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We explore encoding brain symmetry into a neural network for a brain tumor segmentation task. A healthy human brain is symmetric at a high level of abstraction, and the high-level asymmetric parts are more likely to be tumor regions. Paying…

Computer Vision and Pattern Recognition · Computer Science 2017-11-20 Hejia Zhang , Xia Zhu , Theodore L. Willke

Accurate and reliable tumor segmentation is essential in medical imaging analysis for improving diagnosis, treatment planning, and monitoring. However, existing segmentation models often lack robust mechanisms for quantifying the…

Image and Video Processing · Electrical Eng. & Systems 2025-03-14 Seyed Sina Ziaee , Farhad Maleki , Katie Ovens

Image segmentation enables to extract quantitative measures from scans that can serve as imaging biomarkers for diseases. However, segmentation quality can vary substantially across scans, and therefore yield unfaithful estimates in the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 J. Senapati , A. Guha Roy , S. Pölsterl , D. Gutmann , S. Gatidis , C. Schlett , A. Peters , F. Bamberg , C. Wachinger

Brain tumor is deliberated as one of the severe health complications which lead to decrease in life expectancy of the individuals and is also considered as a prominent cause of mortality worldwide. Therefore, timely detection and prediction…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Tejashwini P S , Thriveni J , Venugopal K R

Past few years have witnessed the prevalence of deep learning in many application scenarios, among which is medical image processing. Diagnosis and treatment of brain tumors requires an accurate and reliable segmentation of brain tumors as…

Image and Video Processing · Electrical Eng. & Systems 2020-05-26 Feifan Wang , Runzhou Jiang , Liqin Zheng , Chun Meng , Bharat Biswal

Measuring uncertainties in the output of a deep learning method is useful in several ways, such as in assisting with interpretation of the outputs, helping build confidence with end users, and for improving the training and performance of…

Machine Learning · Computer Science 2022-09-20 Luke Whitbread , Mark Jenkinson

In this paper, we study the problem of uncertainty estimation and calibration for LLMs. We begin by formulating the uncertainty estimation problem, a relevant yet underexplored area in existing literature. We then propose a supervised…

Machine Learning · Computer Science 2024-10-24 Linyu Liu , Yu Pan , Xiaocheng Li , Guanting Chen

Automated medical image segmentation inherently involves a certain degree of uncertainty. One key factor contributing to this uncertainty is the ambiguity that can arise in determining the boundaries of a target region of interest,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Qingqiao Hu , Hao Wang , Jing Luo , Yunhao Luo , Zhiheng Zhangg , Jan S. Kirschke , Benedikt Wiestler , Bjoern Menze , Jianguo Zhang , Hongwei Bran Li

Accurate medical image segmentation is crucial for diagnosis and analysis. However, the models without calibrated uncertainty estimates might lead to errors in downstream analysis and exhibit low levels of robustness. Estimating the…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Yanwu Yang , Xutao Guo , Yiwei Pan , Pengcheng Shi , Haiyan Lv , Ting Ma

Survival models are used in various fields, such as the development of cancer treatment protocols. Although many statistical and machine learning models have been proposed to achieve accurate survival predictions, little attention has been…

Machine Learning · Computer Science 2020-03-26 Hrushikesh Loya , Pranav Poduval , Deepak Anand , Neeraj Kumar , Amit Sethi

Segmentation tasks in medical imaging are inherently ambiguous: the boundary of a target structure is oftentimes unclear due to image quality and biological factors. As such, predicted segmentations from deep learning algorithms are…

Image and Video Processing · Electrical Eng. & Systems 2019-11-18 Katharina Hoebel , Ken Chang , Jay Patel , Praveer Singh , Jayashree Kalpathy-Cramer

Cancer of the brain is deadly and requires careful surgical segmentation. The brain tumors were segmented using U-Net using a Convolutional Neural Network (CNN). When looking for overlaps of necrotic, edematous, growing, and healthy tissue,…

Image and Video Processing · Electrical Eng. & Systems 2023-01-18 MD Abdullah Al Nasim , Abdullah Al Munem , Maksuda Islam , Md Aminul Haque Palash , MD. Mahim Anjum Haque , Faisal Muhammad Shah

Accurate segmentation of brain tumors plays a key role in the diagnosis and treatment of brain tumor diseases. It serves as a critical technology for quantifying tumors and extracting their features. With the increasing application of deep…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Longfeng Shen , Yanqi Hou , Jiacong Chen , Liangjin Diao , Yaxi Duan

Accurate brain tumor segmentation from MRI scans is critical for diagnosis and treatment planning. Despite the strong performance of recent deep learning approaches, two fundamental limitations remain: (1) the lack of reliable uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Bahram Mohammadi , Yanqiu Wu , Vu Minh Hieu Phan , Sam White , Minh-Son To , Jian Yang , Michael Sheng , Yang Song , Yuankai Qi

Ratio-based biomarkers (RBBs), such as the proportion of necrotic tissue within a tumor, are widely used in clinical practice to support diagnosis, prognosis, and treatment planning. These biomarkers are typically estimated from…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Jiameng Li , Teodora Popordanoska , Aleksei Tiulpin , Sebastian G. Gruber , Frederik Maes , Matthew B. Blaschko

Automatic segmentation is essential for the brain tumor diagnosis, disease prognosis, and follow-up therapy of patients with gliomas. Still, accurate detection of gliomas and their sub-regions in multimodal MRI is very challenging due to…

Image and Video Processing · Electrical Eng. & Systems 2022-12-20 Ramy A. Zeineldin , Mohamed E. Karar , Oliver Burgert , Franziska Mathis-Ullrich

Cognitive diagnosis models have been widely used in different areas, especially intelligent education, to measure users' proficiency levels on knowledge concepts, based on which users can get personalized instructions. As the measurement is…

Computers and Society · Computer Science 2024-03-25 Fei Wang , Qi Liu , Enhong Chen , Chuanren Liu , Zhenya Huang , Jinze Wu , Shijin Wang

The accurate automatic segmentation of gliomas and its intra-tumoral structures is important not only for treatment planning but also for follow-up evaluations. Several methods based on 2D and 3D Deep Neural Networks (DNN) have been…

Image and Video Processing · Electrical Eng. & Systems 2020-01-28 Parth Natekar , Avinash Kori , Ganapathy Krishnamurthi

We introduce inherent measures for effective quality control of brain segmentation based on a Bayesian fully convolutional neural network, using model uncertainty. Monte Carlo samples from the posterior distribution are efficiently…

Computer Vision and Pattern Recognition · Computer Science 2018-06-11 Abhijit Guha Roy , Sailesh Conjeti , Nassir Navab , Christian Wachinger

The BraTS dataset contains a mixture of high-grade and low-grade gliomas, which have a rather different appearance: previous studies have shown that performance can be improved by separated training on low-grade gliomas (LGGs) and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-14 Richard McKinley , Micheal Rebsamen , Katrin Daetwyler , Raphael Meier , Piotr Radojewski , Roland Wiest