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Public health officials dealing with pandemics like COVID-19 have to evaluate and prepare response plans. This planning phase requires not only looking into the spatiotemporal dynamics and impact of the pandemic using simulation models, but…

Human-Computer Interaction · Computer Science 2020-10-23 Shehzad Afzal , Sohaib Ghani , Hank C. Jenkins-Smith , David S. Ebert , Markus Hadwiger , Ibrahim Hoteit

The use of tiered warnings and multicategorical forecasts are ubiquitous in meteorological operations. Here, a flexible family of scoring functions is presented for evaluating the performance of ordered multicategorical forecasts. Each…

Applications · Statistics 2022-05-02 Robert Taggart , Nicholas Loveday , Deryn Griffiths

Motivated by the questions of risk assessment in climatology (temperature change in North America) and medicine (impact of statin usage and COVID-19 on hospitalized patients), we address the problem of estimating the set in the domain of a…

Methodology · Statistics 2025-04-29 Junting Ren , Fabian J. E. Telschow , Armin Schwartzman

COVID-19 has resulted in a public health global crisis. The pandemic control necessitates epidemic models that capture the trends and impacts on infectious individuals. Many exciting models can implement this but they lack practical…

Computers and Society · Computer Science 2021-04-13 Ou Deng , Kiichi Tago , Qun Jin

The COVID-19 pandemic has posed a heavy burden to the healthcare system worldwide and caused huge social disruption and economic loss. Many deep learning models have been proposed to conduct clinical predictive tasks such as mortality…

Machine Learning · Computer Science 2024-01-24 Junyi Gao , Yinghao Zhu , Wenqing Wang , Yasha Wang , Wen Tang , Ewen M. Harrison , Liantao Ma

Multivariate count time series models are an important tool for the analysis and prediction of infectious disease spread. We consider the endemic-epidemic framework, an autoregressive model class for infectious disease surveillance counts,…

Applications · Statistics 2020-03-16 Johannes Bracher , Leonhard Held

Estimating the true mortality burden of COVID-19 for every country in the world is a difficult, but crucial, public health endeavor. Attributing deaths, direct or indirect, to COVID-19 is problematic. A more attainable target is the "excess…

The Covid-19 pandemic has made clear the need to improve modern multivariate time-series forecasting models. Current state of the art predictions of future daily deaths and, especially, hospital resource usage have confidence intervals that…

Populations and Evolution · Quantitative Biology 2020-06-25 Richard Bao , August Chen , Jethin Gowda , Shiva Mudide

A rich set of frequentist model averaging methods has been developed, but their applications have largely been limited to point prediction, as measuring prediction uncertainty in general settings remains an open problem. In this paper we…

Econometrics · Economics 2025-10-21 Zhongjun Qu , Wendun Wang , Xiaomeng Zhang

The COVID-19 pandemic has strained global public health, necessitating accurate diagnosis and intervention to control disease spread and reduce mortality rates. This paper introduces an interpretable deep survival prediction model designed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Zhusi Zhong , Jie Li , Zhuoqi Ma , Scott Collins , Harrison Bai , Paul Zhang , Terrance Healey , Xinbo Gao , Michael K. Atalay , Zhicheng Jiao

LLM-as-a-judge has become a promising paradigm for using large language models (LLMs) to evaluate natural language generation (NLG), but the uncertainty of its evaluation remains underexplored. This lack of reliability may limit its…

Computation and Language · Computer Science 2025-09-24 Huanxin Sheng , Xinyi Liu , Hangfeng He , Jieyu Zhao , Jian Kang

Causal mediation analysis has become an important and increasingly used framework for evaluating candidate immune response biomarkers in vaccine research. A controlled effects approach has been proposed to estimate controlled risk curves…

Methodology · Statistics 2026-04-09 Qijia He , Bo Zhang

Over the last few decades, various methods have been proposed for estimating prediction intervals in regression settings, including Bayesian methods, ensemble methods, direct interval estimation methods and conformal prediction methods. An…

Machine Learning · Statistics 2024-04-02 Nicolas Dewolf , Bernard De Baets , Willem Waegeman

Time-to-event endpoints are central to evaluate treatment efficacy across many disease areas. Many trial protocols include interim analyses within group-sequential designs that control type I error via spending functions or boundary…

Methodology · Statistics 2026-01-19 Edoardo Ratti , Federico L. Perlino , Stefania Galimberti , Maria G. Valsecchi

We analyze the methodological approach and validity of interpretation of using national-level time-series regression analyses relating epidemic outcomes to policies that estimate many models involving permutations of analytic choices (i.e.,…

Other Quantitative Biology · Quantitative Biology 2024-09-12 Jeremy D. Goldhaber-Fiebert

Conformal prediction, and split conformal prediction as a specific implementation, offer a distribution-free approach to estimating prediction intervals with statistical guarantees. Recent work has shown that split conformal prediction can…

Machine Learning · Statistics 2024-05-01 Nicolas Dewolf , Bernard De Baets , Willem Waegeman

Forecasting infectious disease outbreaks is hard. Forecasting emerging infectious diseases with limited historical data is even harder. In this paper, we investigate ways to improve emerging infectious disease forecasting under operational…

We consider the problem of short- and medium-term electricity load forecasting by using past loads and daily weather forecast information. Conventionally, many researchers have directly applied regression analysis. However, interpreting the…

Methodology · Statistics 2020-07-03 Kei Hirose

As COVID-19 is rapidly spreading across the globe, short-term modeling forecasts provide time-critical information for decisions on containment and mitigation strategies. A main challenge for short-term forecasts is the assessment of key…

Populations and Evolution · Quantitative Biology 2022-11-17 Jonas Dehning , Johannes Zierenberg , F. Paul Spitzner , Michael Wibral , Joao Pinheiro Neto , Michael Wilczek , Viola Priesemann

The fixed-event forecasting setup is common in economic policy. It involves a sequence of forecasts of the same (`fixed') predictand, so that the difficulty of the forecasting problem decreases over time. Fixed-event point forecasts are…

Econometrics · Economics 2024-03-21 Fabian Krüger , Hendrik Plett