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This work presents a single-step deep-learning framework for longitudinal image analysis, coined Segis-Net. To optimally exploit information available in longitudinal data, this method concurrently learns a multi-class segmentation and…

Computer Vision and Pattern Recognition · Computer Science 2021-04-26 Bo Li , Wiro J. Niessen , Stefan Klein , Marius de Groot , M. Arfan Ikram , Meike W. Vernooij , Esther E. Bron

Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Xi Zhu , Wei Zhang , Yijie Li , Lauren J. O'Donnell , Fan Zhang

Diffusion MRI (dMRI) tractography enables in vivo mapping of brain structural connections, but traditional connectome generation is time-consuming and requires gray matter parcellation, posing challenges for large-scale studies. We…

Image and Video Processing · Electrical Eng. & Systems 2025-06-12 Marcus J. Vroemen , Yuqian Chen , Yui Lo , Tengfei Xue , Weidong Cai , Fan Zhang , Josien P. W. Pluim , Lauren J. O'Donnell

Experts use retinal images and vessel trees to detect and diagnose various eye, blood circulation, and brain-related diseases. However, manual segmentation of retinal images is a time-consuming process that requires high expertise and is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Alnur Alimanov , Md Baharul Islam

Accurate detection and segmentation of brain tumors in magnetic resonance imaging (MRI) are critical for effective diagnosis and treatment planning. Despite advances in convolutional neural networks (CNNs) such as U-Net, existing models…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Sashank Makanaboyina

While the major white matter tracts are of great interest to numerous studies in neuroscience and medicine, their manual dissection in larger cohorts from diffusion MRI tractograms is time-consuming, requires expert knowledge and is hard to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-26 Jakob Wasserthal , Peter Neher , Dusan Hirjak , Klaus H. Maier-Hein

Automatic pancreas segmentation in radiology images, eg., computed tomography (CT) and magnetic resonance imaging (MRI), is frequently required by computer-aided screening, diagnosis, and quantitative assessment. Yet pancreas is a…

Computer Vision and Pattern Recognition · Computer Science 2018-04-02 Jinzheng Cai , Le Lu , Fuyong Xing , Lin Yang

Accurate segmentation of punctate white matter lesion (PWML) in infantile brains by an automatic algorithm can reduce the potential risk of postnatal development. How to segment PWML effectively has become one of the active topics in…

Image and Video Processing · Electrical Eng. & Systems 2019-07-02 Yalong Liu , Jie Li , Ying Wang , Miaomiao Wang , Xianjun Li , Zhicheng Jiao , Jian Yang , Xingbo Gao

Purpose Automated segmentation of anatomical structures in medical image analysis is a prerequisite for autonomous diagnosis as well as various computer and robot aided interventions. Recent methods based on deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 Max-Heinrich Laves , Jens Bicker , Lüder A. Kahrs , Tobias Ortmaier

In this paper we describe and validate a longitudinal method for whole-brain segmentation of longitudinal MRI scans. It builds upon an existing whole-brain segmentation method that can handle multi-contrast data and robustly analyze images…

Computer Vision and Pattern Recognition · Computer Science 2023-02-13 Stefano Cerri , Douglas N. Greve , Andrew Hoopes , Henrik Lundell , Hartwig R. Siebner , Mark Mühlau , Koen Van Leemput

The state-of-the-art method for automatically segmenting white matter bundles in diffusion-weighted MRI is tractography in conjunction with streamline cluster selection. This process involves long chains of processing steps which are not…

Computer Vision and Pattern Recognition · Computer Science 2017-03-08 Jakob Wasserthal , Peter F. Neher , Fabian Isensee , Klaus H. Maier-Hein

Background: Alzheimers disease is a progressive neurodegenerative disorder and the main cause of dementia in aging. Hippocampus is prone to changes in the early stages of Alzheimers disease. Detection and observation of the hippocampus…

Image and Video Processing · Electrical Eng. & Systems 2021-06-17 Hossein Yousefi-Banaem , Saber Malekzadeh

Tractography is the process of inferring the trajectories of white-matter pathways in the brain from diffusion magnetic resonance imaging (dMRI). Local tractography methods, which construct streamlines by following local fiber orientation…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Alec Sargood , Lemuel Puglisi , Elinor Thompson , Mirco Musolesi , Daniel C. Alexander

Gray matter (GM) tissue changes have been associated with a wide range of neurological disorders and was also recently found relevant as a biomarker for disability in amyotrophic lateral sclerosis. The ability to automatically segment the…

Computer Vision and Pattern Recognition · Computer Science 2018-06-22 Christian S. Perone , Evan Calabrese , Julien Cohen-Adad

Background: The hippocampus plays a crucial role in memory and cognition. Because of the associated toxicity from whole brain radiotherapy, more advanced treatment planning techniques prioritize hippocampal avoidance, which depends on an…

Medical Physics · Physics 2023-06-16 Yang Lei , Yifu Ding , Richard L. J. Qiu , Tonghe Wang , Justin Roper , Yabo Fu , Hui-Kuo Shu , Hui Mao , Xiaofeng Yang

Neuroimaging to neuropathology correlation (NTNC) promises to enable the transfer of microscopic signatures of pathology to in vivo imaging with MRI, ultimately enhancing clinical care. NTNC traditionally requires a volumetric MRI scan,…

Segmentation of image sequences is an important task in medical image analysis, which enables clinicians to assess the anatomy and function of moving organs. However, direct application of a segmentation algorithm to each time frame of a…

Computer Vision and Pattern Recognition · Computer Science 2018-08-02 Wenjia Bai , Hideaki Suzuki , Chen Qin , Giacomo Tarroni , Ozan Oktay , Paul M. Matthews , Daniel Rueckert

We propose a new method, Patch-CNN, for diffusion tensor (DT) estimation from only six-direction diffusion weighted images (DWI). Deep learning-based methods have been recently proposed for dMRI parameter estimation, using either voxel-wise…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Tobias Goodwin-Allcock , Ting Gong , Robert Gray , Parashkev Nachev , Hui Zhang

Quantitative, volumetric analysis of Magnetic Resonance Imaging (MRI) is a fundamental way researchers study the brain in a host of neurological conditions including normal maturation and aging. Despite the availability of open-source brain…

Quantitative Methods · Quantitative Biology 2019-11-15 Aakash Kaku , Chaitra V. Hegde , Jeffrey Huang , Sohae Chung , Xiuyuan Wang , Matthew Young , Alireza Radmanesh , Yvonne W. Lui , Narges Razavian

Fiber tractography is an important tool of computational neuroscience that enables reconstructing the spatial connectivity and organization of white matter of the brain. Fiber tractography takes advantage of diffusion Magnetic Resonance…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 Tomer Weiss , Sanketh Vedula , Ortal Senouf , Oleg Michailovich , AlexBronstein
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