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Background/Aims: Standard Automated Perimetry (SAP) is the gold standard to monitor visual field (VF) loss in glaucoma management, but is prone to intra-subject variability. We developed and validated a deep learning (DL) regression model…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Ruben Hemelings , Bart Elen , João Barbosa Breda , Erwin Bellon , Matthew B Blaschko , Patrick De Boever , Ingeborg Stalmans

Diabetic retinopathy (DR) is a severe complication of diabetes that can cause permanent blindness. Timely diagnosis and treatment of DR are critical to avoid total loss of vision. Manual diagnosis is time consuming and error-prone. In this…

Image and Video Processing · Electrical Eng. & Systems 2021-10-05 Ramya Bygari , Rachita Naik , Uday Kumar P

Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex morphological changes with the development and progression of glaucoma, their simultaneous isolation from optical coherence tomography (OCT) images…

Ultra-widefield (UWF) imaging is a promising modality that captures a larger retinal field of view compared to traditional fundus photography. Previous studies showed that deep learning (DL) models are effective for detecting retinal…

Image and Video Processing · Electrical Eng. & Systems 2022-03-14 Justin Engelmann , Alice D. McTrusty , Ian J. C. MacCormick , Emma Pead , Amos Storkey , Miguel O. Bernabeu

Purpose To develop a computer based method for the automated assessment of image quality in the context of diabetic retinopathy (DR) to guide the photographer. Methods A deep learning framework was trained to grade the images automatically.…

Computer Vision and Pattern Recognition · Computer Science 2017-03-08 Sajib Kumar Saha , Basura Fernando , Jorge Cuadros , Di Xiao , Yogesan Kanagasingam

Diabetic Retinopathy (DR) is a prominent cause of blindness in the world. The early treatment of DR can be conducted from detection of microaneurysms (MAs) which appears as reddish spots in retinal images. An automated microaneurysm…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Noushin Eftekheri , Mojtaba Masoudi , Hamidreza Pourreza , Kamaledin Ghiasi Shirazi , Ehsan Saeedi

This research paper addresses the critical challenge of diabetic retinopathy (DR), a severe complication of diabetes leading to potential blindness. The proposed methodology leverages transfer learning with convolutional neural networks…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Manoj S H , Arya A Bosale

Optic disc and cup segmentation plays a crucial role in automating the screening and diagnosis of optic glaucoma. While data-driven convolutional neural networks (CNNs) show promise in this area, the inherent ambiguity of segmenting objects…

Computer Vision and Pattern Recognition · Computer Science 2024-03-18 Tengjin Weng , Yang Shen , Zhidong Zhao , Zhiming Cheng , Shuai Wang

Purpose: To assess the utility of deep learning in the detection of geographic atrophy (GA) from color fundus photographs; secondary aim to explore potential utility in detecting central GA (CGA). Design: A deep learning model was developed…

Image and Video Processing · Electrical Eng. & Systems 2019-06-10 Tiarnan D. Keenan , Shazia Dharssi , Yifan Peng , Qingyu Chen , Elvira Agrón , Wai T. Wong , Zhiyong Lu , Emily Y. Chew

Glaucoma is one of the leading causes of irreversible blindness worldwide. Glaucoma prognosis is essential for identifying at-risk patients and enabling timely intervention to prevent blindness. Many existing approaches rely on historical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yiran Song , Yikai Zhang , Silvia Orengo-Nania , Nian Wang , Fenglong Ma , Rui Zhang , Yifan Peng , Mingquan Lin

According to multiple authoritative authorities, including the World Health Organization, vision-related impairments and disorders are becoming a significant issue. According to a recent report, one of the leading causes of irreversible…

Computer Vision and Pattern Recognition · Computer Science 2022-10-31 Dishant Padalia , Abhishek Mazumdar , Bharati Singh

The performance of diagnostic Computer-Aided Design (CAD) systems for retinal diseases depends on the quality of the retinal images being screened. Thus, many studies have been developed to evaluate and assess the quality of such retinal…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Saif Khalid , Hatem A. Rashwan , Saddam Abdulwahab , Mohamed Abdel-Nasser , Facundo Manuel Quiroga , Domenec Puig

This paper presents Deep Retinal Image Understanding (DRIU), a unified framework of retinal image analysis that provides both retinal vessel and optic disc segmentation. We make use of deep Convolutional Neural Networks (CNNs), which have…

Computer Vision and Pattern Recognition · Computer Science 2016-11-17 Kevis-Kokitsi Maninis , Jordi Pont-Tuset , Pablo Arbeláez , Luc Van Gool

This investigation reports on the results of convolutional neural networks developed for the recently introduced PathologicAL Myopia (PALM) dataset, which consists of 1200 fundus images. We propose a new Optic Nerve Head (ONH)-based…

Image and Video Processing · Electrical Eng. & Systems 2020-06-05 Ruben Hemelings , Bart Elen , Matthew B. Blaschko , Julie Jacob , Ingeborg Stalmans , Patrick De Boever

Retinal disease diagnosis is critical in preventing vision loss and reducing socioeconomic burdens. Globally, over 2.2 billion people are affected by some form of vision impairment, resulting in annual productivity losses estimated at $411…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Youssef Sabiri , Walid Houmaidi , Amine Abouaomar

Diabetic Retinopathy (DR) refers to a barrier that takes place in diabetes mellitus damaging the blood vessel network present in the retina. This may endanger the subjects' vision if they have diabetes. It can take some time to perform a DR…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 V. Banupriya , S. Anusuya

Purpose: This study introduces the first adaptation of RETFound for joint optic disc (OD) and optic cup (OC) segmentation. RETFound is a well-known foundation model developed for fundus camera and optical coherence tomography images, which…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Zhenyi Zhao , Muthu Rama Krishnan Mookiah , Emanuele Trucco

This paper presents a computationally efficient method for the detection of optic nerve head in both color fundus and fluorescein angiography images. It involves a combination of Radon transformation and multi-overlapping windows within an…

Medical Physics · Physics 2019-10-03 Reza Pourreza-Shahri , Meysam Tavakoli , Nasser Kehtarnavaz

For accurate glaucoma diagnosis and monitoring, reliable retinal layer segmentation in OCT images is essential. However, existing 2D segmentation methods often suffer from slice-to-slice inconsistencies due to the lack of contextual…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Hyunwoo Kim , Heesuk Kim , Wungrak Choi , Jae-Sang Hyun

Diabetic Retinopathy (DR) is a leading cause of vision loss globally. Yet despite its prevalence, the majority of affected people lack access to the specialized ophthalmologists and equipment required for assessing their condition. This can…

Computer Vision and Pattern Recognition · Computer Science 2021-10-22 Alexandros Papadopoulos , Fotis Topouzis , Anastasios Delopoulos