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We study theoretically the phase diagram of compressible active polar gels such as the actin network of eukaryotic cells. Using generalized hydrodynamics equations, we perform a linear stability analysis of the uniform states in the case of…

Soft Condensed Matter · Physics 2009-11-13 R. Voituriez , J. F. Joanny , J. Prost

Growing experimental evidence shows that cell monolayers can induce long-lived perturbations to their environment, akin to footprints, which in turn influence the global dynamics of the system. Inspired by these observations, we propose a…

Soft Condensed Matter · Physics 2024-09-10 Samuel Bell , Joseph Ackermann , Ananyo Maitra , Raphael Voituriez

Effect of molecular crowding and confinement experienced by protein in the cell during unfolding has been studied by modeling a linear polymer chain on a percolation cluster. It is known that internal structure of the cell changes in time,…

Soft Condensed Matter · Physics 2015-05-14 Amit Raj Singh , Debaprasad Giri , Sanjay Kumar

While the existence of polar ordered states in active systems is well established, the dynamics of the self-assembly processes are still elusive. We study a lattice gas model of self-propelled elongated particles interacting through…

Soft Condensed Matter · Physics 2013-02-11 Christoph. A. Weber , Volker Schaller , Andreas R. Bausch , Erwin Frey

Based on experimental observations it is known that various biological cells exhibit a persistent random walk during migration on flat substrates. The persistent random walk is characterized by `stop-and-go' movements : unidirectional…

Subcellular Processes · Quantitative Biology 2009-11-11 B. Nandy , A. Baumgaertner

Active matter systems encompass both natural and artificially created systems consisting of numerous active particles. These particles actively consume energy to propel themselves or exert mechanical forces, leading to intricate behaviors…

Statistical Mechanics · Physics 2026-05-12 Mintu Karmakar

Eukaryotic cell motility involves a complex network of interactions between biochemical components and mechanical processes. The cell employs this network to polarize and induce shape changes that give rise to membrane protrusions and…

Cell Behavior · Quantitative Biology 2022-01-03 E. Moreno , S. Flemming , F. Font , M. Holschneider , C. Beta , S. Alonso

We characterize cell motion in experiments and show that the transition to collective motion in colonies of gliding bacterial cells confined to a monolayer appears through the organization of cells into larger moving clusters. Collective…

We develop a general theory for active viscoelastic materials made of polar filaments. This theory is motivated by the dynamics of the cytoskeleton. The continuous consumption of a fuel generates a non equilibrium state characterized by the…

Biological Physics · Physics 2009-11-10 Karsten Kruse , Jean-Francois Joanny , Frank Julicher , Jacques Prost , Ken Sekimoto

Cells in tissues can organize into a broad spectrum of structures according to their function. Drastic changes of organization, such as epithelial-mesenchymal transitions or the formation of spheroidal aggregates, are often associated…

Biological Physics · Physics 2016-12-22 Bart Smeets , Ricard Alert , Jiri Pesek , Ignacio Pagonabarraga , Herman Ramon , Romaric Vincent

Living materials such as biological tissues or bacterial colonies are collections of heterogeneous entities of different sizes, capable of autonomous motion, and often capable of cooperating. Such a degree of complexity brings to collective…

Soft Condensed Matter · Physics 2024-01-24 Matteo Paoluzzi , Demian Levis , Ignacio Pagonabarraga

We study the spontaneous motion, binary collisions, and collective dynamics of "polar disks", i.e. purpose-built particles which, when vibrated between two horizontal plates, move coherently along a direction strongly correlated to their…

Soft Condensed Matter · Physics 2016-01-19 Julien Deseigne , Sébastien Léonard , Olivier Dauchot , Hugues Chaté

In this study, we investigate the phenomenon of collective motion in binary mixtures of self-propelled particles. We consider two particle species, each of which consisting of pointlike objects that propel with a velocity of constant…

Soft Condensed Matter · Physics 2013-11-20 Andreas M. Menzel

The dynamics of dry active matter have implications for a diverse collection of biological phenomena spanning a range of length and time scales, such as animal flocking, cell tissue dynamics, and swarming of inserts and bacteria. Uniting…

Soft Condensed Matter · Physics 2021-01-07 David Nesbitt , Gunnar Pruessner , Chiu Fan Lee

We study the emerging collective states in a simple mechanical model of a dense group of self-propelled polar disks with off-centered rotation, confined within a circular arena. Each disk presents self-alignment towards the sum of contact…

Soft Condensed Matter · Physics 2026-04-15 Weizhen Tang , Yating Zheng , Amir Shee , Guozheng Lin , Zhangang Han , Pawel Romanczuk , Cristián Huepe

We present a continuum level analytical model of a droplet of active contractile fluid consisting of filaments and motors. We calculate the steady state flows that result from a splayed polarisation of the filaments. We account for the…

Cell Behavior · Quantitative Biology 2014-02-20 Carl A. Whitfield , Davide Marenduzzo , Raphaël Voituriez , Rhoda J. Hawkins

Experiments have found that diffusion in metabolically active cells is much faster than in dormant cells, especially for large particles. However, the mechanism of this size-dependent diffusion enhancement in living cells is still unclear.…

Biological Physics · Physics 2023-04-04 Lingyu Meng , Yiteng Jin , Yichao Guan , Jiayi Xu , Jie Lin

Contact inhibition limits migration and proliferation of cells in cell colonies. We consider a multiphase field model to investigate the growth dynamics of a cell colony, composed of proliferating cells. The model takes into account the…

Soft Condensed Matter · Physics 2022-03-14 Harish P. Jain , Dennis Wenzel , Axel Voigt

Proliferation and motility are ubiquitous drivers of activity in biological systems. Here, we study a dense binary mixture of motile and proliferating particles with exclusively repulsive interactions, where homeostasis in the proliferating…

Soft Condensed Matter · Physics 2025-06-11 Lukas Hupe , Joanna M. Materska , David Zwicker , Ramin Golestanian , Bartlomiej Waclaw , Philip Bittihn

The complex interactions underlying collective motion in biological systems give rise to emergent behaviours such as flocking, sorting, and cooperative transport. These dynamics often involve species with different motilities coordinating…

Soft Condensed Matter · Physics 2025-06-19 Laura Alvarez , Elena Sesé-Sansa , Demian Levis , Ignacio Pagonabarraga , Lucio Isa