in computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2020-06-30 Titinunt Kitrungrotsakul , Iwamoto Yutaro , Lanfen Lin , Ruofeng Tong , Jingsong Li , Yen-Wei Chen

$\bf{Purpose:}$ The goal of this study was (i) to use artificial intelligence to automate the traditionally labor-intensive process of manual segmentation of tumor regions in pathology slides performed by a pathologist and (ii) to validate…

Medical image segmentation, particularly tumor segmentation, is a critical task in medical imaging, with U-Net being a widely adopted convolutional neural network (CNN) architecture for this purpose. However, U-Net's high computational and…

Image and Video Processing · Electrical Eng. & Systems 2025-03-13 Christiaan Boerkamp , Akhil John Thomas

Cancer is an abnormal growth with potential to invade locally and metastasize to distant organs. Accurate auto-segmentation of the tumor and surrounding normal tissues is required for radiotherapy treatment plan optimization. Recent…

Image and Video Processing · Electrical Eng. & Systems 2025-07-31 Syed Haider Ali , Asrar Ahmad , Muhammad Ali , Asifullah Khan , Nadeem Shaukat

Deep learning has made a breakthrough in medical image segmentation in recent years due to its ability to extract high-level features without the need for prior knowledge. In this context, U-Net is one of the most advanced medical image…

Image and Video Processing · Electrical Eng. & Systems 2022-11-07 Prithul Sarker , Sushmita Sarker , George Bebis , Alireza Tavakkoli

There is large consent that successful training of deep networks requires many thousand annotated training samples. In this paper, we present a network and training strategy that relies on the strong use of data augmentation to use the…

Computer Vision and Pattern Recognition · Computer Science 2015-05-19 Olaf Ronneberger , Philipp Fischer , Thomas Brox

Purpose: Manual medical image segmentation is an exhausting and time-consuming task along with high inter-observer variability. In this study, our objective is to improve the multi-resolution image segmentation performance of U-Net…

Image and Video Processing · Electrical Eng. & Systems 2020-07-20 Simindokht Jahangard , Mohammad Hossein Zangooei , Maysam Shahedi

Semantic segmentation is an import task in the medical field to identify the exact extent and orientation of significant structures like organs and pathology. Deep neural networks can perform this task well by leveraging the information…

Computer Vision and Pattern Recognition · Computer Science 2019-09-18 Abhijeet Parida , Arianne Tran , Nassir Navab , Shadi Albarqouni

Models based on U-like structures have improved the performance of medical image segmentation. However, the single-layer decoder structure of U-Net is too "thin" to exploit enough information, resulting in large semantic differences between…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Haoyuan Chen , Yufei Han , Pin Xu , Yanyi Li , Kuan Li , Jianping Yin

Various deep learning methods have been proposed to segment breast lesion from ultrasound images. However, similar intensity distributions, variable tumor morphology and blurred boundaries present challenges for breast lesions segmentation,…

Image and Video Processing · Electrical Eng. & Systems 2024-01-23 Gongping Chen , Yu Dai , Jianxun Zhang , Moi Hoon Yap

Medical image segmentation is an important step in medical image analysis, especially as a crucial prerequisite for efficient disease diagnosis and treatment. The use of deep learning for image segmentation has become a prevalent trend. The…

Image and Video Processing · Electrical Eng. & Systems 2023-08-11 Wenjian Yao , Jiajun Bai , Wei Liao , Yuheng Chen , Mengjuan Liu , Yao Xie

Mammography images are widely used to detect non-palpable breast lesions or nodules, preventing cancer and providing the opportunity to plan interventions when necessary. The identification of some structures of interest is essential to…

Image and Video Processing · Electrical Eng. & Systems 2023-07-21 Cesar A. Sierra-Franco , Jan Hurtado , Victor de A. Thomaz , Leonardo C. da Cruz , Santiago V. Silva , Alberto B. Raposo

The segmentation of brain tumors in multimodal MRIs is one of the most challenging tasks in medical image analysis. The recent state of the art algorithms solving this task is based on machine learning approaches and deep learning in…

Image and Video Processing · Electrical Eng. & Systems 2020-02-11 Dmitrii Lachinov , Elena Shipunova , Vadim Turlapov

Methods to detect malignant lesions from screening mammograms are usually trained with fully annotated datasets, where images are labelled with the localisation and classification of cancerous lesions. However, real-world screening…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Yuanhong Chen , Yuyuan Liu , Chong Wang , Michael Elliott , Chun Fung Kwok , Carlos Pena-Solorzano , Yu Tian , Fengbei Liu , Helen Frazer , Davis J. McCarthy , Gustavo Carneiro

The integration of machine learning in magnetic resonance imaging (MRI), specifically in neuroimaging, is proving to be incredibly effective, leading to better diagnostic accuracy, accelerated image analysis, and data-driven insights, which…

In this paper, we propose a new pre-training scheme for U-net based image segmentation. We first train the encoding arm as a localization network to predict the center of the target, before extending it into a U-net architecture for…

The task of medical image segmentation presents unique challenges, necessitating both localized and holistic semantic understanding to accurately delineate areas of interest, such as critical tissues or aberrant features. This complexity is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Pranav Singh , Luoyao Chen , Mei Chen , Jinqian Pan , Raviteja Chukkapalli , Shravan Chaudhari , Jacopo Cirrone

Generalization capabilities of learning-based medical image segmentation across domains are currently limited by the performance degradation caused by the domain shift, particularly for ultrasound (US) imaging. The quality of US images…

Image and Video Processing · Electrical Eng. & Systems 2024-02-07 Yuan Bi , Zhongliang Jiang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab