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We study the target control of asynchronous Boolean networks, to identify efficacious interventions that can drive the dynamics of a given Boolean network from any initial state to the desired target attractor. Based on the application…

Systems and Control · Electrical Eng. & Systems 2021-01-05 Cui Su , Jun Pang

This paper proposes the incremental Bayesian optimization algorithm (iBOA), which modifies standard BOA by removing the population of solutions and using incremental updates of the Bayesian network. iBOA is shown to be able to learn and…

Neural and Evolutionary Computing · Computer Science 2008-07-30 Martin Pelikan , Kumara Sastry , David E. Goldberg

We state an algorithm that, given an automata network and a block-sequential update schedule, produces an automata network of the same size or smaller with the same limit dynamics under the parallel update schedule. Then, we focus on the…

Discrete Mathematics · Computer Science 2023-04-27 Pacôme Perrotin , Sylvain Sené

Asymptotic behaviors are often of particular interest when analyzing Boolean networks that represent biological systems such as signal trans- duction or gene regulatory networks. Methods based on a generalization of the steady state notion,…

Dynamical Systems · Mathematics 2015-09-30 Hannes Klarner , Alexander Bockmayr , Heike Siebert

This review explains in a self-contained way the properties of random Boolean networks and their attractors, with a special focus on critical networks. Using small example networks, analytical calculations, phenomenological arguments, and…

Statistical Mechanics · Physics 2008-11-14 Barbara Drossel

Boolean networks have been used in a variety of settings, as models for general complex systems as well as models of specific systems in diverse fields, such as biology, engineering, and computer science. Traditionally, their properties as…

Dynamical Systems · Mathematics 2024-02-02 Matthew Wheeler , Claus Kadelka , Alan Veliz-Cuba , David Murrugarra , Reinhard Laubenbacher

The understanding of Boolean automata networks dynamics takes an important place in various domains of computer science such as computability, complexity and discrete dynamical systems. In this paper, we make a step further in this…

Formal Languages and Automata Theory · Computer Science 2014-02-19 Tarek Melliti , Mathilde Noual , Damien Regnault , Sylvain Sené , Jérémy Sobieraj

The number of parameters in large-scale language models based on transformers is gradually increasing, and the scale of computing clusters is also growing. The technology of quickly mobilizing large amounts of computing resources for…

Artificial Intelligence · Computer Science 2025-01-03 Zongbiao Li , Xiezhao Li , Yinghao Cui , Yijun Chen , Zhixuan Gu , Yuxuan Liu , Wenbo Zhu , Fei Jia , Ke Liu , Qifeng Li , Junyao Zhan , Jiangtao Zhou , Chenxi Zhang , Qike Liu

Boolean networks are a general model of interacting entities, with applications to biological phenomena such as gene regulation. Attractors play a central role, and the schedule of entities update is a priori unknown. This article presents…

Discrete Mathematics · Computer Science 2020-01-22 Florian Bridoux , Caroline Gaze-Maillot , Kévin Perrot , Sylvain Sené

We extend a recently introduced class of exactly solvable models for recurrent neural networks with competition between 1D nearest neighbour and infinite range information processing. We increase the potential for further frustration and…

Disordered Systems and Neural Networks · Physics 2009-10-31 N. S. Skantzos , A. C. C. Coolen

System performance for networks composed of interconnected subsystems can be increased if the traditionally separated subsystems are jointly optimized. Recently, parallel and distributed optimization methods have emerged as a powerful tool…

Optimization and Control · Mathematics 2013-02-14 Ion Necoara , Valentin Nedelcu , Ioan Dumitrache

We present and discuss the results of an experimental analysis in the design of Boolean networks by means of genetic algorithms. A population of networks is evolved with the aim of finding a network such that the attractor it reaches is of…

Neural and Evolutionary Computing · Computer Science 2011-02-01 Andrea Roli , Cristian Arcaroli , Marco Lazzarini , Stefano Benedettini

We study the stable attractors of a class of continuous dynamical systems that may be idealized as networks of Boolean elements, with the goal of determining which Boolean attractors, if any, are good approximations of the attractors of…

Molecular Networks · Quantitative Biology 2009-11-13 Johannes Norrell , Björn Samuelsson , Joshua E. S. Socolar

Boolean automata networks (BANs) are a generalisation of Boolean cellular automata. In such, any theorem describing the way BANs compute information is a strong tool that can be applied to a wide range of models of computation. In this…

Discrete Mathematics · Computer Science 2018-04-10 Kévin Perrot , Pacôme Perrotin , Sylvain Sené

In this paper we study the dynamical behavior of Boolean networks with firing memory, namely Boolean networks whose vertices are updated synchronously depending on their proper Boolean local transition functions so that each vertex remains…

Discrete Mathematics · Computer Science 2022-04-25 Eric Goles , Fabiola Lobos , Gonzalo A. Ruz , Sylvain Sené

To model biological systems using networks, it is desirable to allow more than two levels of expression for the nodes and to allow the introduction of parameters. Various modeling and simulation methods addressing these needs using Boolean…

Molecular Networks · Quantitative Biology 2014-04-23 Yi Ming Zou

The Kauffman model describes a particularly simple class of random Boolean networks. Despite the simplicity of the model, it exhibits complex behavior and has been suggested as a model for real world network problems. We introduce a novel…

Disordered Systems and Neural Networks · Physics 2007-05-23 B. Samuelsson , C. Troein

The method of reconstruction of an attractor from a set of short time series ({\it clusters}) is proposed and discussed. This method is most useful for correlation dimension estimation of experimental data.

comp-gas · Physics 2016-08-31 A. A. Kipchatov , L. V. Krasichkov

In this paper we try to end the debate concerning the suitability of different updating schemes in random Boolean networks (RBNs). We quantify for the first time loose attractors in asyncrhonous RBNs, which allows us to analyze the…

Adaptation and Self-Organizing Systems · Physics 2011-11-10 Carlos Gershenson

We study the problem of computing a minimal subset of nodes of a given asynchronous Boolean network that need to be controlled to drive its dynamics from an initial steady state (or attractor) to a target steady state. Due to the phenomenon…

Systems and Control · Computer Science 2018-05-18 Soumya Paul , Cui Su , Jun Pang , Andrzej Mizera