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In this work, we propose three explainable deep learning architectures to automatically detect patients with Alzheimer`s disease based on their language abilities. The architectures use: (1) only the part-of-speech features; (2) only…
Introduction- This paper mainly describes a way to detect with high accuracy patients with early-stage Alzheimer's disease (ES-AD) versus healthy control (HC) subjects, from datasets built with handwriting and drawing task records. Method-…
As the aging of society continues to accelerate, Alzheimer's Disease (AD) has received more and more attention from not only medical but also other fields, such as computer science, over the past decade. Since speech is considered one of…
The current clinical diagnosis framework of Alzheimer's disease (AD) involves multiple modalities acquired from multiple diagnosis stages, each with distinct usage and cost. Previous AD diagnosis research has predominantly focused on how to…
Depression is one of the most prevalent mental health disorders globally. In recent years, multi-modal data, such as speech, video, and transcripts, has been increasingly used to develop AI-assisted depression assessment systems. Large…
Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease. Early and precise diagnosis of AD is crucial for timely intervention and treatment planning to alleviate the progressive neurodegeneration. However, most…
Speech contains both acoustic and linguistic patterns that reflect cognitive decline, and therefore models describing only one domain cannot fully capture such complexity. This study investigates how early fusion (EF) of speech and its…
Background: Dementia, marked by cognitive decline, is a global health challenge. Alzheimer's disease (AD), the leading type, accounts for ~70% of cases. Electroencephalography (EEG) measures show promise in identifying AD risk, but…
As the global burden of Alzheimer's disease (AD) continues to grow, early and accurate detection has become increasingly critical, especially in regions with limited access to advanced diagnostic tools. We propose BRAINS (Biomedical…
Dementia, a progressive neurodegenerative disorder, affects memory, reasoning, and daily functioning, creating challenges for individuals and healthcare systems. Early detection is crucial for timely interventions that may slow disease…
Depression is a critical concern in global mental health, prompting extensive research into AI-based detection methods. Among various AI technologies, Large Language Models (LLMs) stand out for their versatility in mental healthcare…
Dementia encompasses a group of syndromes that impair cognitive functions such as memory, reasoning, and the ability to perform daily activities. As populations globally age, over 10 million new dementia diagnoses are reported annually.…
Alzheimer's is a brain disease that gets worse over time and affects memory, thinking, and behavior. Alzheimer's disease (AD) can be treated and managed if it is diagnosed early, which can slow the progression of symptoms and improve…
Audio-visual speech recognition (AVSR) system is thought to be one of the most promising solutions for robust speech recognition, especially in noisy environment. In this paper, we propose a novel multimodal attention based method for…
Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…
We describe a new method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on multidimensional classification of hippocampal shape features. This…
Early diagnosis of Alzheimer's Disease (AD) is crucial for delaying its progression. While AI-based speech detection is non-invasive and cost-effective, it faces a critical data efficiency dilemma due to medical data scarcity and privacy…
Over half of US adults with Alzheimer disease and related dementias remain undiagnosed, and speech-based screening offers a scalable detection approach. We compared large language model adaptation strategies for dementia detection using the…
Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. In this disease, there is a critical phase, mild cognitive impairment, that is really…
Alzheimer's disease and related dementias (ADRD) affect one in five adults over 60, yet more than half of individuals with cognitive decline remain undiagnosed. Speech-based assessments show promise for early detection, as phonetic motor…