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Separating and labeling each instance of a nucleus (instance-aware segmentation) is the key challenge in segmenting single cell nuclei on fluorescence microscopy images. Deep Neural Networks can learn the implicit transformation of a…

Computer Vision and Pattern Recognition · Computer Science 2021-08-11 Florian Kromp , Lukas Fischer , Eva Bozsaky , Inge Ambros , Wolfgang Doerr , Sabine Taschner-Mandl , Peter Ambros , Allan Hanbury

Instance segmentation of nuclei and glands in the histology images is an important step in computational pathology workflow for cancer diagnosis, treatment planning and survival analysis. With the advent of modern hardware, the recent…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Esha Sadia Nasir , Arshi Perviaz , Muhammad Moazam Fraz

Identify the cells' nuclei is the important point for most medical analyses. To assist doctors finding the accurate cell' nuclei location automatically is highly demanded in the clinical practice. Recently, fully convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Tianyang Zhang , Rui Ma

Nuclei segmentation is a fundamental prerequisite in the digital pathology workflow. The development of automated methods for nuclei segmentation enables quantitative analysis of the wide existence and large variances in nuclei morphometry…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yi Lin , Zeyu Wang , Dong Zhang , Kwang-Ting Cheng , Hao Chen

Deep learning based image segmentation has achieved the state-of-the-art performance in many medical applications such as lesion quantification, organ detection, etc. However, most of the methods rely on supervised learning, which require a…

Computer Vision and Pattern Recognition · Computer Science 2020-04-20 Ruizhe Li , Dorothee Auer , Christian Wagner , Xin Chen

3D instance segmentation methods often require fully-annotated dense labels for training, which are costly to obtain. In this paper, we present ClickSeg, a novel click-level weakly supervised 3D instance segmentation method that requires…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Leyao Liu , Tao Kong , Minzhao Zhu , Jiashuo Fan , Lu Fang

Segmentation is one of the most important tasks in the medical imaging pipeline as it influences a number of image-based decisions. To be effective, fully supervised segmentation approaches require large amounts of manually annotated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Tyler Ward , Aaron Moseley , Abdullah-Al-Zubaer Imran

Recently, deep learning enabled the accurate segmentation of various diseases in medical imaging. These performances, however, typically demand large amounts of manual voxel annotations. This tedious process for volumetric data becomes more…

3D scene understanding, e.g., point cloud semantic and instance segmentation, often requires large-scale annotated training data, but clearly, point-wise labels are too tedious to prepare. While some recent methods propose to train a 3D…

Computer Vision and Pattern Recognition · Computer Science 2023-09-13 Zhengzhe Liu , Xiaojuan Qi , Chi-Wing Fu

Annotating videos with object segmentation masks typically involves a two stage procedure of drawing polygons per object instance for all the frames and then linking them through time. While simple, this is a very tedious, time consuming…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 Namdar Homayounfar , Justin Liang , Wei-Chiu Ma , Raquel Urtasun

Curating large-scale fully annotated datasets is expensive, laborious, and cumbersome, especially for medical images. Several methods have been proposed in the literature that make use of weak annotations in the form of scribbles. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Ke Zhang , Vishal M. Patel

Multi-class cell segmentation in high-resolution Giga-pixel whole slide images (WSI) is critical for various clinical applications. Training such an AI model typically requires labor-intensive pixel-wise manual annotation from experienced…

Segmentation in medical imaging is an essential and often preliminary task in the image processing chain, driving numerous efforts towards the design of robust segmentation algorithms. Supervised learning methods achieve excellent…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Pierre Rougé , Pierre-Henri Conze , Nicolas Passat , Odyssée Merveille

Accurate segmentation of tissue in histopathological images can be very beneficial for defining regions of interest (ROI) for streamline of diagnostic and prognostic tasks. Still, adapting to different domains is essential for…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Saul Fuster , Farbod Khoraminia , Trygve Eftestøl , Tahlita C. M. Zuiverloon , Kjersti Engan

Infrared Small Target Detection is a challenging task to separate small targets from infrared clutter background. Recently, deep learning paradigms have achieved promising results. However, these data-driven methods need plenty of manual…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Haoqing Li , Jinfu Yang , Yifei Xu , Runshi Wang

Cell image segmentation is usually implemented using fully supervised deep learning methods, which heavily rely on extensive annotated training data. Yet, due to the complexity of cell morphology and the requirement for specialized…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Yu Zhu , Qiang Yang , Li Xu

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Satoshi Kondo , Satoshi Kasai

Nuclei segmentation is the cornerstone task in histology image reading, shedding light on the underlying molecular patterns and leading to disease or cancer diagnosis. Yet, it is a laborious task that requires expertise from trained…

Image and Video Processing · Electrical Eng. & Systems 2025-11-10 Vasileios Magoulianitis , Catherine A. Alexander , Jiaxin Yang , C. -C. Jay Kuo

Due to the wide existence and large morphological variances of nuclei, accurate nuclei instance segmentation is still one of the most challenging tasks in computational pathology. The annotating of nuclei instances, requiring experienced…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Xinpeng Xie , Jiawei Chen , Yuexiang Li , Linlin Shen , Kai Ma , Yefeng Zheng

Cell and nucleus segmentation are fundamental tasks for quantitative bioimage analysis. Despite progress in recent years, biologists and other domain experts still require novel algorithms to handle increasingly large and complex real-world…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Thibaut Goldsborough , Ben Philps , Alan O'Callaghan , Fiona Inglis , Leo Leplat , Andrew Filby , Hakan Bilen , Peter Bankhead