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Deep unsupervised representation learning has recently led to new approaches in the field of Unsupervised Anomaly Detection (UAD) in brain MRI. The main principle behind these works is to learn a model of normal anatomy by learning to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-09 Christoph Baur , Stefan Denner , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Detection of various lesions in brain MRI is clinically critical, but challenging due to the diversity of lesions and variability in imaging conditions. Current unsupervised learning methods detect anomalies mainly through reconstructing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Tao Yang , Xiuying Wang , Hao Liu , Guanzhong Gong , Lian-Ming Wu , Yu-Ping Wang , Lisheng Wang

Reliably modeling normality and differentiating abnormal appearances from normal cases is a very appealing approach for detecting pathologies in medical images. A plethora of such unsupervised anomaly detection approaches has been made in…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

With the development of medical imaging technology, medical images have become an important basis for doctors to diagnose patients. The brain structure in the collected data is complicated, thence, doctors are required to spend plentiful…

Image and Video Processing · Electrical Eng. & Systems 2020-07-10 Nan Wang , Chengwei Chen , Yuan Xie , Lizhuang Ma

Medical imaging data suffers from the limited availability of annotation because annotating 3D medical data is a time-consuming and expensive task. Moreover, even if the annotation is available, supervised learning-based approaches suffer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Abinav Ravi Venkatakrishnan , Seong Tae Kim , Rami Eisawy , Franz Pfister , Nassir Navab

Deep unsupervised anomaly detection in brain magnetic resonance imaging offers a promising route to identify pathological deviations without requiring lesion-specific annotations. Yet, fragmented evaluations, heterogeneous datasets, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Alexander Frotscher , Christian F. Baumgartner , Thomas Wolfers

Detecting brain lesions as abnormalities observed in magnetic resonance imaging (MRI) is essential for diagnosis and treatment. In the search of abnormalities, such as tumors and malformations, radiologists may benefit from computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Hassan Baker , Austin J. Brockmeier

Deep learning techniques have led to state-of-the-art image super resolution with natural images. Normally, pairs of high-resolution and low-resolution images are used to train the deep learning models. These techniques have also been…

Image and Video Processing · Electrical Eng. & Systems 2022-10-14 Yutaro Iwamoto , Kyohei Takeda , Yinhao Li , Akihiko Shiino , Yen-Wei Chen

Unsupervised anomaly detection in brain imaging is challenging. In this paper, we propose self-supervised masked mesh learning for unsupervised anomaly detection on 3D cortical surfaces. Our framework leverages the intrinsic geometry of the…

Image and Video Processing · Electrical Eng. & Systems 2025-04-01 Hao-Chun Yang , Sicheng Dai , Saige Rutherford , Christian Gaser , Andre F Marquand , Christian F Beckmann , Thomas Wolfers

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

Pathological brain appearances may be so heterogeneous as to be intelligible only as anomalies, defined by their deviation from normality rather than any specific pathological characteristic. Amongst the hardest tasks in medical imaging,…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Walter Hugo Lopez Pinaya , Petru-Daniel Tudosiu , Robert Gray , Geraint Rees , Parashkev Nachev , Sebastien Ourselin , M. Jorge Cardoso

Automated surface inspection is an important task in many manufacturing industries and often requires machine learning driven solutions. Supervised approaches, however, can be challenging, since it is often difficult to obtain large amounts…

Computer Vision and Pattern Recognition · Computer Science 2018-11-19 Matthias Haselmann , Dieter P. Gruber , Paul Tabatabai

Deep neural networks have been extensively studied for undersampled MRI reconstruction. While achieving state-of-the-art performance, they are trained and deployed specifically for one anatomy with limited generalization ability to another…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Xinwen Liu , Jing Wang , Feng Liu , S. Kevin Zhou

Medical segmentation is performed to determine the bounds of regions of interest (ROI) prior to surgery. By allowing the study of growth, structure, and behaviour of the ROI in the planning phase, critical information can be obtained,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 Bao Nguyen , Adam Feldman , Sarath Bethapudi , Andrew Jennings , Chris G. Willcocks

Anomaly detection in medical imaging is to distinguish the relevant biomarkers of diseases from those of normal tissues. Deep supervised learning methods have shown potentials in various detection tasks, but its performances would be…

Image and Video Processing · Electrical Eng. & Systems 2021-12-01 Byungjai Kim , Kinam Kwon , Changheun Oh , Hyunwook Park

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

Local discriminative representation is needed in many medical image analysis tasks such as identifying sub-types of lesion or segmenting detailed components of anatomical structures. However, the commonly applied supervised representation…

Computer Vision and Pattern Recognition · Computer Science 2021-03-25 Huai Chen , Jieyu Li , Renzhen Wang , Yijie Huang , Fanrui Meng , Deyu Meng , Qing Peng , Lisheng Wang

Machine Learning (ML) is increasingly being used for computer aided diagnosis of brain related disorders based on structural magnetic resonance imaging (MRI) data. Most of such work employs biologically and medically meaningful hand-crafted…

Machine Learning · Computer Science 2018-05-04 Ayush Jaiswal , Dong Guo , Cauligi S. Raghavendra , Paul Thompson

Unsupervised lesion detection is a challenging problem that requires accurately estimating normative distributions of healthy anatomy and detecting lesions as outliers without training examples. Recently, this problem has received increased…

Image and Video Processing · Electrical Eng. & Systems 2020-05-04 Xiaoran Chen , Suhang You , Kerem Can Tezcan , Ender Konukoglu

Current unsupervised anomaly localization approaches rely on generative models to learn the distribution of normal images, which is later used to identify potential anomalous regions derived from errors on the reconstructed images. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Julio Silva-Rodríguez , Valery Naranjo , Jose Dolz
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