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Stochastic simulation is a widely used method for estimating quantities in models of chemical reaction networks where uncertainty plays a crucial role. However, reducing the statistical uncertainty of the corresponding estimators requires…

Quantitative Methods · Quantitative Biology 2019-06-13 Michael Backenköhler , Luca Bortolussi , Verena Wolf

In this paper we study simulation-based methods for estimating gradients in stochastic networks. We derive a new method of calculating weak derivative estimator using importance sampling transform, and our method has less computational cost…

Methodology · Statistics 2023-03-28 Cheng Jie , Michael C Fu

Monte Carlo estimation in plays a crucial role in stochastic reaction networks. However, reducing the statistical uncertainty of the corresponding estimators requires sampling a large number of trajectories. We propose control variates…

Methodology · Statistics 2021-10-19 Michael Backenköhler , Luca Bortolussi , Verena Wolf

Queuing network control is essential for managing congestion in job-processing systems such as service systems, communication networks, and manufacturing processes. Despite growing interest in applying reinforcement learning (RL)…

Machine Learning · Computer Science 2024-09-06 Ethan Che , Jing Dong , Hongseok Namkoong

We address the problem of estimating steady-state quantities associated to systems of stochastic chemical kinetics. In most cases of interest these systems are analytically intractable, and one has to resort to computational methods to…

Quantitative Methods · Quantitative Biology 2014-01-21 Andreas Milias-Argeitis , John Lygeros , Mustafa Khammash

In network quality of service provisioning, premium services generally require to keep a very small loss probability, which is infeasible to measure directly. The proposed virtual queue scheme estimates the small packet loss probability of…

Networking and Internet Architecture · Computer Science 2010-06-28 Guoqiang Hu , Yuming Jiang , Anne Nevin

In statistics and machine learning, approximation of an intractable integration is often achieved by using the unbiased Monte Carlo estimator, but the variances of the estimation are generally high in many applications. Control variates…

Machine Learning · Statistics 2019-10-16 Ruosi Wan , Mingjun Zhong , Haoyi Xiong , Zhanxing Zhu

Building upon recent developments of force-based estimators with a reduced variance for the computation of densities, radial distribution functions or local transport properties from molecular simulations, we show that the variance can be…

Chemical Physics · Physics 2021-05-18 Samuel W. Coles , Etienne Mangaud , Daan Frenkel , Benjamin Rotenberg

Load balancing algorithms play critical roles in systems where the workload has to be distributed across multiple resources, such as cores in multiprocessor system, computers in distributed computing, and network links. In this paper, we…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-10-20 Shafinaz Islam

Stochastic gradient-based optimisation for discrete latent variable models is challenging due to the high variance of gradients. We introduce a variance reduction technique for score function estimators that makes use of double control…

Machine Learning · Statistics 2022-06-07 Michalis K. Titsias , Jiaxin Shi

The control variates method is a classical variance reduction technique for Monte Carlo estimators that exploits correlated auxiliary variables without introducing bias. In many applications, the quantity of interest can be expressed as a…

Statistics Theory · Mathematics 2025-11-10 Louison Bocquet-Nouaille , Jérôme Morio , Benjamin Bobbia

In this paper we propose and discuss variance reduction techniques for the estimation of quantiles of the output of a complex model with random input parameters. These techniques are based on the use of a reduced model, such as a metamodel…

Methodology · Statistics 2009-01-27 Claire Cannamela , Josselin Garnier , Bertrand Iooss

We exploit the link between the transport equation and derivatives of expectations to construct efficient pathwise gradient estimators for multivariate distributions. We focus on two main threads. First, we use null solutions of the…

Machine Learning · Statistics 2019-03-26 Martin Jankowiak , Theofanis Karaletsos

Driven by applications in telecommunication networks, we explore the simulation task of estimating rare event probabilities for tandem queues in their steady state. Existing literature has recognized that importance sampling methods can be…

Machine Learning · Computer Science 2025-04-22 Ruoning Zhao , Xinyun Chen

Variance reduction is a family of powerful mechanisms for stochastic optimization that appears to be helpful in many machine learning tasks. It is based on estimating the exact gradient with some recursive sequences. Previously, many papers…

Optimization and Control · Mathematics 2025-11-07 Aleksandr Shestakov , Valery Parfenov , Aleksandr Beznosikov

Gradient estimation -- approximating the gradient of an expectation with respect to the parameters of a distribution -- is central to the solution of many machine learning problems. However, when the distribution is discrete, most common…

Machine Learning · Statistics 2024-04-16 Jiaxin Shi , Yuhao Zhou , Jessica Hwang , Michalis K. Titsias , Lester Mackey

Queueing networks are systems of theoretical interest that find widespread use in the performance evaluation of interconnected resources. In comparison to counterpart models in genetics or mathematical biology, the stochastic (jump)…

Methodology · Statistics 2019-06-28 Iker Perez , Giuliano Casale

Variance reduction techniques have been shown by others in the past to be a useful tool to reduce variance in Simulation studies. However, their application and success in the past has been mainly domain specific, with relatively little…

Computational Engineering, Finance, and Science · Computer Science 2013-06-03 Adrian Adewunmi , Uwe Aickelin

Engineering simulators used for steady-state multiphase pipe flows are commonly utilized to predict pressure drop. Such simulators are typically based on either empirical correlations or first-principles mechanistic models. The simulators…

Data Analysis, Statistics and Probability · Physics 2019-06-04 Evgenii Kanin , Andrei Osiptsov , Albert Vainshtein , Evgeny Burnaev

In the presence of multiscale dynamics in a reaction network, direct simulation methods become inefficient as they can only advance the system on the smallest scale. This work presents stochastic averaging techniques to accelerate…

Probability · Mathematics 2016-03-23 Araz Hashemi , Marcel Nunez , Petr Plechac , Dionisios G. Vlachos
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